scholarly journals Clinical Profile of Patients Admitted with SwineOrigin Influenza A (H1N1) Virus Infection: An Experience from a Tertiary Care Hospital

2018 ◽  
Vol 50 (01) ◽  
pp. 4-8
Author(s):  
Vikas Ratnaparkhe ◽  
2019 ◽  
Vol 6 (4) ◽  
pp. 1271
Author(s):  
Ambika Sharma ◽  
R. S. Mathur

Background: Most of the studies on swine flu H1N1 have been done during the pandemic phase. There was a sudden upsurge in virus activity in 2015 at many centers in India. The present study was designed to assess the current status and pattern of H1N1 infection. The primary objective of this study is to study the clinical profile of patients admitted with Swine-origin influenza A (H1N1) virus infection and Secondary objective is to study the clinical outcome in terms of morbidity and mortality.Methods: This was a retrospective observational study done at a tertiary care centre from March 2015 to April 2016. All admitted and confirmed cases of H1N1 swine flu infection were studied for demographic details, co-existing medical conditions and clinical presentation. Data regarding the course of disease, complications, treatments and outcomes were recorded from the clinical record.Results: Common presenting symptoms were cough and fever (95%). Common findings were fever (62.5%), tachycardia, tachypnea and crepitation on auscultation (58.5%). Associated comorbidities were Diabetes mellitus (19.5%), Chronic kidney disease (17%), immunosuppression (9.8%). Consolidation was seen in nearly half of the patients on radiological imaging. Complications noted in our patients were pneumonia (45%), respiratory failure (31%) and ARDS (14.6%). Seventeen percent of patients required non-invasive and invasive mechanical ventilation. Around 25 percent of cases, required ICU admission while two patients died during the hospital stay.Conclusions: The study emphasizes and restates the morbidities caused by H1N1 swine influenza infection as nearly half of the patients in this study experienced severe illness and complications.


2012 ◽  
Vol 4 (1) ◽  
pp. e2012002 ◽  
Author(s):  
Adnan Agha ◽  
Abdul Qader Alrawi ◽  
Abdelhaleem Bella ◽  
Mohammed S. AlAyed

Background Pandemic influenza A (H1N1) virus emerged and spread globally in the spring of 2009.  We describe the clinical features of the patients who were hospitalized with 2009 H1N1 influenza July 2009 to June 2010 in a tertiary care hospital in Khamis Mushyt, Saudi Arabia.  We analyzed the clinical and laboratory variables in order to determine predictors of poor outcome Methods We performed a prospective study in all patients who were hospitalized for at least 48 hours  and with a positive test for 2009 H1N1 virus through RT-PCR(real time polymerase chain reaction).  Their epidemiological, clinical, biochemical characteristics were collected and the hospital course of the patients with eventual outcome (discharge or death) was observed. We applied a logistic regression analysis to determine the best predictor of death.


2011 ◽  
Vol 8 (2) ◽  
Author(s):  
Turgut Teke ◽  
Ümmiye Duran ◽  
Emin Maden ◽  
Kazım Gezginç ◽  
Mehmet D Yavşan ◽  
...  

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