scholarly journals Reducing Inpatient Hypoglycemia in the General Wards Using Real-time Continuous Glucose Monitoring: The Glucose Telemetry System, a Randomized Clinical Trial

Diabetes Care ◽  
2020 ◽  
Vol 43 (11) ◽  
pp. 2736-2743 ◽  
Author(s):  
Lakshmi G. Singh ◽  
Medha Satyarengga ◽  
Isabel Marcano ◽  
William H. Scott ◽  
Lillian F. Pinault ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Real Time ◽  
Continuous Glucose Monitoring ◽  
Glucose Monitoring ◽  
Telemetry System ◽  
System A ◽  
General Wards

Reducing inpatient hypoglycemia in the general wards using real-time CGM- the Glucose Telemetry system: A randomized clinical trial

2020 ◽  
Author(s):  
Lakshmi G. Singh ◽  
Medha Satyarengga ◽  
Isabel Marcano ◽  
William H. Scott ◽  
Lillian F. Pinault ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Clinical Trial ◽  
High Risk ◽  
Randomized Clinical Trial ◽  
Real Time ◽  
Lower Percentage ◽  
Telemetry System ◽  
Glucose Testing ◽  
General Wards

OBJECTIVE: Use of real-time continuous glucose monitoring (RT-CGM) systems in the inpatient setting is considered investigational. The objective of this study was to evaluate whether RT-CGM, using the glucose telemetry system (GTS), can prevent hypoglycemia in the general wards. <p>RESEARCH DESIGN AND METHODS: In a randomized clinical trial, insulin-treated patients at high risk for hypoglycemia with type 2 diabetes were recruited. Participants were randomized to RT-CGM/GTS or point of care (POC) blood glucose testing. The primary outcome was difference in inpatient hypoglycemia.</p> <p>RESULTS: Seventy-two participants were included in this interim analysis, 36 in the RT-CGM/GTS group and 36 in the POC group. RT-CGM/GTS group experienced fewer hypoglycemic events (<70 mg/dL) per patient (0.67 events per patient, 95% CI 0.34-1.30 versus 1.69 events per patient, 95% CI 1.11-2.58, <i>p</i>=0.024) and fewer clinically significant hypoglycemic events (<54 mg/dL) per patient (0.08 events per patient, 95% CI 0.03-0.26 versus 0.75, 95% CI 0.51-1.09, <i>p</i>=0.003). RT-CGM/GTS had lower percentage of time spent below range <70 mg/dl (0.40%, 95% CI 0.18%-0.92% versus 1.88%, 95% CI 1.26%-2.81%, <i>p</i>=0.002) and <54 mg/dL (0.05%, 95% CI 0.01%-0.43% versus 0.82%, 95% CI 0.47%-1.43%, <i>p</i>=0.017) compared to POC group. No differences in nocturnal hypoglycemia, time in range 70-180 mg/dL, time above range >180-250 mg/dL and >250 mg/dL were found between the groups. RT-CGM/GTS group had no prolonged hypoglycemia compared to 0.20 episodes <54mg/dL and 0.40 episodes <70mg/dL per patient in the POC group. </p> <p>CONCLUSIONS: RT-CGM/GTS can decrease hypoglycemia among hospitalized high risk insulin treated patients with type 2 diabetes.</p>

scholarly journals Reducing inpatient hypoglycemia in the general wards using real-time CGM- the Glucose Telemetry system: A randomized clinical trial

2020 ◽  
Author(s):  
Lakshmi G. Singh ◽  
Medha Satyarengga ◽  
Isabel Marcano ◽  
William H. Scott ◽  
Lillian F. Pinault ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Clinical Trial ◽  
High Risk ◽  
Randomized Clinical Trial ◽  
Real Time ◽  
Lower Percentage ◽  
Telemetry System ◽  
Glucose Testing ◽  
General Wards

OBJECTIVE: Use of real-time continuous glucose monitoring (RT-CGM) systems in the inpatient setting is considered investigational. The objective of this study was to evaluate whether RT-CGM, using the glucose telemetry system (GTS), can prevent hypoglycemia in the general wards. <p>RESEARCH DESIGN AND METHODS: In a randomized clinical trial, insulin-treated patients at high risk for hypoglycemia with type 2 diabetes were recruited. Participants were randomized to RT-CGM/GTS or point of care (POC) blood glucose testing. The primary outcome was difference in inpatient hypoglycemia.</p> <p>RESULTS: Seventy-two participants were included in this interim analysis, 36 in the RT-CGM/GTS group and 36 in the POC group. RT-CGM/GTS group experienced fewer hypoglycemic events (<70 mg/dL) per patient (0.67 events per patient, 95% CI 0.34-1.30 versus 1.69 events per patient, 95% CI 1.11-2.58, <i>p</i>=0.024) and fewer clinically significant hypoglycemic events (<54 mg/dL) per patient (0.08 events per patient, 95% CI 0.03-0.26 versus 0.75, 95% CI 0.51-1.09, <i>p</i>=0.003). RT-CGM/GTS had lower percentage of time spent below range <70 mg/dl (0.40%, 95% CI 0.18%-0.92% versus 1.88%, 95% CI 1.26%-2.81%, <i>p</i>=0.002) and <54 mg/dL (0.05%, 95% CI 0.01%-0.43% versus 0.82%, 95% CI 0.47%-1.43%, <i>p</i>=0.017) compared to POC group. No differences in nocturnal hypoglycemia, time in range 70-180 mg/dL, time above range >180-250 mg/dL and >250 mg/dL were found between the groups. RT-CGM/GTS group had no prolonged hypoglycemia compared to 0.20 episodes <54mg/dL and 0.40 episodes <70mg/dL per patient in the POC group. </p> <p>CONCLUSIONS: RT-CGM/GTS can decrease hypoglycemia among hospitalized high risk insulin treated patients with type 2 diabetes.</p>

scholarly journals Continuous Glucose Monitoring in General Wards for Prevention of Hypoglycemia: Results From the Glucose Telemetry System Pilot Study

2019 ◽  
Vol 14 (4) ◽  
pp. 783-790 ◽  
Author(s):  
Lakshmi G. Singh ◽  
David L. Levitt ◽  
Medha Satyarengga ◽  
Lillian Pinault ◽  
Min Zhan ◽  
...  
Keyword(s):  
Pilot Study ◽  
Continuous Glucose Monitoring ◽  
Glucose Monitoring ◽  
Telemetry System ◽  
General Wards

Effect of a Novel High Fiber Rice Diet on 24-Hour Glycemic Responses in Asian Indians Using Continuous Glucose Monitoring: A Randomized Clinical Trial

2019 ◽  
Vol 21 (4) ◽  
pp. 177-182 ◽  
Author(s):  
Ranjit Mohan Anjana ◽  
Rajagopal Gayathri ◽  
Nagarajan Lakshmipriya ◽  
Mookambika Ramya Bai ◽  
Shobana Shanmugam ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Continuous Glucose Monitoring ◽  
Asian Indians ◽  
Glucose Monitoring ◽  
High Fiber ◽  
Rice Diet
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