scholarly journals Smoking and tumor obstruction are risk factors for anastomotic leakage after laparoscopic anterior resection during rectal cancer treatment

2017 ◽  
Vol 1 (1) ◽  
pp. 7-14
Author(s):  
Hiroyuki Matsuzaki ◽  
Soichiro Ishihara ◽  
Kazushige Kawai ◽  
Koji Murono ◽  
Kensuke Otani ◽  
...  
Keyword(s):  
Risk Factors ◽  
Rectal Cancer ◽  
Cancer Treatment ◽  
Anastomotic Leakage ◽  
Anterior Resection ◽  
Laparoscopic Anterior Resection ◽  
Rectal Cancer Treatment

Effect of Left Colonic Artery Preservation on Anastomotic Leakage in Laparoscopic Anterior Resection for Middle and Low Rectal Cancer

2013 ◽  
Vol 37 (12) ◽  
pp. 2935-2943 ◽  
Author(s):  
Takao Hinoi ◽  
Masazumi Okajima ◽  
Manabu Shimomura ◽  
Hiroyuki Egi ◽  
Hideki Ohdan ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Anastomotic Leakage ◽  
Anterior Resection ◽  
Low Rectal Cancer ◽  
Laparoscopic Anterior Resection

scholarly journals A Retrospective Study of Risk Factors for Symptomatic Anastomotic Leakage after Laparoscopic Anterior Resection of the Rectal Cancer without a Diverting Stoma

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Zhi-Jie Wang ◽  
Qian Liu
Keyword(s):  
Risk Factors ◽  
Anastomotic Leakage ◽  
Anterior Resection ◽  
Univariate Analysis ◽  
Control Group ◽  
Primary Malignancy ◽  
Laparoscopic Anterior Resection ◽  
Diverting Stoma ◽  
Independent Risk Factors ◽  
Intraoperative Chemotherapy

Background. Anastomotic leakage (AL) is a common and devastating postoperative issue for patients who have undergone anterior resection of rectal carcinoma and can lead to increased short-term morbidity and mortality. Moreover, it might be associated with a worse oncological prognosis of tumors. This study is aimed at exploring the risk factors for symptomatic AL after laparoscopic anterior resection (LAR) for rectal tumors without a preventive diverting stoma. Materials and Methods. This case control study retrospectively reviewed the data of 496 consecutive patients who underwent LAR of the rectum without a preventive diverting stoma at the Cancer Hospital, Chinese Academy of Medical Sciences between September 2016 and September 2017. All patients were divided into an AL group and a control group based on the occurrence of postoperative symptomatic AL. Factors regarding patient-related variables, operation-related variables, and tumor-related variables were collected and assessed between the two groups through univariate and multivariate logistic regression analyses to identify independent risk factors for AL. Results. In total, 18 (3.6%) patients developed postoperative symptomatic AL. Univariate analysis showed that a synchronous primary malignancy of the left hemicolon (P=0.047), intraoperative chemotherapy (P=0.003), and level of anastomosis (P=0.033) were significantly related with AL. Multivariate analysis was subsequently performed to adjust for confounding biases and confirmed that a synchronous primary malignancy of the left hemicolon (odds ratio (OR), 12.225; 95% confidence interval (CI), 1.764-84.702; P=0.011), intraoperative chemotherapy (OR, 3.931; 95% CI, 1.334-11.583; P=0.013), and level of anastomosis (OR, 3.224; 95% CI, 1.124-9.249; P=0.030) were independent risk factors for symptomatic AL for patients who received LAR for rectal neoplasms without a preventive diverting stoma. Conclusions. Synchronous primary malignancy of the left hemicolon, intraoperative chemotherapy, and a low anastomotic level can increase the risks of postoperative symptomatic AL after LAR of the rectum without a protective diverting stoma.

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