scholarly journals Pregnancy Outcomes in Young Women With Youth-Onset Type 2 Diabetes Followed in the TODAY Study

Diabetes Care ◽  
2021 ◽  
pp. dc211071
Author(s):  
Keyword(s):  
Type 2 Diabetes ◽  
Young Women ◽  
Pregnancy Outcomes ◽  
Onset Type

scholarly journals Pregnancy Outcomes in Young Women With Youth-Onset Type 2 Diabetes Followed in the TODAY Study

2021 ◽  
Author(s):  
Jeanie B. Tryggestad ◽  
Megan M. Kelsey ◽  
Kimberly L. Drews ◽  
Steven D. Chernausek ◽  
Elia N. Escaname ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Young Women ◽  
Gestational Age ◽  
Pregnancy Outcomes ◽  
Self Report ◽  
Large For Gestational Age ◽  
Chronic Hypertension ◽  
Onset Type ◽  
Contraception Use

<b>Objective:</b> To assess pregnancy outcomes in young women with youth-onset type 2 diabetes followed in the TODAY study. <p><em><b>Research Design and Methods:</b></em><em> </em>Pregnancy information (outcome, any maternal or fetal complications) was obtained from the female participants by self-report. Additionally, medical records for the pregnancy and the child’s neonatal course were obtained with data abstracted into standardized forms.<em></em></p> <p><b>Results:</b> Over a maximum of 15 years, 260 pregnancies were reported by 141 women (age 21.5 years ± 3.2 years, BMI 35.6 ± 7.2 kg/m<sup>2</sup>, diabetes duration 8.1 ± 3.2 years). Contraception use prior to pregnancy reported by 13.5% of the women. Complications were reported by 65% of the women during their pregnancy. Pregnancy loss was observed in 25.3% and preterm birth in 32.6% of pregnancies. HbA1c ≥ 8% was observed in 31.9% of the pregnancies and 35% of the pregnancies were complicated by chronic hypertension. Nephropathy prior to pregnancy was observed in 25% of the women. In the offspring, 7.8% were classified as small for gestational age, 26.8% large for gestational age, and 17.9% in the macrosomic range.</p> <b>Conclusion:</b> Based on observations from the TODAY cohort, young women with pre-gestational, youth-onset type 2 diabetes had very high rates of maternal complications stemming from significant socioeconomic disadvantage. The substantial maternal and infant complications seen in these young moms could potentially be avoided with improved contraception rates and reproductive planning.

scholarly journals Pregnancy Outcomes in Young Women With Youth-Onset Type 2 Diabetes Followed in the TODAY Study

2021 ◽  
Author(s):  
Jeanie B. Tryggestad ◽  
Megan M. Kelsey ◽  
Kimberly L. Drews ◽  
Steven D. Chernausek ◽  
Elia N. Escaname ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Young Women ◽  
Gestational Age ◽  
Pregnancy Outcomes ◽  
Self Report ◽  
Large For Gestational Age ◽  
Chronic Hypertension ◽  
Onset Type ◽  
Contraception Use

<b>Objective:</b> To assess pregnancy outcomes in young women with youth-onset type 2 diabetes followed in the TODAY study. <p><em><b>Research Design and Methods:</b></em><em> </em>Pregnancy information (outcome, any maternal or fetal complications) was obtained from the female participants by self-report. Additionally, medical records for the pregnancy and the child’s neonatal course were obtained with data abstracted into standardized forms.<em></em></p> <p><b>Results:</b> Over a maximum of 15 years, 260 pregnancies were reported by 141 women (age 21.5 years ± 3.2 years, BMI 35.6 ± 7.2 kg/m<sup>2</sup>, diabetes duration 8.1 ± 3.2 years). Contraception use prior to pregnancy reported by 13.5% of the women. Complications were reported by 65% of the women during their pregnancy. Pregnancy loss was observed in 25.3% and preterm birth in 32.6% of pregnancies. HbA1c ≥ 8% was observed in 31.9% of the pregnancies and 35% of the pregnancies were complicated by chronic hypertension. Nephropathy prior to pregnancy was observed in 25% of the women. In the offspring, 7.8% were classified as small for gestational age, 26.8% large for gestational age, and 17.9% in the macrosomic range.</p> <b>Conclusion:</b> Based on observations from the TODAY cohort, young women with pre-gestational, youth-onset type 2 diabetes had very high rates of maternal complications stemming from significant socioeconomic disadvantage. The substantial maternal and infant complications seen in these young moms could potentially be avoided with improved contraception rates and reproductive planning.

1780-P: Differential Effects of Medications and Gastric Banding on OGTT-Modeled Measures of ß-Cell Function in Adults with IGT or Recent-Onset Type 2 Diabetes (T2D)

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 1780-P
Author(s):  
KRISTINA UTZSCHNEIDER ◽  
LAURE EL GHORMLI ◽  
SUSAN SAM ◽  
DAVID A. EHRMANN ◽  
KIEREN J. MATHER ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Gastric Banding ◽  
Cell Function ◽  
Differential Effects ◽  
Recent Onset ◽  
Onset Type

2436-PUB: Predicting Risk for New-Onset Type 2 Diabetes in Chinese People with Coronary Heart Disease and Impaired Glucose Tolerance

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 2436-PUB
Author(s):  
SHISHI XU ◽  
CHARLES A. SCOTT ◽  
RUTH L. COLEMAN ◽  
JAAKKO TUOMILEHTO ◽  
RURY R. HOLMAN
Keyword(s):  
Type 2 Diabetes ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Glucose Tolerance ◽  
Impaired Glucose Tolerance ◽  
Chinese People ◽  
Onset Type ◽  
New Onset

834-P: Weight Change and Dementia Risk in Patients with New-Onset Type 2 Diabetes: A Nationwide Cohort Study

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 834-P
Author(s):  
HYUK-SANG KWON ◽  
SOON JIB YOO ◽  
MIN-KYUNG LEE ◽  
GA EUN NAM
Keyword(s):  
Type 2 Diabetes ◽  
Cohort Study ◽  
Weight Change ◽  
Onset Type ◽  
Dementia Risk ◽  
New Onset

522-P: Long-Term Renal Outcomes in Young Onset Type 2 Diabetes

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 522-P
Author(s):  
TIMOTHY MIDDLETON ◽  
STEVE CHADBAN ◽  
LYNDA M. MOLYNEAUX ◽  
MARIO I. D'SOUZA ◽  
MARIA I. CONSTANTINO ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Young Onset ◽  
Onset Type ◽  
Renal Outcomes

279-OR: Cognition in Young Adults with Youth-Onset Type 1 and Type 2 Diabetes: The SEARCH for Diabetes in Youth Study

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 279-OR
Author(s):  
ALLISON SHAPIRO ◽  
DANA DABELEA ◽  
JEANETTE M. STAFFORD ◽  
RALPH DAGOSTINO ◽  
CATHERINE PIHOKER ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Young Adults ◽  
Onset Type ◽  
Youth Study ◽  
Diabetes In Youth

542-P: Association of Cardiac Autonomic Dysfunction with Plasma Lipid Metabolites in Recent-Onset Type 2 Diabetes

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 542-P
Author(s):  
GIDON J. BÖNHOF ◽  
ALEXANDER STROM ◽  
KLAUS STRASSBURGER ◽  
BIRGIT KNEBEL ◽  
JORG KOTZKA ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Autonomic Dysfunction ◽  
Plasma Lipid ◽  
Recent Onset ◽  
Onset Type ◽  
Cardiac Autonomic Dysfunction ◽  
Lipid Metabolites
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