scholarly journals Congenital Protein C Deficiency Combined with a Congenital Abnormal Plasminogen with Deep Venous Thrombosis

1991 ◽  
Vol 2 (2) ◽  
pp. 169-175
Author(s):  
Junki TAKAMATSU ◽  
Kazuo KAGAMI ◽  
Tsunehisa SAKURAI
Keyword(s):  
Venous Thrombosis ◽  
Deep Venous Thrombosis ◽  
Protein C ◽  
Protein C Deficiency ◽  
Abnormal Plasminogen ◽  
Congenital Protein C Deficiency

The Frequency of Type I Heterozygous Protein S and Protein C Deficiency in 141 Unrelated Young Patients with Venous Thrombosis

1988 ◽  
Vol 59 (01) ◽  
pp. 018-022 ◽  
Author(s):  
C L Gladson ◽  
I Scharrer ◽  
V Hach ◽  
K H Beck ◽  
J H Griffin
Keyword(s):  
Venous Thrombosis ◽  
Protein C ◽  
Antithrombin Iii ◽  
Young Patients ◽  
Protein S ◽  
Type I ◽  
Protein S Deficiency ◽  
Protein C Deficiency ◽  
Low Protein ◽  
S Deficiency

SummaryThe frequency of heterozygous protein C and protein S deficiency, detected by measuring total plasma antigen, in a group (n = 141) of young unrelated patients (<45 years old) with venous thrombotic disease was studied and compared to that of antithrombin III, fibrinogen, and plasminogen deficiencies. Among 91 patients not receiving oral anticoagulants, six had low protein S antigen levels and one had a low protein C antigen level. Among 50 patients receiving oral anticoagulant therapy, abnormally low ratios of protein S or C to other vitamin K-dependent factors were presented by one patient for protein S and five for protein C. Thus, heterozygous Type I protein S deficiency appeared in seven of 141 patients (5%) and heterozygous Type I protein C deficiency in six of 141 patients (4%). Eleven of thirteen deficient patients had recurrent venous thrombosis. In this group of 141 patients, 1% had an identifiable fibrinogen abnormality, 2% a plasminogen abnormality, and 3% an antithrombin III deficiency. Thus, among the known plasma protein deficiencies associated with venous thrombosis, protein S and protein C. deficiencies (9%) emerge as the leading identifiable associated abnormalities.

Concurrent Factor V Leiden and Protein C Deficiency Presenting as Mesenteric Venous Thrombosis

2016 ◽  
Vol 82 (4) ◽  
pp. 96-98 ◽  
Author(s):  
Lev N. Korovin ◽  
Mustafa Raoof ◽  
John B. Kettelle ◽  
James H. McClenathan ◽  
Jitesh A. Patel
Keyword(s):  
Venous Thrombosis ◽  
Protein C ◽  
Factor V Leiden ◽  
Factor V ◽  
Mesenteric Venous Thrombosis ◽  
Protein C Deficiency

scholarly journals Unusual venous thrombosis associated with protein C deficiency

1988 ◽  
Vol 7 (3) ◽  
pp. 443-445 ◽  
Author(s):  
Myron E. Schwartz ◽  
Elizabeth B. Harrington ◽  
Jacob H. Rand
Keyword(s):  
Venous Thrombosis ◽  
Protein C ◽  
Protein C Deficiency
Sign in / Sign up

Export Citation Format

Share Document