scholarly journals Imaging Endolymphatic Hydrops at 3 Tesla Using 3D-FLAIR with Intratympanic Gd-DTPA Administration

2008 ◽  
Vol 7 (2) ◽  
pp. 85-91 ◽  
Author(s):  
Shinji NAGANAWA ◽  
Hiroko SATAKE ◽  
Shingo IWANO ◽  
Hiroshi FUKATSU ◽  
Michihiko SONE ◽  
...  
Keyword(s):  
Endolymphatic Hydrops ◽  
3 Tesla ◽  
3D Flair

Comparison between high-resolution 3D-IR with real reconstruction and 3D-flair sequences in the assessment of endolymphatic hydrops in 3 tesla

2020 ◽  
Vol 140 (11) ◽  
pp. 883-888
Author(s):  
Víctor Manuel Suárez Vega ◽  
Pablo Dominguez ◽  
Fanny Meylin Caballeros Lam ◽  
Jose Ignacio Leal ◽  
Nicolás Perez-Fernandez
Keyword(s):  
High Resolution ◽  
Endolymphatic Hydrops ◽  
3 Tesla ◽  
3D Flair

scholarly journals Audiovestibular Phenotypes and Advanced Magnetic Resonance Imaging Features of Cochlin Gene Mutation Carriers

2019 ◽  
Vol 24 (4) ◽  
pp. 166-173
Author(s):  
Giorgio Conte ◽  
Francesco Lo Russo ◽  
Luca Caschera ◽  
Diego Zanetti ◽  
Pierangela Castorina ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Endolymphatic Hydrops ◽  
Heterozygous Mutation ◽  
Main Role ◽  
Imaging Features ◽  
Resonance Imaging ◽  
Flair Sequence ◽  
Factor C ◽  
3D Flair

Objective: To describe clinical and imaging findings in a group of patients affected by nonsyndromic deafness A9 (DFNA9), using advanced magnetic resonance imaging (MRI) with 3-dimensional (3D) fluid-attenuated inversion recovery (FLAIR) sequence. Method: A retrospective case review was conducted in a tertiary referral center in Italy. Four sequential adult DFNA9-affected patients, who had undergone MRI at our Department between January 2017 and June 2018, were enrolled (male = 2, female = 2; median age: 65.6 years; 8 diseased ears analyzed). Three patients were relatives; the fourth was unrelated. The main outcome measures – age, sex, records of audiological and vestibular testing, genetic assessment, MRI findings – were analyzed. Results: All subjects suffered from bilateral progressive sensorineural hearing loss, more severely at the high frequencies and with a typical clinical pattern of bilateral chronic degenerative cochleovestibular deficit. Aural fullness was reported at the onset of the disease. All patients revealed a pathogenic heterozygous mutation in the Limulus factor C, Coch-5b2 and Lgl1 domain of cochlin. None of the patients showed a significant vestibular and cochlear endolymphatic hydrops at MRI, while high bilateral contrast enhancement on 4-h delayed postcontrast 3D FLAIR sequence was observed in all ears. Conclusions: Increased perilymph enhancement on 4-h delayed postcontrast 3D FLAIR sequence is the common imaging feature of DFNA9 ears, suggesting that blood-labyrinthine barrier breakdown may play the main role in the pathophysiology of this disease. Significant hydrops has been excluded by MRI. This finding might be clinically useful in differentiating DFNA9 disease from other pathologies with similar clinical findings like Ménière’s disease.

scholarly journals Signal Alteration of the Cochlear Perilymph on 3 Different Sequences after Intratympanic Gd-DTPA Administration at 3 Tesla: Comparison of 3D-FLAIR, 3D-T1-weighted Imaging, and 3D-CISS

2010 ◽  
Vol 9 (2) ◽  
pp. 65-71 ◽  
Author(s):  
Masahiro YAMAZAKI ◽  
Shinji NAGANAWA ◽  
Hisashi KAWAI ◽  
Takashi NIHASHI ◽  
Tsutomu NAKASHIMA
Keyword(s):  
3 Tesla ◽  
3D Flair
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