scholarly journals Identification of the dynamic component of the finger arterial pressure-volume relationship

Author(s):  
J. Talts ◽  
R. Raamat ◽  
K. Jagomägi
2008 ◽  
Vol 108 (1) ◽  
pp. 87-93 ◽  
Author(s):  
Colin Forbes Royse ◽  
David F. L. Liew ◽  
Christine E. Wright ◽  
Alistair G. Royse ◽  
James A. Angus

Background Propofol, sevoflurane, and desflurane may cause hemodynamic compromise during anesthesia and critical care management. The aim of the study was to compare these anesthetics during increased dose and recovery to maintenance level. Methods Anesthetized, open-chest New Zealand White rabbits were used to acquire dose-response curves with sevoflurane, desflurane, and propofol, followed by reduction to baseline infusion. Simultaneous high-fidelity left ventricular pressure and volume data were acquired during caval occlusion with a dual-field conductance catheter inserted via an apical stab. The preload recruitable stroke work and the end-diastolic pressure-volume relationship were used as the primary measures of contractility and diastolic function. Results The time-matched controls were stable over time. Propofol and desflurane but not sevoflurane caused dose-dependent reductions in myocardial contractility, although sevoflurane reduced contractility more at 1 minimal alveolar concentration. All anesthetics reduced mean arterial pressure, and significant recovery occurred for sevoflurane and desflurane but not for propofol. The end-diastolic pressure-volume relationship was increased by sevoflurane. Ejection fraction decreased with sevoflurane only. All anesthetics caused dose-dependent vasodilation, with recovery for desflurane and sevoflurane but not propofol. Heart rate was decreased with propofol without significant recovery. Propofol plasma concentrations remained elevated after dose return to baseline infusion rate, suggestive of distribution compartment saturation. Conclusion All three anesthetics caused dose-dependent decreases in cardiovascular function. Recovery of cardiovascular function occurred rapidly with sevoflurane and desflurane, but persistent depression of contractility, vasodilation, mean arterial pressure, and heart rate occurred with propofol during a 30-min recovery period.


1986 ◽  
Vol 18 ◽  
pp. 20-20 ◽  
Author(s):  
A CROTTOGINI ◽  
J BARRA ◽  
M RODRIGUEZCHATRUC ◽  
R ARMENTANO ◽  
E CABRERA ◽  
...  

1958 ◽  
Vol 4 (6) ◽  
pp. 600-606 ◽  
Author(s):  
G. Power ◽  
P. Smith

A set of two-dimensional subsonic flows past certain cylinders is obtained using hodograph methods, in which the true pressure-volume relationship is replaced by various straight-line approximations. It is found that the approximation obtained by a least-squares method possibly gives best results. Comparison is made with values obtained by using the von Kármán-Tsien approximation and also with results obtained by the variational approach of Lush & Cherry (1956).


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