scholarly journals Current Status of Double Cancer and Its Countermeasures. Present Status and Management of Multiple Primary Esophageal Cancer Associated with Head and Neck Cancer.

1998 ◽  
Vol 49 (2) ◽  
pp. 151-155 ◽  
Author(s):  
Hiroshi Watanabe
Keyword(s):  
Esophageal Cancer ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Present Status ◽  
Current Status ◽  
Double Cancer ◽  
Multiple Primary

Screening and treatment strategy for double cancer for esophageal cancer surgery patients.

2020 ◽  
Vol 38 (4_suppl) ◽  
pp. 336-336
Author(s):  
Takashi Ogata ◽  
Yota Shimoda ◽  
Kazuki Kano ◽  
Keisuke Koumori ◽  
Hayato Watanabe ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Treatment Strategy ◽  
Cancer Surgery ◽  
Double Cancer ◽  
Esophageal Cancer Surgery ◽  
Double Cancers

336 Background: Esophageal cancer treatment, especially esophagectomy, is highly invasive, so treatment strategies are considered in view of existing double cancers. On the other hand, in Japan, 90% of esophageal cancers are squamous cell carcinoma, and it is known that there are a large proportion of head and neck cancers for double cancers as field cancerization. Methods: The aim of this study is to investigate the types of double cancer, simultaneous/metachronous, and the frequency and treatment policy of head and neck cancer as a particularly high coexistence rate for esophageal cancer surgery patient. The subjects were 304 patients who underwent esophagectomy performed from April 2010 to December 2017. All patients were examined with high-definition endoscopy with NBI by certificated endoscopist at the first visit as a search for simultaneous double cancer from the pharynx to the stomach. And after esophagectomy, endoscopy was also performed to check for metachronous double cancers in the remaining esophagus, gastric tube, and pharynx at least every 2 years. Results: The number of double cancer cases was found in 94 cases (30.9%), and the total number of double cancer cases was 122. Head and neck cancer(33 cases), stomach cancer(16 cases), and colon cancer(12 cases) were observed as the main course of double cancers. In double cancer cases, 47cases(50.0%) were metachronous, 35cases(37.2%) were simultaneous, and 12cases(12.8%) were both synchronous. The most common double cancer was head and neck cancer(33 cases:35.1%), and 23 cases were simultaneous, 10 cases were metachronous. As treatment strategy for head and neck cancer, endoscopic laryngo-pharyngo surgery(ELPS) were 19 cases. 10 cases(52.7%) were synchronous cancers, and 9 cases (47.3%) were metachronous cancers which were detected during follow-up after esophagectomy. Conclusions: Head and neck cancer associated with esophageal cancer surgery is the most common type of double cancer, and 1/3 of ELPS cases have been detected by follow-up endoscopy after esophagectomy, so endoscopic surveillance was also considered important.

Significance of multimodality therapy for esophageal cancer synchronously or metachronously associated with head and neck cancer.

2013 ◽  
Vol 31 (4_suppl) ◽  
pp. 132-132
Author(s):  
Yasue Kimura ◽  
Masaru Morita ◽  
Hiroyuki Kawano ◽  
Hajime Ohtsu ◽  
Koji Ando ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Morbidity Rate ◽  
Control Group ◽  
Double Cancer ◽  
Definitive Chemoradiotherapy ◽  
Subtotal Esophagectomy ◽  
Cancer Group

132 Background: Esophageal cancer is highly aggressive and until recently is associated with a poor prognosis. Another clinical problem of esophageal cancer is the frequent association of head and neck cancer. The therapy for esophageal cancer and head and neck cancer is difficult. Definitive chemoradiotherapy is frequently indicated, while invasive surgical resections have been aggressively performed for patients with esophageal cancer associated with head and neck cancer. Methods: The Japanese 202 patients underwent esophagectomy were divided into two groups according to the association of head and neck cancer. The clinicopathological factors and the method of operations were evaluated and statistically analyzed. Results: The double cancer group included 26 (12.9%) patients that had the cancer of esophagus and the head and neck either synchronously or metachronously, while the control group included 176 (87.1%) patients with esophageal cancer. Seventeen patients were operated synchronously in double cancer group. No statistically significant differences were recognized in other clinical backgrounds such as the gender, location of the tumor, etc. Several types of operations were performed for two groups, such as subtotal esophagectomy, total laryngo-pharyngo-esophagectomy, cervical esophagectomy and laryngo-pharyngectomy and free jejunal transfer.salvage esophagectomy, and two-staged operation after definitive chemoradiotherapy. Salvage esophagectomy was performed in five patients with either remnant or recurrent esophageal cancer after definitive chemoradiotherapy. The mortality as well as morbidity rate of the double cancer group was not significantly different from the control group. Furthermore, patients’ prognosis was similar in the two groups. Conclusions: Esophagectomy can be an effective treatment option by adopting techniques that appropriate for each cases, such as staged operations after definitive chemoradiotherapy, muscular flaps and microvascular anastomosis, even in patients with double cancers of the esophagus and the head and neck cancer.

Multiple Primary Malignancies in Patients with Head and Neck Cancer

2007 ◽  
Vol 58 (2) ◽  
pp. 205-205
Author(s):  
H. Iguchi ◽  
M. Kusuki ◽  
A. Nakamura ◽  
A. Kanazawa ◽  
K. Hachiya ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Multiple Primary Malignancies ◽  
Multiple Primary

Clinical Analysis of Second Primary Esophageal Cancer after Treatment for Head and Neck Cancer

2021 ◽  
Vol 72 (4) ◽  
pp. 196-203
Author(s):  
Kohei Saisho ◽  
Satoru Matono ◽  
Naoki Mori ◽  
Haruhiro Hino ◽  
Masahiro Fujisaki ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Clinical Analysis ◽  
Second Primary

Current Status of Clinical Trials in Head and Neck Cancer 2014

2015 ◽  
Vol 152 (3) ◽  
pp. 410-417 ◽  
Author(s):  
Jeffrey C. Liu ◽  
John A. Ridge ◽  
David M. Brizel ◽  
Brian O’Sullivan ◽  
Ezra W. Cohen ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Current Status
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