scholarly journals A Novel Single Nucleotide Polymorphism of the Interleukin-8 Promoter: Its Transcriptional Regulation and Analysis of the Mutation in Periodontal Disease in the Japanese Population

2012 ◽  
Vol 21 (4) ◽  
pp. 427-434
Author(s):  
Yasuhiro Imamura ◽  
Yoshihisa Fujigaki ◽  
Kouichi Higaki ◽  
Nobuo Yoshinari ◽  
Pao-Li Wang
Keyword(s):  
Single Nucleotide Polymorphism ◽  
Transcriptional Regulation ◽  
Periodontal Disease ◽  
Japanese Population ◽  
Interleukin 8 ◽  
Nucleotide Polymorphism ◽  
Single Nucleotide

Single-nucleotide Polymorphism in the CD14 Promoter and Periodontal Disease Expression in a Japanese Population

2003 ◽  
Vol 82 (8) ◽  
pp. 612-616 ◽  
Author(s):  
K. Yamazaki ◽  
K. Ueki-Maruyama ◽  
T. Oda ◽  
K. Tabeta ◽  
Y. Shimada ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphism ◽  
Periodontal Disease ◽  
Japanese Population ◽  
Young Patients ◽  
Genotype Distribution ◽  
Nucleotide Polymorphism ◽  
Single Nucleotide ◽  
Control Subjects ◽  
Significant Difference ◽  
And Gender

It has been reported that there is a relationship between a single-nucleotide polymorphism (SNP) in the promoter region of the CD14 gene at position -159 (C→T) and infectious diseases. The aim of the present study was to test the hypthesis that expression of this SNP correlates with periodontal disease in a Japanese population. The CD14 genotype was determined in 163 subjects with periodontitis and in 104 age- and gender-matched control subjects without periodontitis. The genotype distribution and allele frequency within the periodontitis patients were not significantly different from those of control subjects. There was, however, a significant difference in the genotype distribution between young patients (< 35 yrs) and older patients (≥ 35 yrs). These findings suggest that CD14 -159C/T polymorphism is not related to the development of periodontitis in a Japanese population, but that, within the periodontitis subjects, expression of the SNP may be related to early disease activity.

scholarly journals A Putative Association of a Single Nucleotide Polymorphism in GPR126 with Aggressive Periodontitis in a Japanese Population

PLoS ONE ◽  
2016 ◽  
Vol 11 (8) ◽  
pp. e0160765 ◽  
Author(s):  
Jirouta Kitagaki ◽  
Shizuka Miyauchi ◽  
Yoshihiro Asano ◽  
Atsuko Imai ◽  
Shinji Kawai ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphism ◽  
Japanese Population ◽  
Aggressive Periodontitis ◽  
Nucleotide Polymorphism ◽  
Single Nucleotide

A single-nucleotide polymorphism in the human THADA gene is associated with circulating resistin in the general Japanese population

2011 ◽  
Vol 2 (4) ◽  
pp. 190-196 ◽  
Author(s):  
Ryoichi Kawamura ◽  
Yasuharu Tabara ◽  
Hiroshi Onuma ◽  
Ryuichi Kawamoto ◽  
Jun Ohashi ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphism ◽  
Japanese Population ◽  
Nucleotide Polymorphism ◽  
Single Nucleotide ◽  
General Japanese Population

scholarly journals Single-nucleotide Polymorphism (SNP) in β-Defensin 2 in a Japanese Population and an Effect of - 1029 SNP on Promoter Activity

2005 ◽  
Vol 2 (2) ◽  
pp. 80-84 ◽  
Author(s):  
Kaoru Kusano ◽  
Yoshihiro Abiko ◽  
Michiko Nishimura ◽  
Toshiya Arakawa ◽  
Maiko Takeshima ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphism ◽  
Japanese Population ◽  
Promoter Activity ◽  
Nucleotide Polymorphism ◽  
Single Nucleotide
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