scholarly journals Occult Expression of Non Syndromic Sex Cord Tumor with Annular Tubules in Ovary with Coexistent Cervical Fibroid

2020 ◽  
Vol 06 (1&2) ◽  
pp. 1-4
Author(s):  
Khushboo Dewan ◽  
Keyword(s):  
Granulosa Cell ◽  
Sertoli Cell ◽  
Ovarian Tumor ◽  
Standard Treatment ◽  
Malignant Potential ◽  
Morphological Features ◽  
Rare Occurrence ◽  
Treatment Protocols ◽  
Low Malignant Potential

Sex Cord Tumor with Annular Tubules (SCTAT) is a rare ovarian tumor. It has morphological features intermediate between that of granulosa cell and sertoli cell. It is considered an estrogen and progesterone secreting tumor carrying low malignant potential. Due to its rare occurrence, its clinical recognition is difficult; hence, there are no standard treatment protocols. We present an incidentally detected SCTAT in the ovary coexisting with cervical fibroid.

Operative staging and conservative surgery in the management of low malignant potential ovarian tumors

1992 ◽  
Vol 2 (3) ◽  
pp. 113-118 ◽  
Author(s):  
W. R. Robinson ◽  
J. P. Curtin ◽  
C. P. Morrow
Keyword(s):  
Ovarian Tumor ◽  
Malignant Tumors ◽  
Frozen Section ◽  
Conservative Surgery ◽  
Malignant Potential ◽  
Factors Affecting ◽  
Surgery Patient ◽  
Intraoperative Management ◽  
Low Malignant Potential ◽  
Histopathologic Findings

The medical records of 45- patients with intraoperative diagnosis of borderline or low malignant potential (LMP) ovarian tumor were reviewed to identify factors affecting intraoperative management. The correlation between gross and histologic staging was examined, as was the complication rate following surgery. Patient age and presence of qualifying pathologic terms on frozen section diagnosis were the only important factors relating to performance of surgical procedure. Surgical complications were closely associated with non-conservative surgery. Thirteen of 14 (92.8%) patients with significant complications had a hysterectomy. These 14 patients had staging procedures at essentially the same rate as the entire population. Thirteen of 45 patients (28.8%) thought to have LMP by frozen section had a different diagnosis on permanent review; 5 were benign and 8 were frankly malignant, confirming the limitations of frozen section in the diagnosis of LMP ovarian tumor. Of 40 with LMP or frankly malignant tumors 5(12.5%) were upstaged based on unsuspected histopathologic findings. These results indicate the need for a standard approach to staging in patients who are suspected to have an LMP ovarian tumor and should encourage the performance of conservative surgery when appropriate.

Xp11 translocation renal cell carcinoma with morphological features mimicking multilocular cystic renal neoplasm of low malignant potential: a series of six cases with molecular analysis

2020 ◽  
pp. jclinpath-2020-206681
Author(s):  
Yankun Song ◽  
Xiaoxue Yin ◽  
Qiuyuan Xia ◽  
Linmao Zheng ◽  
Jin Yao ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Gene Fusion ◽  
Malignant Potential ◽  
Morphological Features ◽  
Low Grade ◽  
Renal Neoplasm ◽  
Psammoma Bodies ◽  
Low Malignant Potential

AimsXp11 translocation renal cell carcinoma (RCC) is a distinctive subtype of RCC with TFE3 (Transcription Factor Binding to IGHM Enhancer 3) gene rearrangement. The gross features in most Xp11 translocation RCCs closely resemble clear cell RCCs. In this study, we report six cases of Xp11 translocation RCCs with a unique multicystic architecture, reminiscent of multilocular cystic renal cell neoplasm of low malignant potential (MCRN-LMP).Methods and resultsMicroscopically, the renal mass was well circumscribed with multilocular cystic architecture. The cyst walls and septa were mostly lined by a single layer of cells with clear cytoplasm and low-grade nuclei, reminiscent of MCRN-LMP. Psammoma bodies were detected in four cases. One particular patient was misdiagnosed with benign cysts in local hospitals and led to second operation. Tumour cells were settled according to the track of the first surgical procedure. TFE3 fluorescence in situ hybridization (FISH) assay confirmed the diagnosis of Xp11 translocation RCCs. FISH and RNA sequencing analyses confirmed MED15-TFE3 gene fusion in all six cases. Respective patients were alive, without any recent evidence of disease recurrence and/or metastasis.ConclusionsHere, we introduce a relatively inertia-variant of Xp11 translocation RCC which mimics MCRN-LMP. The distinctive morphological condition is linked to MED15-TFE3 gene fusion. In fact, renal neoplasms with morphological features of MCRN-LMP, especially those containing psammoma bodies, should be routinely evaluated for evidence of TFE3 gene rearrangements.

Impact of staging surgery in the outcomes of patients with early-stage low malignant potential ovarian tumor (LMPOT)

2004 ◽  
Vol 22 (14_suppl) ◽  
pp. 5092-5092
Author(s):  
P. M. Morice ◽  
S. Camatte ◽  
A. Thoury ◽  
D. Atallah ◽  
C. Lhomme ◽  
...  
Keyword(s):  
Ovarian Tumor ◽  
Early Stage ◽  
Malignant Potential ◽  
Low Malignant Potential ◽  
Staging Surgery

Impact of staging surgery in the outcomes of patients with early-stage low malignant potential ovarian tumor (LMPOT)

2004 ◽  
Vol 22 (14_suppl) ◽  
pp. 5092-5092
Author(s):  
P. M. Morice ◽  
S. Camatte ◽  
A. Thoury ◽  
D. Atallah ◽  
C. Lhomme ◽  
...  
Keyword(s):  
Ovarian Tumor ◽  
Early Stage ◽  
Malignant Potential ◽  
Low Malignant Potential ◽  
Staging Surgery

Virilizing Ovarian Tumor of Low Malignant Potential Associated with Antecedent Tamoxifen Use for Breast Cancer

1998 ◽  
Vol 68 (3) ◽  
pp. 293-296 ◽  
Author(s):  
Daniel V. Surbek ◽  
Irene Hoesli ◽  
Joachim Torhorst ◽  
Alfonso C. Almendral ◽  
Athanassios Dellas ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Ovarian Tumor ◽  
Malignant Potential ◽  
Low Malignant Potential
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