scholarly journals Enamel Protein Regulation and Dental and Periodontal Physiopathology in Msx2 Mutant Mice

2010 ◽  
Vol 177 (5) ◽  
pp. 2516-2526 ◽  
Author(s):  
Muriel Molla ◽  
Vianney Descroix ◽  
Muhanad Aïoub ◽  
Stéphane Simon ◽  
Beatriz Castañeda ◽  
...  
Keyword(s):  
Mutant Mice ◽  
Protein Regulation ◽  
Enamel Protein

New insights into heparan sulphate biosynthesis from the study of mutant mice

2002 ◽  
Vol 69 ◽  
pp. 47-57 ◽  
Author(s):  
Catherine L. R. Merry ◽  
John T. Gallagher
Keyword(s):  
Growth Factors ◽  
Biosynthetic Pathway ◽  
Heparan Sulphate ◽  
Mutant Mice ◽  
Gene Products ◽  
Multiple Gene ◽  
Adhesion Proteins ◽  
Ligand Interactions

Heparan sulphate (HS) is an essential co-receptor for a number of growth factors, morphogens and adhesion proteins. The biosynthetic modifications involved in the generation of a mature HS chain may determine the strength and outcome of HS–ligand interactions. These modifications are catalysed by a complex family of enzymes, some of which occur as multiple gene products. Various mutant mice have now been generated, which lack the function of isolated components of the HS biosynthetic pathway. In this discussion, we outline the key findings of these studies, and use them to put into context our own work concerning the structure of the HS generated by the Hs2st-/- mice.

Author response for "Protection from EAE in DOCK8 mutant mice occurs despite increased Th17 cell frequencies in the periphery"

2018 ◽  
Author(s):  
Alicia S. Wilson ◽  
Hsei Di Law ◽  
Christiane B. Knobbe‐Thomsen ◽  
Conor J. Kearney ◽  
Jane Oliaro ◽  
...  
Keyword(s):  
Th17 Cell ◽  
Mutant Mice ◽  
Author Response
Sign in / Sign up

Export Citation Format

Share Document