scholarly journals Long-term assessment of anorectal function after extensive resection of the internal anal sphincter for treatment of low-lying rectal cancer near the anus

2017 ◽  
Vol 1 (1) ◽  
pp. 29-34 ◽  
Author(s):  
Hiroyuki Shiokawa ◽  
Kimihiko Funahashi ◽  
Hironori Kaneko ◽  
Tatsuo Teramoto
Keyword(s):  
Rectal Cancer ◽  
Anal Sphincter ◽  
Internal Anal Sphincter ◽  
Anorectal Function ◽  
Extensive Resection

Use of Smooth Muscle Plasty After Intersphincteric Rectal Resection to Replace a Partially Resected Internal Anal Sphincter: Long-Term Follow-Up

2009 ◽  
Vol 52 (11) ◽  
pp. 1895-1901 ◽  
Author(s):  
Osman Krand ◽  
Tunç Yalti ◽  
Gurkan Tellioglu ◽  
Melih Kara ◽  
Ibrahim Berber ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Anal Sphincter ◽  
Internal Anal Sphincter ◽  
Rectal Resection ◽  
Long Term Follow Up

Sa2044 Anal Incontinence, Sexual Complaints, and Anorectal Function in Patients With a Third Degree Anal Sphincter Rupture: Long Term Follow-up

2013 ◽  
Vol 144 (5) ◽  
pp. S-368 ◽  
Author(s):  
Arjan P. Visscher ◽  
Tze Jui Lam ◽  
Nick A. Hart ◽  
Chris J. Mulder ◽  
Richelle J. Felt-Bersma
Keyword(s):  
Anal Sphincter ◽  
Anal Incontinence ◽  
Anorectal Function ◽  
Long Term Follow Up ◽  
Sphincter Rupture

Long-term Anorectal Function after Postoperative Chemoradiotherapy in High-Risk Rectal Cancer Patients

2010 ◽  
Vol 96 (1) ◽  
pp. 34-41 ◽  
Author(s):  
Marco Lupattelli ◽  
Francesca Mascioni ◽  
Rita Bellavita ◽  
Lorena Draghini ◽  
Roberto Tarducci ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
High Risk ◽  
Cancer Patients ◽  
Anorectal Function

scholarly journals The Physiology, Pharmacology and Therapeutic Manipulation of the Internal Anal Sphincter

2002 ◽  
Vol 16 (4) ◽  
pp. 249-257 ◽  
Author(s):  
Oliver M Jones ◽  
Alison F Brading ◽  
Neil J McC Mortensen
Keyword(s):  
Anal Sphincter ◽  
Internal Anal Sphincter ◽  
Internal Sphincter ◽  
High Rate ◽  
Pharmacological Manipulation ◽  
Routes Of Administration ◽  
Sphincter Tone ◽  
Health And Disease ◽  
Medical Approach

Recent research into the physiology and pharmacology of the internal anal sphincter has elucidated the importance of this structure in health and disease. Its pharmacological manipulation for therapeutic gain has focused mainly on agents to reduce internal anal sphincter tone, a ‘chemical sphincterotomy’ that might heal chronic anal fissure. However, drugs to increase sphincter tone, and augment intermittent and appropriate relaxation are also being evaluated. The initial results with this medical approach to anorectal disease have often been disappointing, failing to match the results achievable with surgery, and many of these drugs have a high rate of side effects in the short term. However, clinical trials have yet to establish the optimum doses, dose intervals and routes of administration for many of these therapies. Furthermore, it is uncertain whether this medical approach should be applied to all patients or just to an as yet undefined subgroup. Certainly, even in the current environment of uncertainty, there is little reason not to try medical manipulation of the internal sphincter as first-line treatment. Surgery remains an option for treatment failures; patients responding to pharmacological manipulation of the internal anal sphincter are spared the long term risks of continence that are inherent in many surgical procedures on the anorectum.

scholarly journals Long-term outcome of sphincteroplasty with separate suturing of the internal and the external anal sphincter

2019 ◽  
Vol 23 (12) ◽  
pp. 1163-1172 ◽  
Author(s):  
M. R. Berg ◽  
H. Gregussen ◽  
Y. Sahlin
Keyword(s):  
Anal Sphincter ◽  
Anal Incontinence ◽  
Internal Anal Sphincter ◽  
External Anal Sphincter ◽  
Internal Sphincter ◽  
Long Term Outcome ◽  
Obstetric Injury ◽  
Endoanal Sonography

Abstract Background Sphincteroplasty is one of the treatment options for anal incontinence following obstetric injury. The aim of the study was to evaluate the long-term effect of sphincteroplasty with separate suturing of the internal and the external anal sphincter on anal continence. Methods A retrospective study was conducted on women who had sphincteroplasty for treatment of anal incontinence following obstetric injury. Women operated between January 1, 2011 and December 31, 2014 at Sykehuset Innlandet Hospital Trust Hamar, were invited to answer a questionnaire and participate in a clinical examination, including endoanal sonography. Results 111 (86.7%) women participated. Median postoperative follow-up was 44.5 months, and 63.8% of the participants experienced an improvement of at least three points in the St. Mark’s incontinence score. Fecal urgency and daily fecal leakage persisted in 39.4% and 6.4% of the participants, respectively. The internal anal sphincter improvement persisted in 61.8% of the participants, and there was a median reduction of their St. Mark’s score of 6.0 points between the preoperative value and the value at long-term follow-up. There was no significant change in the St. Mark’s score of patients with persistent dehiscence of the internal anal sphincter. Conclusions Sphincteroplasty, with separate suturing of the internal sphincter resulted in continence for stool maintained for at least 3 years in the majority of the patients, while there was an improvement in continence in nearly two-thirds.

Intersphincteric resection with excision of internal anal sphincter for conservative treatment of very low rectal cancer

1999 ◽  
Vol 42 (9) ◽  
pp. 1168-1175 ◽  
Author(s):  
Eric Rullier ◽  
Frank Zerbib ◽  
Christophe Laurent ◽  
Catherine Bonnel ◽  
Michel Caudry ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Conservative Treatment ◽  
Anal Sphincter ◽  
Internal Anal Sphincter ◽  
Intersphincteric Resection ◽  
Low Rectal Cancer ◽  
Very Low Rectal Cancer
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