scholarly journals Unani and Modern Aspect of Psoriasis (Da-us-Sadaf): A Review

2021 ◽  
Vol 10 (01) ◽  
pp. 27-30
Author(s):  
Nabeela Sultan ◽  
Keyword(s):  
Autoimmune Disease ◽  
Social Exclusion ◽  
Skin Condition ◽  
Primary Concern ◽  
Modern Aspect ◽  
Ancient Times ◽  
Chronic Skin

Psoriasis is a red and scaly chronic skin condition of unknown cause. The primary concern to most patients is unsightly appearance. Social exclusion discrimination is psychologically devastating for individuals suffering from psoriasis and their families. It can occur at any age. Psoriasis could be defined as an autoimmune disease. But no autoantigen responsible for this disease has been defined yet. In the Unani system of medicine, psoriasis is described in various headings such as Da-us-Sadaf, Taqashshure Jild, Qooba-e-mutaqashshira, Chambal and Al sadafiya, but there is no description of the word psoriasis and its cause in the Unani system of medicine. But a renowned Unani physician Ibn-e-zuhr use the term Taqasshure Jild, where abnormal humor (sauda-e-ghaleez in skin) is responsible for this disorder. The sauda-e-ghaleez hampers the skin nutrition hence the skin becomes dead and falls out in the form of scale. Unani physicians are successfully treating this ailment since ancient times by adopting different modes of treatment. This paper aims to explore each and every aspect of this disease.

Understanding the Experiences of Anger in the Onset and Progression of Psoriasis: A Qualitative Study Using Social Media (Preprint)

2021 ◽  
Author(s):  
Olivia Hughes ◽  
Rachael Hunter
Keyword(s):  
Social Media ◽  
Qualitative Interviews ◽  
Psychosocial Interventions ◽  
Skin Condition ◽  
Future Research ◽  
Social Media Platforms ◽  
Chronic Skin ◽  
Skin Conditions ◽  
The Impact

BACKGROUND Psoriasis is a chronic inflammatory skin condition, which can be affected by stress. Living with psoriasis can trigger negative emotions, which may influence quality of life. OBJECTIVE This study explored the experiences of people with psoriasis with attention to the potential role of anger in the onset and progression of the chronic skin condition. METHODS Semi-structured qualitative interviews were conducted with twelve participants (n=5 females, n=7 males) recruited online from an advert on a patient charity’s social media platforms. Data were transcribed and analysed using thematic analysis. RESULTS Four key themes were identified: (1) ‘I get really angry with the whole situation:’ anger at the self and others, (2) the impact of anger on psoriasis: angry skin, (3) shared experiences of distress, and (4) moving past anger to affirmation. CONCLUSIONS Findings suggest that anger can have a perceived impact on psoriasis through contributing to sensory symptoms and unhelpful coping cycles and point to a need for enhanced treatment with more psychological support. The findings also highlight the continued stigma which exists for people living with skin conditions and how this may contribute to, and sustain, anger for those individuals. Future research could usefully focus on developing targeted psychosocial interventions to promote healthy emotional coping with psoriasis.

scholarly journals Hidradenitis Suppurativa: “A surgical Update with Review of Literature”

2021 ◽  
pp. 1-4
Author(s):  
UwaisRiaz Ul Hasan ◽  
◽  
Farooq Qureishi ◽  
Khathija Hasan ◽  
Nidal Khraisat ◽  
...  
Keyword(s):  
Social Life ◽  
Hidradenitis Suppurativa ◽  
Skin Condition ◽  
The Body ◽  
Fistula Formation ◽  
Sweat Glands ◽  
Chronic Patients ◽  
Foul Smell ◽  
Chronic Skin ◽  
End Stage

Hidradenitis suppurativa (HS) is a chronic skin disease primarily affecting the sweat glands apocrine zone of the body and what starts initially as an abscess progresses to nodules, sinus tracts, with cicatrisation fistula formation and ulcers. It is common to see all the stages of clinical spectrum viz multiple solitary abscess to nodules with sinus, fistulas with ulceration and cicatrisation in chronic patients. This chronic illness takes a toll on the psyche of these individuals as the need to avoid foul smell and the constant need for dressing dictate their social life. The patients are notoriously know for follow up for years. A low self-esteem and depression are companions of hidradenitis suppurativa (HS) individuals. Early involvement of the surgeon can substantially improve the progress and evolution of this chronic skin condition and could obviate the development of SCC the end stage of all Chronic neglected Hidradenitis suppurativa (HS) cases especially in the hi risk older age group of individuals

Psoriatic arthritis

2013 ◽  
pp. 890-900
Author(s):  
Laura C. Coates ◽  
Philip S. Helliwell
Keyword(s):  
Psoriatic Arthritis ◽  
Skin Condition ◽  
Patient Reported Outcome ◽  
New Drugs ◽  
Screening Tools ◽  
North Americans ◽  
The Metabolic Syndrome ◽  
Patient Reported ◽  
Chronic Skin ◽  
The Impact

Psoriasis is a chronic skin condition affecting about 3% of Europeans and North Americans. About 15% of people afflicted with psoriasis will develop psoriatic arthritis—cutaneous risk factors for this are psoriasis of the nails, scalp, and flexures. Since most cases of arthritis develop in people with psoriasis, new screening tools, both clinical and imaging, are available. Some genetic factors may also explain susceptibility and severity. Historically, five clinical subgroups have been described but these may be simplified to axial and peripheral involvement, the latter dividing into oligo- and polyarticular patterns. The importance of these clinical subdivisions is still under debate and research but it is clear that there is marked heterogeneity in all manifestations of this disease. In recent times the importance of extra-articular features has gained prominence such that the metabolic syndrome and cardiovascular morbidity are now seen as important features of ’psoriatic disease’. The diverse changes seen in bone on imaging reflect both the underlying pathogenic mechanisms and the ways in which the disease progresses. Recent work with animal models and immunohistochemistry has further advanced our understanding of these features. In the biologic era renewed interest in psoriatic arthritis has stimulated research into outcome assessment and permitted clearer understanding of how these new drugs work on the different aspects of the disease. In addition, improved recognition of the impact of the disease on the person has stimulated the development of new patient-reported outcome tools.

Psoriatic arthritis

2013 ◽  
Author(s):  
Laura C. Coates ◽  
Philip S. Helliwell
Keyword(s):  
Psoriatic Arthritis ◽  
Skin Condition ◽  
Patient Reported Outcome ◽  
New Drugs ◽  
Screening Tools ◽  
North Americans ◽  
The Metabolic Syndrome ◽  
Patient Reported ◽  
Chronic Skin ◽  
The Impact

Psoriasis is a chronic skin condition affecting about 3% of Europeans and North Americans. About 15% of people afflicted with psoriasis will develop psoriatic arthritis—cutaneous risk factors for this are psoriasis of the nails, scalp, and flexures. Since most cases of arthritis develop in people with psoriasis, new screening tools, both clinical and imaging, are available. Some genetic factors may also explain susceptibility and severity. Historically, five clinical subgroups have been described but these may be simplified to axial and peripheral involvement, the latter dividing into oligo- and polyarticular patterns. The importance of these clinical subdivisions is still under debate and research but it is clear that there is marked heterogeneity in all manifestations of this disease. In recent times the importance of extra-articular features has gained prominence such that the metabolic syndrome and cardiovascular morbidity are now seen as important features of 'psoriatic disease'. The diverse changes seen in bone on imaging reflect both the underlying pathogenic mechanisms and the ways in which the disease progresses. Recent work with animal models and immunohistochemistry has further advanced our understanding of these features. In the biologic era renewed interest in psoriatic arthritis has stimulated research into outcome assessment and permitted clearer understanding of how these new drugs work on the different aspects of the disease. In addition, improved recognition of the impact of the disease on the person has stimulated the development of new patient-reported outcome tools.

scholarly journals Ameliorating Effect of Oral Guggulsterone Administration in Imiquimod-Induced Psoriasis in Mice

2018 ◽  
pp. 15-23
Author(s):  
Raghad A. Khaleel ◽  
Munaf H. Zalzala
Keyword(s):  
Inflammatory Cells ◽  
Skin Inflammation ◽  
Severity Index ◽  
Skin Condition ◽  
Keratinocyte Differentiation ◽  
Vehicle Suspension ◽  
Control Group ◽  
Response Modifier ◽  
Chronic Skin ◽  
Immune Response Modifier

Psoriasis is a common chronic skin condition characterized by infiltration of inflammatory cells into the epidermis and altered keratinocyte differentiation. In this work, psoriasis was induced by an imiquimod 5% cream, an immune response modifier that can induce psoriasis-like skin inflammation when applied topically in mice. Guggulsterone prepared as a suspension and has been orally given to mice before imiquimod application. The results of the current study showed that guggulsterone suspension can significantly reduce psoriasis area and severity index in (guggul suspension+imiquimod group as compared with both control group and (vehicle suspension+imiquimod ) group.  

scholarly journals Hidradenitis Suppurativa: “A surgical Update with Review of Literature”

2021 ◽  
pp. 1-4
Author(s):  
UwaisRiaz UlHasan ◽  
◽  
Moath AbdulAziz AlMasoud ◽  
Noura Al Dossary ◽  
◽  
...  
Keyword(s):  
Social Life ◽  
Hidradenitis Suppurativa ◽  
Skin Condition ◽  
The Body ◽  
Fistula Formation ◽  
Sweat Glands ◽  
Chronic Patients ◽  
Foul Smell ◽  
Chronic Skin ◽  
End Stage

Hidradenitis suppurativa (HS) is a chronic skin disease primarily affecting the sweat glands apocrine zone of the body and what starts initially as an abscess progresses to nodules, sinus tracts, with cicatrisation fistula formation and ulcers. It is common to see all the stages of clinical spectrum viz multiple solitary abscess to nodules with sinus, fistulas with ulceration and cicatrisation in chronic patients. This chronic illness takes a toll on the psyche of these individuals as the need to avoid foul smell and the constant need for dressing dictate their social life. The patients are notoriously know for follow up for years. A low self-esteem and depression are companions of hidradenitis suppurativa (HS) individuals. Early involvement of the surgeon can substantially improve the progress and evolution of this chronic skin condition and could obviate the development of SCC the end stage of all Chronic neglected Hidradenitis suppurativa (HS) cases especially in the hi risk older age group of individuals

Beliefs Perceptions and Knowledge among Alopecia Areata patients: A Cross-Sectional Study in the University of Lahore

2021 ◽  
Vol 15 (9) ◽  
pp. 2399-2400
Author(s):  
Aisha Malik ◽  
Syed Atif Hasnain Kazmi
Keyword(s):  
Teaching Hospital ◽  
Alopecia Areata ◽  
Unknown Origin ◽  
Skin Condition ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Chronic Skin ◽  
And Gender ◽  
The University

Background: Alopecia areata (AA) is a wide spread and chronic skin condition of unknown origin. It affects the patient's quality of life. This study was designed to assess the perception of the disease in patients with AA. Aim: To determine the belief, perception and knowledge among alopecia areata patients visiting the university of Lahore teaching hospital. Study design: Descriptive cross-sectional study. Place and duration of study: Dermatology OPD, University of Lahore Teaching Hospital Lahore from September 2019 to February 2020. Methodology: This was a description cross-sectional study from September 2019 to February, 2020 and carried out in Out- Patient Department of Dermatology at University of Lahore Teaching Hospital. The study included all the patients in the age range of 20 to 42 years of age with patchy alopecia. The duration of the study was six months, total participants were 67. A questionnaire was designed for the collection of data in the data base, such as age and gender, the onset of the disease, level of education, and is based on the knowledge, beliefs and behaviors regarding alopecia areata. The data was analyzed by using the version SPSS 25. Results: Result shows that mean age of the participant’s was 29.5±4. About 77.6 participants were married and 23.4 were unmarried. The 85.6% participants of study give yes response that alopecia areata affected the people result showed 38% considered it a serious health issue. The 76.1% participants of study give yes response that alopecia areata participants have serious financial problem. About causative factors, almost half (28%) of the participants believed that germs and viruses causes Alopecia Areata. Keywords: Alopecia areata (AA), Knowledge, Perception, Belief.

Kyrle’s disease (KD): “An Update with review of literature” A Spongebob Skin pores simulation

2021 ◽  
pp. 25
Author(s):  
Keyword(s):  
Diabetes Mellitus ◽  
Heart Failure ◽  
Chronic Heart Failure ◽  
Liver Diseases ◽  
Skin Condition ◽  
Hair Follicles ◽  
Review Of Literature ◽  
Young Males ◽  
Epithelial Migration ◽  
Chronic Skin

Kyrle’s disease (KD) is a Chronic skin condition first described by Austrian pathologist Josef Kyrle in 1916. Kyrle referred to this condition as hyperkeratosis follicularis & parafollicularis in cutem penetrans. These diseases are characterized by the phenomenon of transepidermal elimination of denatured dermis an acquired form of perforating dermatosis [14]. It is characterized by keratotic crater plugs that develop in hair follicles penetrating the epidermis and extending into the dermis [4]. This trans epithelial migration and elimination of proteinaceous components is associated with systemic disorders like renal, liver diseases, chronic heart failure and diabetes mellitus. We present two case scenarios of a young Males with multiple chronic papular eruptions along with a review of literature for Kyrle’s disease (KD).

Psoriasis: Tumor Necrosis Factor –α, Interleukin 18, C Reactive Protein Polymorphism , and Osteopontin Role

2018 ◽  
Vol 1 (1) ◽  
pp. 58-62
Author(s):  
Ibrahim Abed
Keyword(s):  
Skin Condition ◽  
Chronic Inflammatory Disease ◽  
Systemic Complications ◽  
Reactive Protein ◽  
Tnf Α ◽  
Inflammatory Processes ◽  
Chronic Skin ◽  
Abnormal Lipid Metabolism ◽  
Factor Α

  Background: Psoriasis is a common chronic skin disorder with prevalence of 2.7% in Iraqi community. Many factors affect the prevalence of psoriasis which include genetic, environmental, infectious, immunological, biochemical, endocrinological and psychological. Psoriasis is a chronic inflammatory disease with unknown exact pathogenesis, which may be started as skin condition that subsequently associated with systemic complications. The recurrent proliferative inflammatory processes in subject with psoriasis may lead to abnormal lipid metabolism and associated with cardiovascular diseases. Gene polymorphisms represent either a protective or risk factors for development of psoriasis and cardiovascular disease. Aim of the Study: The aim of the present study is to provide a picture about the association between psoriasis and atherosclerosis. Objectives: To: 1. Estimate the prevalence of impending atherosclerosis in patients with psoriasis. 2. Identify the pattern of association among inflammatory markers in one hand and lipoproteins as traditional markers in another. 3. Clarify the risk assessment of atherosclerosis in patients with psoriasis using multi- biomarkers score. 4. Appraise the inter – traditional and new markers. 5. Evaluate the role of IL-18, TNF -α, osteopontin in the pathogenesis of psoriasis and atherosclerosis. 6. Illustrate the association between disease susceptibility and different gene polymorphism such as IL-18, TNF-α and CRP.  

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