Towards a personal at-home lab for motion video tracking in patients with Parkinson's disease

2017 ◽  
Author(s):  
Alexander Yu. Meigal ◽  
Kirill S. Prokhorov ◽  
Nikita A. Bazhenov ◽  
Liudmila I. Gerasimova-Meigal ◽  
Dmitry G. Korzun
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Video Tracking ◽  
Motion Video ◽  
At Home

scholarly journals Limb and trunk accelerometer data collected with wearable sensors from subjects with Parkinson’s disease

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Gloria Vergara-Diaz ◽  
Jean-Francois Daneault ◽  
Federico Parisi ◽  
Chen Admati ◽  
Christina Alfonso ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Symptom Severity ◽  
Wearable Sensors ◽  
Motor Fluctuations ◽  
Sensor Data ◽  
Accelerometer Data ◽  
Motor Tasks ◽  
Specific Symptom ◽  
At Home

AbstractParkinson’s disease (PD) is a neurodegenerative disorder characterized by motor and non-motor symptoms. Dyskinesia and motor fluctuations are complications of PD medications. An objective measure of on/off time with/without dyskinesia has been sought for some time because it would facilitate the titration of medications. The objective of the dataset herein presented is to assess if wearable sensor data can be used to generate accurate estimates of limb-specific symptom severity. Nineteen subjects with PD experiencing motor fluctuations were asked to wear a total of five wearable sensors on both forearms and shanks, as well as on the lower back. Accelerometer data was collected for four days, including two laboratory visits lasting 3 to 4 hours each while the remainder of the time was spent at home and in the community. During the laboratory visits, subjects performed a battery of motor tasks while clinicians rated limb-specific symptom severity. At home, subjects were instructed to use a smartphone app that guided the periodic performance of a set of motor tasks.

scholarly journals Design of a virtual longitudinal observational study in Parkinson’s disease (AT‐HOME PD)

2020 ◽  
Author(s):  
Ruth B. Schneider ◽  
Larsson Omberg ◽  
Eric A. Macklin ◽  
Margaret Daeschler ◽  
Lauren Bataille ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Observational Study ◽  
Longitudinal Observational Study ◽  
At Home

scholarly journals Validity and Responsiveness of At-Home Touch Screen Assessments in Advanced Parkinson's Disease

2015 ◽  
Vol 19 (6) ◽  
pp. 1829-1834 ◽  
Author(s):  
Mevludin Memedi ◽  
Dag Nyholm ◽  
Anders Johansson ◽  
Sven Palhagen ◽  
Thomas Willows ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Touch Screen ◽  
Advanced Parkinson’S Disease ◽  
At Home

scholarly journals Assessing mobility at home in people with early Parkinson’s disease using an instrumented Timed Up and Go test

2011 ◽  
Vol 17 (4) ◽  
pp. 277-280 ◽  
Author(s):  
Cris Zampieri ◽  
Arash Salarian ◽  
Patricia Carlson-Kuhta ◽  
John G. Nutt ◽  
Fay B. Horak
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Timed Up And Go ◽  
Early Parkinson’S Disease ◽  
At Home

scholarly journals Effect of Acute Levodopa Up-Titration on Blood Pressure in Patients With Early Stage Parkinson’s Disease: Results of a Levodopa Challenge Test

2022 ◽  
Vol 13 ◽  
Author(s):  
Xiaoqin He ◽  
Chengjun Mo ◽  
Yi Zhang ◽  
Ying Cai ◽  
Xiaodong Yang ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Early Stage ◽  
Challenge Test ◽  
Drug Uptake ◽  
Induced Hypotension ◽  
Before And After ◽  
Standing Up ◽  
At Home

Objective: Levodopa up-titration is the primary therapeutic strategy as the Parkinson’s disease (PD) progresses. However, the effects of levodopa up-titration on blood pressure (BP) are inconclusive. This study aimed to investigate the effect of acute levodopa up-titration simulated by levodopa challenge test (LCT) on BP in patients with early stage PD.Methods: We monitored BP in 52 patients with early stage PD using a standardized standing test. BP was assessed in supine position after 10 min of rest and at 1 and 3 min after standing up. BP was measured in the “off-state” and the best “on-state” during LCT in the morning at hospital. In another day, “off-state” and the best “on-state” BP was measured before and after anti-PD drug uptake in the morning at home. Demographic and clinical features of the patients were evaluated and analyzed.Results: In the LCT, the prevalence of OH in the “off-state” and the best “on-state” was 11.5 and 13.5%, respectively. Additionally, the OH in the best “on-state” was associated with OH in the “off-state” and monoamine oxidase B inhibitor use. Although 38 (73.1%) patients experienced levodopa-induced hypotension during the LCT, no risk factors were identified. While BP reductions were observed after taking anti-PD drugs at home, no further reduction was seen during acute levodopa up-titration simulated by the LCT.Conclusion: Our results demonstrate that acute levodopa up-titration does not exacerbate BP reduction induced by anti-PD drugs at home. BP monitoring is critical for the management of patients with PD.

Assessment of Parkinson’s Disease At-home Using a Natural Interface Based System

2019 ◽  
pp. 417-427
Author(s):  
Claudia Ferraris ◽  
Roberto Nerino ◽  
Antonio Chimienti ◽  
Giuseppe Pettiti ◽  
Corrado Azzaro ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Natural Interface ◽  
At Home

scholarly journals Testing objective measures of motor impairment in early Parkinson's disease: Feasibility study of an at-home testing device

2009 ◽  
Vol 24 (4) ◽  
pp. 551-556 ◽  
Author(s):  
Christopher G. Goetz ◽  
Glenn T. Stebbins ◽  
David Wolff ◽  
William DeLeeuw ◽  
Helen Bronte-Stewart ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Feasibility Study ◽  
Motor Impairment ◽  
Objective Measures ◽  
Testing Device ◽  
Home Testing ◽  
Early Parkinson’S Disease ◽  
At Home
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