scholarly journals Modelling of stent expansion dynamics and resultant arterial wall and lesion stresses in a stenosed artery

2012 ◽  
Author(s):  
M. R. Hyre ◽  
S. A. Chae ◽  
R. M. Pulliam
Author(s):  
Alireza Karimi ◽  
Reza Razaghi ◽  
Ahmad Shojaei ◽  
Mahdi Navidbakhsh

AbstractThe stresses induced within plaque tissues and arterial layers during stent expansion inside an atherosclerotic artery can be exceeded from the yield stresses of those tissues and, consequently, lead to plaque or arterial wall rupture. The distribution and magnitude of the stresses in the plaque-artery-stent structure might be distinctly different for different plaque types. In this study, the mechanical properties of six healthy and atherosclerotic human coronary arteries were determined for application in plaque and arterial vulnerability assessment. A nonlinear finite element simulation based on an Ogden material model was established to investigate the effect of plaque types on the stresses induced in the arterial wall during implantation of a balloon expandable coronary stent. The atherosclerotic artery was assumed to consist of a plaque and normal arterial tissues on its outer side. The results indicated a significant influence of plaque types on the maximum stresses induced within the plaque wall and arterial wall during stenting but not when computing maximum stress on the stent. The stress on the stiffest calcified plaque wall was 3.161 MPa, whereas cellular and hypocellular plaques showed relatively less stress on their wall. The highest von Mises stresses within the arterial wall were observed on the hypocellular plaque, whereas the lowest stresses were seen to be located in the calcified and cellular plaques. Although the computed stresses on the arterial wall for the calcified and cellular plaques were not high enough to invoke a rupture, the stress on the hypocellular plaque was relatively higher than that of the strength of the arterial wall. These findings may have implications not only for understanding the stresses induced in plaque and the arterial wall, but also for developing surgeries such as balloon-angioplasty and stenting.


Author(s):  
Sapna Ratan Shah ◽  
Pushkar Kumar

The spread of numerous deadly diseases such as Thrombosis, Diabetes, Atherosclerosis and other cardiac diseases, carry on to be major root of demise and growing public curiosity about the prevention and treatment of such fatal disorders. Body acceleration has very important role on the flow through stenosed artery. In this research work a problem for irregular development in the inner wall of the artery is known atherosclerosis that settled as a result of buildup due to cholesterol on the arterial wall has been discussed. In this work the effects of body acceleration, slip velocity in presence of catheter on the wall shear, velocity profile and flow rate reveal the graphical finding for pulsatile blood flow in narrow blood vessels. Here it is shown that flow rate, velocity and shear stress escalate as body acceleration increases.


Author(s):  
Javier Escuer ◽  
Martina Cebollero ◽  
Estefanía Peña ◽  
Sean McGinty ◽  
Miguel A. Martínez

2016 ◽  
Vol 723 ◽  
pp. 311-315
Author(s):  
Xiang Shen ◽  
Zhong Min Xie ◽  
Yong Quan Deng ◽  
Song Ji

The implantation of an intravascular stent has become a common and widely used minimally invasive treatment for coronary heart disease. But in-stent restenosis (ISR) after stent implantation, especially in tapered vessels, limits the clinical success of stents. In this study, the finite element method (FEM) has been carried out to study the effects of vessel wall thickness on 316L stainless steel stent deployment in tapered arteries. The influence of arterial wall thickness was demonstrated by combination of varied wall thickness and constant wall thickness case. Results indicated that compared to a vessel model with varied thickness from proximal end to distal end, a vessel model with constant thickness had higher vessel wall stress induced by stent expansion. Thus the injury level of vessel wall during stent expansion was overestimated. Numerical simulation results from this study are beneficial to construct a reasonable and accurate expansion model of stent in tapered vessels. The FEM can quantify mechanical properties of stents in tapered vessels, and can compare different modeling strategies for vessel wall thickness, and assist designers to develop new stents especially for tapered vessels.


2006 ◽  
Vol 5 (1) ◽  
pp. 11-12
Author(s):  
Z KOBALAVA ◽  
V MOISEEV ◽  
Y KOTOVSKAYA ◽  
G KIYAKBAEV ◽  
E OZOVA

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