A case of Steroid Responsive Encephalopathy associated with Autoimmune Thyroiditis: A Diagnostic Dilemma

Pratap Singh;

doi:10.24321/2349.7181.201704

Cytomorphological features of oncocytic variant of papillary thyroid carcinoma with lymphocytic thyroiditis

Asian Journal of Oncology ◽

10.4103/2454-6798.197377 ◽

2016 ◽

Vol 02 (02) ◽

pp. 085-087 ◽

Cited By ~ 1

Author(s):

Nivedita Patnaik ◽

Preeti Diwaker ◽

Alphy Varughese ◽

Vinod Arora ◽

Bharat Singh

Keyword(s):

Papillary Thyroid Carcinoma ◽

Thyroid Carcinoma ◽

Autoimmune Thyroiditis ◽

Needle Aspiration ◽

Surrounding Tissue ◽

Papillary Thyroid ◽

Diagnostic Dilemma ◽

Lymphocytic Thyroiditis ◽

Wide Range ◽

Oncocytic Variant

AbstractCytological diagnosis of hurthle cell lesions of thyroid is a diagnostic dilemma. Presence of hurthle cells on fine needle aspiration (FNA) leads to a wide range of differential diagnosis including benign and malignant entities. The oncocytic variant of papillary thyroid carcinoma (PTC) is one entity of the vast list of differentials of which very few cases have been reported to date. We report a case of oncocytic variant of PTC in a 28-year-old female diagnosed on cytomorphology. The findings of FNA smears of the first aspirate were not sufficient for a definitive diagnosis. Repeat FNA was done to rule out the possibility of autoimmune thyroiditis/thyroid neoplasm. The repeat FNA smears showed oncocytic cells present in papillary and loosely cohesive clusters. Many of the cells displayed nuclear features of PTC and the case was finally diagnosed as PTC; oncocytic variant. Thyroidectomy specimen revealed PTC; oncocytic variant with lymphocytic thyroiditis in the surrounding tissue. Thus, in cytology practice, concurrent autoimmune thyroiditis may pose a problem in diagnosis of PTC; oncocytic variant.

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Abstract #330 Insulinoma or Prancreatic Adenocarcinoma – A Diagnostic Dilemma?

Endocrine Practice ◽

10.1016/s1530-891x(20)46674-1 ◽

2019 ◽

Vol 25 ◽

pp. 143-144

Author(s):

Muhammad Ansar ◽

Joseph Dillon

Keyword(s):

Diagnostic Dilemma

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VHL: a diagnostic dilemma

Nature India ◽

10.1038/nindia.2009.251 ◽

2009 ◽

Keyword(s):

Diagnostic Dilemma

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The systemic disease: autoimmune thyroiditis – interdisciplinary collaboration: Homeopathy – micro-immunotherapy – orthomolecular therapy

Allgemeine Homöopathische Zeitung ◽

10.1055/s-0037-1601096 ◽

2017 ◽

Vol 262 (02) ◽

pp. 2-76

Author(s):

I Chammah ◽

H Orfanos-Boeckel ◽

G Schlegel

Keyword(s):

Autoimmune Thyroiditis ◽

Interdisciplinary Collaboration ◽

Systemic Disease

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SERUM THYROTROPHIN AND THE RESPONSE TO THYROTROPHIN RELEASING HORMONE IN SYMPTOMLESS AUTOIMMUNE THYROIDITIS AND IN BORDERLINE AND OVERT HYPOTHYROIDISM

Acta Endocrinologica ◽

10.1530/acta.0.0750274 ◽

1974 ◽

Vol 75 (2) ◽

pp. 274-285 ◽

Cited By ~ 42

Author(s):

A. Gordin ◽

P. Saarinen ◽

R. Pelkonen ◽

B.-A. Lamberg

Keyword(s):

Autoimmune Thyroiditis ◽

Elevated Serum ◽

Mean Value ◽

Primary Hypothyroidism ◽

Overt Hypothyroidism ◽

Thyrotrophin Releasing Hormone ◽

Releasing Hormone ◽

The Mean ◽

The Individual ◽

Serum Tsh

ABSTRACT Serum thyrotrophin (TSH) was determined by the double-antibody radioimmunoassay in 58 patients with primary hypothyroidism and was found to be elevated in all but 2 patients, one of whom had overt and one clinically borderline hypothyroidism. Six (29%) out of 21 subjects with symptomless autoimmune thyroiditis (SAT) had an elevated serum TSH level. There was little correlation between the severity of the disease and the serum TSH values in individual cases. However, the mean serum TSH value in overt hypothyroidism (93.4 μU/ml) was significantly higher than the mean value both in clinically borderline hypothyroidism (34.4 μU/ml) and in SAT (8.8 μU/ml). The response to the thyrotrophin-releasing hormone (TRH) was increased in all 39 patients with overt or borderline hypothyroidism and in 9 (43 %) of the 21 subjects with SAT. The individual TRH response in these two groups showed a marked overlap, but the mean response was significantly higher in overt (149.5 μU/ml) or clinically borderline hypothyroidism (99.9 μU/ml) than in SAT (35.3 μU/ml). Thus a normal basal TSH level in connection with a normal response to TRH excludes primary hypothyroidism, but nevertheless not all patients with elevated TSH values or increased responses to TRH are clinically hypothyroid.

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