scholarly journals Prognostic Impact of the Length of the Distal Resection Margin in Rectosigmoid Cancer: An Analysis of the JSCCR Database between 1995 and 2004

2020 ◽  
Vol 4 (2) ◽  
pp. 59-66 ◽  
Author(s):  
Heita Ozawa ◽  
Kenjiro Kotake ◽  
Hideyuki Ike ◽  
Kenichi Sugihara
Keyword(s):  
Resection Margin ◽  
Prognostic Impact ◽  
Distal Resection Margin ◽  
Rectosigmoid Cancer

scholarly journals The risk factors of local recurrence and distant metastasis on pT1/T2N0 mid-low rectal cancer after total mesorectal excision

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
I-Li Lai ◽  
Jeng-Fu You ◽  
Yih-Jong Chern ◽  
Wen-Sy Tsai ◽  
Jy-Ming Chiang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Rectal Cancer ◽  
Local Recurrence ◽  
Distant Metastasis ◽  
Resection Margin ◽  
Radical Resection ◽  
Hazard Ratio ◽  
Low Rectal Cancer ◽  
Distal Resection Margin ◽  
Lymph Node Yield

Abstract Background Radical resection is associated with good prognosis among patients with cT1/T2Nx rectal cancer. However, still some of the patients experienced cancer recurrence following radical resection. This study tried to identify the postoperative risk factors of local recurrence and distant metastasis separately. Methods This retrospective, single-center study comprised of 279 consecutive patients from Linkou branch of Chang Gung Memorial Hospital in 2005–2016 with rectal adenocarcinoma, pT1/T2N0M0 at distance from anal verge ≤ 8cm, who received curative radical resection. Results The study included 279 patients with pT1/pT2N0 mid-low rectal cancer with median follow-up of 73.5 months. Nineteen (6.8%) patients had disease recurrence in total. Nine (3.2%) of them had local recurrence, and fourteen (5.0%) of them had distant metastasis. Distal resection margin < 0.9 (cm) (hazard ratio = 4.9, p = 0.050) was the risk factor of local recurrence. Preoperative carcinoembryonic antigen (CEA) ≥ 5 ng/mL (hazard ratio = 9.3, p = 0.0003), lymph node yield (LNY) < 14 (hazard ratio = 5.0, p = 0.006), and distal resection margin < 1.4cm (hazard ratio = 4.0, p = 0.035) were the risk factors of distant metastasis. Conclusion For patients with pT1/pT2N0 mid-low rectal cancer, current multidisciplinary treatment brings acceptable survival outcome. Insufficient distal resection margin attracted the awareness of risk factors for local recurrence and distant metastasis as a foundation for future research.

What is the optimal distal resection margin for esophageal carcinoma?

2000 ◽  
Vol 69 (1) ◽  
pp. 205-209 ◽  
Author(s):  
Alan G Casson ◽  
S.Jane Darnton ◽  
Sujata Subramanian ◽  
Louise Hiller
Keyword(s):  
Esophageal Carcinoma ◽  
Resection Margin ◽  
Distal Resection Margin

Presence of distal intramural spread after preoperative combined-modality therapy for adenocarcinoma of the rectum: What is now the appropriate distal resection margin?

Surgery ◽  
2005 ◽  
Vol 138 (4) ◽  
pp. 658-664 ◽  
Author(s):  
James J. Mezhir ◽  
Kerrington D. Smith ◽  
Alessandro Fichera ◽  
John Hart ◽  
Mitchell C. Posner ◽  
...  
Keyword(s):  
Resection Margin ◽  
Combined Modality Therapy ◽  
Distal Resection Margin ◽  
Combined Modality ◽  
Distal Intramural Spread
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