scholarly journals Approximate Bayesian Computation Applied to Model Selection and Calibration in Cell Proliferation

2021 ◽  
Author(s):  
N. Silva ◽  
B. Loiola ◽  
J. Costa ◽  
H. Orlande
Keyword(s):  
Cell Proliferation ◽  
Model Selection ◽  
Approximate Bayesian Computation ◽  
Bayesian Computation ◽  
Approximate Bayesian

scholarly journals Parameter Calibration in Crowd Simulation Models using Approximate Bayesian Computation

2020 ◽  
Vol 5 ◽  
Author(s):  
Nikolai Bode
Keyword(s):  
Model Selection ◽  
Approximate Bayesian Computation ◽  
Model Fitting ◽  
Simulation Models ◽  
Parameter Estimates ◽  
Model Parameters ◽  
Bayesian Computation ◽  
Continuous Space ◽  
Pedestrian Dynamics ◽  
Approximate Bayesian

Simulation models for pedestrian crowds are a ubiquitous tool in research and industry. It is crucial that the parameters of these models are calibrated carefully and ultimately it will be of interest to compare competing models to decide which model is best suited for a particular purpose. In this contribution, I demonstrate how Approximate Bayesian Computation (ABC), which is already a popular tool in other areas of science, can be used for model fitting and model selection in a pedestrian dynamics context. I fit two different models for pedestrian dynamics to data on a crowd passing in one direction through a bottleneck. One model describes movement in continuous-space, the other model is a cellular automaton and thus describes movement in discrete-space. In addition, I compare models to data using two metrics. The first is based on egress times and the second on the velocity of pedestrians in front of the bottleneck. My results show that while model fitting is successful, a substantial degree of uncertainty about the value of some model parameters remains after model fitting. Importantly, the choice of metric in model fitting can influence parameter estimates. Model selection is inconclusive for the egress time metric but supports the continuous-space model for the velocity-based metric. These findings show that ABC is a flexible approach and highlights the difficulties associated with model fitting and model selection for pedestrian dynamics. ABC requires many simulation runs and choosing appropriate metrics for comparing data to simulations requires careful attention. Despite this, I suggest ABC is a promising tool, because it is versatile and easily implemented for the growing number of openly available crowd simulators and data sets.

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