scholarly journals Gender differences in the longitudinal association between multilevel latent classes of chronic disease risk behaviours and body mass index in adolescents

2020 ◽  
Vol 40 (9) ◽  
pp. 259-266
Author(s):  
Nour Hammami ◽  
Ashok Chaurasia ◽  
Philip Bigelow ◽  
Scott T. Leatherdale
Keyword(s):  
Physical Activity ◽  
Body Mass Index ◽  
Substance Use ◽  
Chronic Disease ◽  
Disease Risk ◽  
Latent Classes ◽  
Risk Behaviours ◽  
Chronic Disease Risk ◽  
Gender Specific

Introduction Few studies have assessed the relationship between chronic disease risk behaviours and body mass index (BMI) in a longitudinal, sex/gender-specific context. This study used gender-specific analyses to assess the extent to which chronic disease risk behaviour latent classes are associated with BMI and weight status at follow-up. Methods Longitudinal data from 4510 students in Grades 9 to 12, tracked from 2013– 2015, who participated in the COMPASS study were used to assess gender differences in the lagged association between previously determined latent classes (of physical activity and substance use) with BMI using multilevel mixed-effects models. Our multilevel regression models assessed the association between two latent classes, active experimenters and inactive non-using youth, with BMI when stratified by gender. Results Male inactive non-substance-using youth were associated with a 0.29 higher continuous BMI (95% CI: 0.057, 0.53) and odds of overweight/obesity increased by 72% (OR = 1.72, 95% CI: 1.2, 2.4) for binary BMI at follow-up relative to active youth who experiment with substance use. No significant associations were detected in females. Conclusion Over time, physical activity has a protective role on BMI in male youth. Both substance use and physical inactivity should be addressed in obesity prevention efforts. Gender stratification in analyses is also important since females and males have different contributing factors to increases in BMI.

scholarly journals Sedentarism and chronic disease risk in COVID 19 lockdown – a scoping review

2020 ◽  
pp. 003693302094633
Author(s):  
Baskaran Chandrasekaran ◽  
Thiru Balaji Ganesan
Keyword(s):  
Mental Health ◽  
Physical Activity ◽  
Cardiovascular Disease ◽  
Chronic Disease ◽  
Sedentary Behaviour ◽  
Disease Risk ◽  
Cardiovascular Disease Risk ◽  
Chronic Disease Risk ◽  
Critical Measure ◽  
Obesity Hypertension

Background & Aims Though viewed as a critical measure to prevent the spread of the virus, a prolonged homestay may result in unfavourable sedentary behaviour and chronic disease risk. This systematic review focuses on sedentary behaviour resulting from this quarantine period which may elevate the cardiovascular disease risk, obesity, hypertension, cancer and mental health illness. Methods Evidence of breaking sedentary behaviour and global recommendations were investigated. Potential unanswered questions regarding sedentary behaviour and physical activity during lockdown were explored. Results Five systematic reviews and six prospective trials explored the effect of sedentarism affecting chronic disease through potential pathophysiological mechanisms. Sedentary behaviour especially prolonged sitting is found to be a pleiotropic risk factor with altered energy expenditure, adipogenic signalling, immunomodulation, autonomic stability and hormonal dysregulation perpetuating underlying chronic diseases such as obesity, cardiovascular disease, cancer and mental health disorders. Conclusion Breaking sitting and physical activity are found to reverse the adverse effects associated with excessive sitting during the lockdown.

Pregnancy, Physical Activity and Weight Control to Prevent Obesity and Future Chronic Disease Risk in Both Mother and Child

2015 ◽  
Vol 11 (1) ◽  
pp. 31-40 ◽  
Author(s):  
Michelle F. Mottola
Keyword(s):  
Physical Activity ◽  
Chronic Disease ◽  
Pregnant Women ◽  
Weight Control ◽  
Maternal Obesity ◽  
Healthy Lifestyle ◽  
Disease Risk ◽  
Lessons Learned ◽  
Weight Retention ◽  
Chronic Disease Risk

Maternal obesity is accelerating world-wide and may be partly due to excessive gestational weight gain (GWG) and weight retention so that women begin a subsequent pregnancy with extra weight. Excessive GWG has been linked to chronic disease risk in the mother and also to an unhealthy foetal environment with downstream consequences for offspring health with risk for childhood obesity. Weight control during pregnancy and prevention of excessive GWG is an important issue for both mother and developing child. A healthy lifestyle through healthy eating and physical activity are key to prevention. Weight management for non-pregnant individuals has been evaluated for over 30 years, and lessons learned may assist in planning interventions for preventing excessive GWG. Many systematic reviews and meta-analyses analyzing the same studies on GWG report very different results. Recently, 10 intervention trials to prevent excessive GWG were published and only 6 of them were successful. Significant association between maternal exercise and GWG guidelines were reported, however, “one size does not fit all”. The failed trials did not have extra faceto- face sessions, were educational based and adherence was <50%. Accountability, face-to-face exercise sessions, and pedometers may motivate pregnant women to increase step counts to 10,000, which, when combined with nutrition control, prevents excessive GWG. Community walking programs that include family members and children may assist pregnant women of all body mass index categories to overcome potential barriers to promote a healthy lifestyle that will benefit them and their families for weight control and prevention of future chronic disease risk.

Skeletal muscle TLR4 and TACE are associated with body fat percentage in older adults

2016 ◽  
Vol 41 (4) ◽  
pp. 446-451 ◽  
Author(s):  
Kyle L. Timmerman ◽  
Ian D. Connors ◽  
Michael A. Deal ◽  
Rachael E. Mott
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Skeletal Muscle ◽  
Chronic Disease ◽  
Body Fat ◽  
Disease Risk ◽  
Fasting Blood Glucose ◽  
Activity Level ◽  
Percent Body Fat ◽  
Chronic Disease Risk

Elevated skeletal muscle expression of toll-like receptor 4 (TLR4) has been linked to increased inflammation in clinical populations. TNFα converting enzyme (TACE), which cleaves membrane-bound TNFα (mTNFα) to its soluble (sTNFα) and more bioactive form, has been linked to chronic disease. In contrast, higher physical activity level is associated with decreased chronic disease risk and inflammation. The purpose of the present study was to examine the relationship between physical activity and skeletal muscle TLR4, TACE, and TNFα in older adults. In 26 older adults (age = 68 ± 4 years, body mass index = 26 ± 3 kg·m−2), self-reported physical activity (kcal·week−1), estimated maximal oxygen consumption, and body composition (air plethysmography) were measured. TLR4, TACE, mTNFα, and sTNFα were measured in skeletal muscle biopsies (vastus lateralis) using western blot analyses. Pearson product-moment correlations were run between variables. Significance was set at p < 0.05. Skeletal muscle TACE was directly associated with sTNFα (r = 0.53, p < 0.01). Linear regression modeling showed that mTNFα and TACE expression were predictive of sTNFα expression. No correlations were observed between physical activity and TLR4, TACE, or sTNFα. Percent body fat was directly associated with skeletal muscle TLR4 (r = 0.52, p < 0.01) and TACE (r = 0.50, p < 0.01), whereas fasting blood glucose was directly associated with TACE and sTNFα. In conclusion, we found that percent body fat was directly associated with TLR4 and TACE expression in skeletal muscle of older adults. These findings suggest that elevated skeletal muscle expression of TLR4 and TACE may contribute to the augmented inflammation and chronic disease risk observed with increased adiposity.

scholarly journals Body Mass Index, Waist Circumference, and Chronic Disease Risk Factors in Australian Adolescents

2008 ◽  
Vol 162 (6) ◽  
pp. 566 ◽  
Author(s):  
Elizabeth Denney-Wilson ◽  
Louise L. Hardy ◽  
Timothy Dobbins ◽  
Anthony D. Okely ◽  
Louise A. Baur
Keyword(s):  
Risk Factors ◽  
Body Mass Index ◽  
Chronic Disease ◽  
Waist Circumference ◽  
Body Mass ◽  
Disease Risk ◽  
Chronic Disease Risk
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