scholarly journals A comparative study on ABO blood group and fertility hormones in infertile women in Calabar, Southern Nigeria

2018 ◽  
Vol 2 (2) ◽  
pp. 19-24
Author(s):  
Uwem Okon Akpan ◽  
Iya Eze Bassey ◽  
Nnenna Nkiruka Nwatu ◽  
Sunday Jeremiah Offor
Keyword(s):  
Blood Group ◽  
Strong Association ◽  
Blood Groups ◽  
Female Infertility ◽  
Enzyme Linked Immunosorbent Assay ◽  
P Value ◽  
Abo Blood Group ◽  
Blood Group System ◽  
Significant Difference ◽  
The Mean

Infertility, a disorder of the reproductive system, is commonly linked to hormonal, pituitary, cervical, uterine, immunological or psychological factors. Besides these factors, it can also be idiopathic or unexplained. Hence, there is a need for more research to unravel the causes of the unexplained infertility. This work aimed at finding out whether there is any relationship between ABO blood group system and female infertility. The study design was cross-sectional. Three hundred women between 18 and 40 years attending fertility clinic at the University of Calabar Teaching Hospital, Calabar between 2011 and 2012 were recruited for this study. Serum progesterone, prolactin, follicle stimulating hormone (FSH), luteinizing hormone (LH) and estradiol were determined using Enzyme linked immunosorbent assay (ELISA) while ABO blood grouping was determined using the tube method. Statistical analysis was done using SPSS version 18. The confidence level was set at 95% where p-value less than 0.05 was considered statistically significant. The mean age of the women was 30.65 ± 5.47 years and the percentage distributions of the blood groups among the women were as follows: 24% A, 12% B, 4% AB and 60% O. The mean FSH levels of blood groups A and O individuals were significantly higher (p<0.05) than that of groups B. However, there was no significant difference (p>0.05) in the mean levels of progesterone, prolactin, LH and estradiol in the respective groups. From this study, 38% of the population had increased levels of progesterone, 58% and 18.7% had elevated prolactin and FSH levels respectively while 11.33% and 43.3% had reduced levels of LH and estradiol levels respectively. Though, there was high prevalence of hyperprolactinemia observed in this study, there was no strong association between ABO blood group and female infertility but, the increased FSH levels observed in blood groups A and O may be a potential link between blood group and infertility and therefore may be beneficial for further study.

scholarly journals Comparison of blood group based on bleeding manifestation in pediatric- dengue cases

2018 ◽  
Vol 1 ◽  
pp. 00001
Author(s):  
Amrina Rosyada ◽  
Sulistiawati Sulistiawati ◽  
Dominicus Husada ◽  
Jusak Nugraha
Keyword(s):  
Blood Coagulation ◽  
Blood Group ◽  
Coagulation Factor ◽  
Bleeding Risk ◽  
P Value ◽  
Abo Blood Group ◽  
Blood Group System ◽  
Cross Sectional ◽  
Significant Difference ◽  
Bleeding Manifestation

<p class="Abstract">Bleeding manifestation in dengue cases presents due to the impairment of blood homeostasis. Previous studies mentioned that blood group O have higher bleeding risk because of lower blood coagulation von Willebran Factor (vWF) and factor VIII (FVIII) compared to non-O blood groups. This study was aiming to identify the comparison of blood group based on bleeding manifestation in pediatric dengue cases. The method used was a cross-sectional study with consecutive sampling in Pediatric Inpatient Ward Dr. Soetomo General Hospital, Surabaya, Indonesia, during March–September 2016. The study involved 86 dengue pediatric patients with 52 patients that fulfilled the inclusive criteria. The blood group, diagnosis, and the presence of bleeding manifestation data were collected from medical records and analyzed using chi-square test with p-value <0.05 and confidence interval 95 %. Blood group was divided based on ABO blood group system and based on blood group O and non-O. The results showed that there was no significant difference between ABO blood group based on the presence of bleeding manifestation (p = 0.579), and there was no significant difference between blood group O and non-O based on the presence of bleeding manifestation (p = 0.600). In this study, there was no significant difference between blood group based on bleeding manifestation in pediatric dengue cases. The previous bleeding risk theory based on blood coagulation factor was not proven based on this research.<o:p></o:p></p>

scholarly journals ABO Blood Group System: Its Association with Anthropometric Indices among Young Adults of Yoruba Ethnicity

2019 ◽  
pp. 1-7
Author(s):  
M. A. Asafa ◽  
O. Ogunlade ◽  
R. A. Bolarinwa ◽  
L. A. Bisiriyu ◽  
O. A. Eluwole ◽  
...  
Keyword(s):  
Young Adults ◽  
Blood Group ◽  
Blood Groups ◽  
Abo Blood Group ◽  
Blood Group System ◽  
Anthropometric Indices ◽  
Blood Group A ◽  
Group A ◽  
The Mean ◽  
Apparently Healthy

Introduction: The ABO blood group system is unique in immunology and haematology because it is the only system in which antibodies are consistently and predictably present in the serum of normal individuals whose red cells lack the antigens. Several epidemiological studies have reported that the distribution of different ABO blood groups vary markedly among the populations of different geographical areas reflecting racial differences. Aims: The aim of this study was to determine the association between ABO blood group and anthropometric indices among apparently healthy young adults of Yoruba ethnicity. Study Design: This is a cross-sectional descriptive study. Place and Duration of Study: The study was carried out at Department of Physiological Sciences and University Health Centre, Obafemi Awolowo University, Ile-Ife between May 2016 to June 2017. Methodology: Eighty apparently healthy young adults who were purposely selected participated in the study after screening for the ABO blood groups following the standard protocol. They were divided into four equal groups; 20 in each of blood groups A, B, AB and O who were age- and sex - matched. The weight (kg) and height (cm) of the participants were measured following standard protocol. Body mass index (BMI) and body surface area (BSA) were estimated from weight and height using Quetelex and Mosteller formulae respectively. Chi-square was used to compare grouped data while the comparison of means of parameters among the four blood groups was done using Analysis of Variance (ANOVA). A p-value of < 0.05 was taken statistically significant. Results: Out of the total 80 participants, 15% were males. The mean ± SD of height(m) of participants with blood groups A, B, O and AB were 1.65 ± 0.06, 1.63 ± 0.08, 1.62 ± 0.08 and 1.63 ± 0.08 (F= 0.349, p= 0.790) respectively. The mean ± SD of weight(kg) of the participants with blood group A,B, O and AB were 56.15 ± 8.71, 56.00 ± 11.21, 57.10 ± 12.73 and 58.05 ± 10.35 (F= 0.154, p= 0.927) respectively. The mean ± SD of BMI in kg/m2 for blood groups A, B, O and AB were 20.74 ± 3.22, 20.86 ± 2.91, 21.79 ± 5.10 and 21.91 ± 4.21 (F= 0.472, p= 0.703) respectively while the mean ± SD of BSA (m2) for blood group A, B, O and AB were 1.60 ± 0.12, 1.59 ± 0.19, 1.60 ± 0.18 and 1.62 ± 0.15 (F= 0.098, p= 0.961) respectively. Conclusion: AB Blood group may be predisposed to metabolic syndrome due to the higher mean of weight, BSA and BMI found in this group.

scholarly journals Association of Blood Groups with Oral Submucous Fibrosis and if any of the Blood Group is Related with an Increased Risk for Oral Submucous Fibrosis

2021 ◽  
Vol 15 (10) ◽  
pp. 2776-2778
Author(s):  
Sobia Siddique ◽  
Syed Muhammad Razi Zaidi ◽  
Shahida Maqbool ◽  
Madiha Insha ◽  
Muhammad Abul Hasan Ali ◽  
...  
Keyword(s):  
Blood Group ◽  
Oral Submucous Fibrosis ◽  
Malignant Lesion ◽  
Oral Pathology ◽  
Blood Groups ◽  
P Value ◽  
Blood Group System ◽  
Increased Risk ◽  
Submucous Fibrosis ◽  
B Blood Group

Objective: To assess any association of blood groups with oral submucous fibrosis and if any of the blood group is related with an increased risk for oral submucous fibrosis. Study Design: Comparative study Place and Duration of Study: Department Of Oral Pathology, Fatima Jinnah Dental College & Hospital Karachi, Pakistan from Jan to Dec 2018. Patients and Methods: Total 100 patients were enrolled in the study in which half were cases where oral sub mucous fibrosis had been diagnosed clinically while remaining half were the controls that were involved in the habit of using tobacco/nuts but had no oral pre malignant lesion. For investigation of blood, samples of blood were taken from both the groups. Odd ration and chi-square test was used to analyze data. A p-value of <0.05 was considered statistically significant. Results: Majority of the individuals in experimental group had “B” blood group followed by “O” “AB” and “A” blood groups. Conclusion: This study showed that ABO blood groups have considerable relation with oral submucous fibrosis. Individuals having “B” blood group had 2.18 times increased tendency of having oral submucous fibrosis in contrast with patients who belong to any other blood group. Keywords: ABO blood group system, Oral Submucous fibrosis, Oral lesions, Oral Squamous Cell Carcinoma

scholarly journals Association of Pre-hypertension with blood groups in young population.

2019 ◽  
Vol 26 (11) ◽  
pp. 1820-1824
Author(s):  
Benash Altaf ◽  
Shireen Jawed ◽  
Fakiha Behram ◽  
Zeeshan Ali Khan ◽  
Shakeela Naz
Keyword(s):  
Blood Group ◽  
Demographic Data ◽  
Cross Sectional Study ◽  
Blood Groups ◽  
P Value ◽  
Continuous Variables ◽  
Cross Sectional ◽  
Blood Group A ◽  
Significant Difference ◽  
Group A

Objectives: Pakistan has highest mortality rate due to hypertension and its complications. Hypertension is a squealed of Pre- hypertension which is believed to start at adolescent and continue to adulthood. Association of blood group with hypertension is evident but still hypothesized. This study aims to find the frequency of prehypertension and its association with blood group. Study Design: Cross sectional study. Setting:  Aziz Fatimah Medical and Dental College, Faisalabad. Period: 15 March’18 to 15 Sep’18. Material and Methods:  It was comprised of in comprised of 100 MBBS students. Demographic data including age, weight, height, waist and hip circumference, and BMI was determined. Blood group was determined with help of conventional slide method. Blood pressure was measured by auscultatory method. Data was analyzed by using SPSS 21. Continuous variables are given in mean and standard deviation. Categorical data was given in frequency and percentages. P value≤ 0.05 is taken as significant. Results: Out of 100 participants most common blood group was group ‘O’ (43%) followed by B (35 %) and AB (13%) and A (9%).36% of total population was pre-hypertensive and 64% were normotensive. Prehypertension is most commonly found in blood group ‘A’ (77%) followed by blood group ‘O’ (46.5%). Significant difference was found in means of SBP (p value= 0.001*) and DBP (p value= 0.000*) among the various blood groups. Conclusion: Most common blood group in studied population was ‘O’ although hypertension was most commonly observed in blood group A followed by ‘O’.

Is type 1 diabetes mellitus associated with ABO & Rh blood groups? A cross-sectional study

2022 ◽  
Author(s):  
Mahtab Ordooei ◽  
Nasim Namiranian ◽  
Saeedeh Jam-Ashkezari ◽  
Hadi Jalali ◽  
Azam Golzar
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Blood Group ◽  
Cross Sectional Study ◽  
Blood Groups ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Mean

Background: This study was conducted to determine whether type 1 diabetes mellitus (T1DM) is associated with ABO & Rhesus (Rh) blood groups. Materials and Methods: This analytical cross sectional study was carried out on 77 patients suffering from T1DM and 96 healthy children less than 18 years old referring to Yazd Diabetes Research Center from April 2018 to May 2019. The ABO blood group and Rh factor in both groups were determined. Fasting blood sugar (FBS) and hemoglobin A1C (HbA1c) were measured at baseline, 12 weeks, and 24 weeks in these patients, and the mean of FBS and HbA1C in three-time assessments were considered as the FBS and HbA1C variables. The statistical analysis was performed by SPSS software version 22. Results: About 46.8% in T1DM and 36.5% in the control groups were male. There was a significant difference between groups regarding blood groups (p-value: 0.042). Although the frequency of B+ was 33.8% and 19.8% in the T1DM and controls, respectively, AB+ and O+ were more prevalent in the controls. The mean of FBS was significantly different between groups (p-value: 0.023). Conclusions: The findings revealed that patients with blood group B are more likely to develop T1DM whereas those with blood group O showed a lower tendency towards diabetes.

scholarly journals Association of ABO Blood Group and Body Mass Index: A Cross-Sectional Study from a Ghanaian Population

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Samuel Smith ◽  
Isaac Okai ◽  
Chrissie Stansie Abaidoo ◽  
Emmanuel Acheampong
Keyword(s):  
Body Mass Index ◽  
Blood Group ◽  
Body Mass ◽  
Cross Sectional Study ◽  
Blood Groups ◽  
Blood Type ◽  
Abo Blood Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Significant Difference

ABO blood group and body mass index (BMI) have individually been appraised as risk factors for certain diseases. From statistical perspective, it may be important to examine the relationship between the ABO blood antigen and BMI. This cross-sectional study involved 412 participants aged 18 to 46 at the Kwame Nkrumah University of Science and Technology (KNUST), Kumasi. Weight and height of participants were measured for BMI calculation; blood group determination was done using antisera. Blood group O was the most prevalent (51.2%), while Rhesus-positive individuals constituted 90.3%. 6.3% of the participants were obese, while 18.7% were overweight. There was significant (p=0.006) higher prevalence of obesity in females (10.3%) than in males (3.4%). The study did not observe any significant difference by association of ABO blood group with gender (p=0.973), BMI (p=0.307), or Rhesus status (p=0.723). Regarding gender (p=0.400) and BMI (p=0.197), no statistically significant difference was observed between Rhesus blood groups. The prevalence of overweight, obesity, blood type O, and rhesus positive observed among students in this study is largely similar to what has been reported in published studies in Ghana and from other countries. Overweight and obesity were not associated with ABO blood groups or Rhesus in this study.

scholarly journals Correlation between CT chest severity score (CT-SS) and ABO blood group system in Egyptian patients with COVID-19

2021 ◽  
Vol 52 (1) ◽  
Author(s):  
Mohamed G. Mansour ◽  
Ahmed S. Abdelrahman ◽  
Emad H. Abdeldayem
Keyword(s):  
Blood Group ◽  
Severity Score ◽  
Abo Blood Group ◽  
Blood Group System ◽  
Moderate Severity ◽  
Group System ◽  
Blood Group A ◽  
Egyptian Patients ◽  
Group A ◽  
The Mean

Abstract Background The 2019 coronavirus disease (COVID-19) has become a global health crisis. CT chest is considered as an important investigation for early diagnosis as well as assessment of severity of COVID-19 pneumonia. Several articles reported that there is a correlation between ABO blood group system and susceptibility as well as prognosis of the disease. In our study we correlated the CT severity score (CT-SS) and the ABO blood group in patients with COVID-19 infection. This study involved 547 symptomatic patients with pathologically proven COVID-19 infection (positive PCR); non contrast CT chest was done for all cases and CT severity score (CT-SS) was calculated followed by its correlation with the patients’ ABO blood group. Aim of the work was to evaluate the relation between CT-SS and the ABO blood groups in Egyptian patients with COVID-19 infection. Results The mean CT-SS in patients with blood group A patients (n = 153; 28%) was 13.7 (moderate severity), while in patients with blood group O (n = 227; 41.5%) the mean CT-SS was 6.7 (mild severity). In blood group B patients (n = 139; 25.4%) the mean CT-SS was 9.1 (mild to moderate severity) and in blood group AB patients (n = 28; 5.1%) the mean CT-SS was 9.7 (mild to moderate severity). Conclusion COVID-19 patients with blood group A are more prone to aggressive CT findings (higher CT-SS) and consequently may be susceptible to increased risk of mortality compared to the patients with other blood groups; however, patients with blood group O are suggested to have the least CT-SS and appear to be relatively protected.

scholarly journals Prevalence of ABO and Rh blood groups and their association with Transfusion-Transmissible Infections (TTIs) among Blood Donors in Islamabad, Pakistan

2021 ◽  
Vol 3 (4) ◽  
Author(s):  
Muhammad Yousaf Khan ◽  
Farwa Sijjeel ◽  
Ahmareen Khalid ◽  
Rukhshan Khurshid ◽  
Umm E Habiba ◽  
...  
Keyword(s):  
Viral Infection ◽  
Blood Group ◽  
Blood Donors ◽  
Blood Groups ◽  
Abo Blood Group ◽  
Blood Group System ◽  
Syphilis Infection ◽  
Group System ◽  
Group A ◽  
Group B

Certain Rh positive blood groups showed a link between the ABO blood grouping and susceptibility to some infectious ailments. Study was carried out to find the association of ABO Blood Group System / Rh type with different viral infection. A retrospective observational study was carried in 7631 blood donors to find the association of ABO Blood Group System / Rh type with viral infection due to hepatitis B virus, hepatitis C virus, human immunodeficiency virus and Syphilis. Data of the study indicateF that the highest incidence of blood group in blood donor was B followed by O, A and AB. The incidence of HBsAg +ve, HCV Ab +ve and infection of Syphilis was also highest in donor with blood group B followed by O, A and AB. Blood group A were more susceptible to HIV Ab +ve followed by blood group B, O and AB. The group B donors had the greatest risk of viral infection with HBV, HCV, HIV, and Syphilis; followed by the groups O, A, and AB. Donors in group AB had the lowest incidence rate of all viral infection. The study revealed that blood group B is most prevalent among donors, followed by blood groups O, A, and AB. On the other side, the rate of HBV, HCV, HIV, and Syphilis infection was greatest among group B donors, followed by group O, group A, and group AB. Copyright(c) The Authors

scholarly journals ABO blood group system and occurrence of ischemic stroke

2021 ◽  
Author(s):  
Rafaella Chiodini LOTZ ◽  
Carolina da Silveira WELTER ◽  
Silvia Aparecida RAMOS ◽  
Leslie Ecker FERREIRA ◽  
Norberto Luiz CABRAL ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Blood Group ◽  
Cerebrovascular Diseases ◽  
Blood Groups ◽  
Blood Type ◽  
Control Group ◽  
Abo Blood Group ◽  
Blood Group System ◽  
Abo Blood Groups ◽  
Group System

ABSTRACT Background: Ischemic stroke (IS) is a multifactorial disease that presents high rates of morbimortality in Brazil. Several studies proved that there is a link between the ABO blood group system and the occurrence of thrombotic events. Nonetheless, its association with IS is not well established. Objective: For that reason, the purpose hereof was to investigate the relation between the ABO blood groups and the occurrence of IS in a Brazilian cohort of cerebrovascular diseases. Methods: Five hundred and twenty-nine subjects were included over 12 months, from which 275 presented an IS episode and 254 composed the control group. Blood samples were drawn for direct and reverse serotyping. The control and IS groups were compared regarding the traditional risk factors and the distribution of the ABO blood groups. Results: The IS group presented a higher prevalence of systemic arterial hypertension (SAH), diabetes mellitus, smoking habits, family history, cardiopathy, and sedentary lifestyle in comparison with the control group. The AB blood type prevailed among the patients (5.1 vs. 1.6%; p<0.05) and this group had more SAH cases in comparison with the O type group (92.9 vs. 67.3%; p<0.05). Conclusions: Our results suggest that the occurrence of IS is more frequent among patients of the AB blood type.

scholarly journals Relationship of Blood Group Type and SARS-CoV-2 Infection: Experience in A Peripheral Military Hospital

2021 ◽  
Vol 39 (2) ◽  
pp. 94-99
Author(s):  
Md Soleman Badsha ◽  
Md Mizanur Rahman Khan ◽  
SM Belal Uddin ◽  
Kamrun Nesa
Keyword(s):  
Blood Group ◽  
Statistical Significance ◽  
Blood Groups ◽  
Military Hospital ◽  
Control Group ◽  
P Value ◽  
Percentage Distribution ◽  
Blood Group A ◽  
Significant Difference ◽  
Group A

Introduction: Clinical studies have shown that advanced age and chronic diseases increase the risk of infection. Different studies have found blood groups are also a determining factor of severity. However, in Bangladesh it is yet to have any clinical pattern in this respect. The aim of this study is to find out whether there exists a relationship between the blood groups of the patients and risk of SARS-CoV-2 infection. Methods: The study is a retrospective cohort study. It included all hospitalized RT-PCR confirmed COVID-19 patients in Combined Military Hospital (CMH) Barishal. We included both genders and people who are older than 14 years of age. The study was conducted during the period between 4th June and 3rd August, 2020. In this period total 556 individuals reported and tested for SARS-CoV-2 where COVID +ve patients are served as patient group and COVID –ve patients are served as the controls. Results: Our sample consists of 185 patients; we found a percentage distribution of 34.6%, 39.5%, 5.4%, and 20.54% for blood groups A, B, AB and O, respectively. Blood group A was statistically significantly more frequent among those infected with COVID-19 compared to controls (34.6% vs. 21.83%, p-value 0.045 (<0.05); OR: 1.894).On the other hand, the frequency of blood group O was significantly lower in the COVID-19 patients, compared to the control group (20.54% vs 32.88%, p-value0.049 (<0.05); OR: 0.528). Although there was a higher percentage distribution of the B blood group among COVID-19 patients as compared to the control groups, this difference did not reach statistical significance. Also, there was no significant difference in the risk of COVID-19 in blood group AB with a distribution of 6.2% in control group, and5.4% in COVID-19 patients. Conclusion: The results of the present study suggest that the blood group A might have a role in increased susceptibility to the COVID-19 infection and the blood group O might be somewhat protective. J Bangladesh Coll Phys Surg 2021; 39(2): 94-99

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