scholarly journals The Association of Energy and Macronutrient Intake at Dinner Versus Breakfast With Disease-Specific and All-Cause Mortality Among People With Diabetes: The U.S. National Health and Nutrition Examination Survey, 2003–2014

Diabetes Care ◽  
2020 ◽  
Vol 43 (7) ◽  
pp. 1442-1448 ◽  
Author(s):  
Tianshu Han ◽  
Jian Gao ◽  
Lihong Wang ◽  
Chao Li ◽  
Lu Qi ◽  
...  
2020 ◽  
Author(s):  
Tianshu Han ◽  
Jian Gao ◽  
Lihong Wang ◽  
Chao Li ◽  
Lu Qi ◽  
...  

<b>Objective </b>This study aims<b> </b>to evaluate the association of energy and macronutrients intake at dinner vs. breakfast with disease-specific and all-cause mortality in people with diabetes. <div><p><b>Methods </b>4699 peoples with diabetes who enrolled in the National Health and Nutrition Examination Survey from 2003 to 2014 were recruited for this study. Energy and macronutrients intake were measured by a 24h dietary-recall. The Differences(△) in energy and macronutrients intake between dinner and breakfast (△=dinner minus breakfast) were categorized into quintiles. Death information was obtained from the National Death Index until 2015. Cox proportional hazards regression models were developed to evaluate the survival relationship between △ and diabetes, cardiovascular-disease (CVD) and all-cause mortality. </p> <p><b>Results</b> Of the 4699 participants, 913 deaths, including 269 deaths due to diabetes and 314 deaths due to CVD, were documented. After adjusting for potential confounders, compared with participants in the lowest quintile of Δ in terms of total energy and protein, participants in the highest quintile were more likely to die due to diabetes (HR<sub>Δenergy</sub>=1.92, 99% CI:1.08-3.42; HR<sub>Δprotein</sub>=1.92, 99% CI:1.06-3.49) and CVD (HR<sub>Δenergy</sub>=1.69, 99% CI:1.02-2.80; HR<sub>Δprotein</sub>=1.96, 99% CI:1.14-3.39). The highest quintile of Δ from total-fat was related with CVD mortality (HR=1.67, 99% CI: 1.01-2.76). Isocalorically replacing 5% of total-energy at dinner with breakfast was associated with 4% and 5% lower risk of diabetes (HR=0.96, 95% CI: 0.94-0.98) and CVD (HR=0.95, 95% CI: 0.93-0.97) mortality.</p> <p><b>Conclusions</b> Higher intake of energy, total-fat and protein from dinner than breakfast was associated with greater diabetes, CVD and all-cause mortality in people with diabetes. <b></b></p><b></b></div>


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Akinkunle Oye-Somefun ◽  
Jennifer L. Kuk ◽  
Chris I. Ardern

Abstract Background We examined the relationship between ratios of select biomarkers of kidney and liver function on all-cause and coronary heart disease (CHD) mortality, both in isolation, and in combination with metabolic syndrome (MetS), among adults (20 + years, n = 10,604). Methods Data was derived from the U.S. National Health and Nutrition Examination Survey (1999–2016) including public-use linked mortality follow-up files through December 31, 2015. Results Select biomarker ratios of kidney (UACR or albuminuria and BUN-CR) and liver (AST-ALT and GGT-ALP) function in isolation and in combination with MetS were associated with all-cause and CHD mortality. Compared to individuals with neither elevated biomarker ratios nor MetS (HR = 1.00, referent), increased risk of all-cause mortality was observed in the following groups: MetS with elevated UACR (HR, 95% CI = 2.57, 1.99–3.33), MetS with elevated AST-ALT (HR = 2.22, 1.61–3.07), elevated UACR without MetS (HR = 2.12, 1.65–2.72), and elevated AST-ALT without MetS (HR = 1.71, 1.35–2.18); no other biomarker ratios were associated with all-cause mortality. For cause-specific deaths, elevated risk of CHD mortality was associated with MetS with elevated UACR (HR = 1.67, 1.05–2.67), MetS with elevated AST-ALT (HR = 2.80, 1.62–4.86), and elevated BUN-CR without MetS (HR = 2.12, 1.12–4.04); no other biomarker ratios were associated with CHD mortality. Conclusion Future longitudinal studies are necessary to examine the utility of these biomarker ratios in risk stratification for chronic disease management.


2020 ◽  
Author(s):  
Tianshu Han ◽  
Jian Gao ◽  
Lihong Wang ◽  
Chao Li ◽  
Lu Qi ◽  
...  

<b>Objective </b>This study aims<b> </b>to evaluate the association of energy and macronutrients intake at dinner vs. breakfast with disease-specific and all-cause mortality in people with diabetes. <div><p><b>Methods </b>4699 peoples with diabetes who enrolled in the National Health and Nutrition Examination Survey from 2003 to 2014 were recruited for this study. Energy and macronutrients intake were measured by a 24h dietary-recall. The Differences(△) in energy and macronutrients intake between dinner and breakfast (△=dinner minus breakfast) were categorized into quintiles. Death information was obtained from the National Death Index until 2015. Cox proportional hazards regression models were developed to evaluate the survival relationship between △ and diabetes, cardiovascular-disease (CVD) and all-cause mortality. </p> <p><b>Results</b> Of the 4699 participants, 913 deaths, including 269 deaths due to diabetes and 314 deaths due to CVD, were documented. After adjusting for potential confounders, compared with participants in the lowest quintile of Δ in terms of total energy and protein, participants in the highest quintile were more likely to die due to diabetes (HR<sub>Δenergy</sub>=1.92, 99% CI:1.08-3.42; HR<sub>Δprotein</sub>=1.92, 99% CI:1.06-3.49) and CVD (HR<sub>Δenergy</sub>=1.69, 99% CI:1.02-2.80; HR<sub>Δprotein</sub>=1.96, 99% CI:1.14-3.39). The highest quintile of Δ from total-fat was related with CVD mortality (HR=1.67, 99% CI: 1.01-2.76). Isocalorically replacing 5% of total-energy at dinner with breakfast was associated with 4% and 5% lower risk of diabetes (HR=0.96, 95% CI: 0.94-0.98) and CVD (HR=0.95, 95% CI: 0.93-0.97) mortality.</p> <p><b>Conclusions</b> Higher intake of energy, total-fat and protein from dinner than breakfast was associated with greater diabetes, CVD and all-cause mortality in people with diabetes. <b></b></p><b></b></div>


2020 ◽  
Author(s):  
Tianshu Han ◽  
Jian Gao ◽  
Lihong Wang ◽  
Chao Li ◽  
Lu Qi ◽  
...  

<b>Objective </b>This study aims<b> </b>to evaluate the association of energy and macronutrients intake at dinner vs. breakfast with disease-specific and all-cause mortality in people with diabetes. <div><p><b>Methods </b>4699 peoples with diabetes who enrolled in the National Health and Nutrition Examination Survey from 2003 to 2014 were recruited for this study. Energy and macronutrients intake were measured by a 24h dietary-recall. The Differences(△) in energy and macronutrients intake between dinner and breakfast (△=dinner minus breakfast) were categorized into quintiles. Death information was obtained from the National Death Index until 2015. Cox proportional hazards regression models were developed to evaluate the survival relationship between △ and diabetes, cardiovascular-disease (CVD) and all-cause mortality. </p> <p><b>Results</b> Of the 4699 participants, 913 deaths, including 269 deaths due to diabetes and 314 deaths due to CVD, were documented. After adjusting for potential confounders, compared with participants in the lowest quintile of Δ in terms of total energy and protein, participants in the highest quintile were more likely to die due to diabetes (HR<sub>Δenergy</sub>=1.92, 99% CI:1.08-3.42; HR<sub>Δprotein</sub>=1.92, 99% CI:1.06-3.49) and CVD (HR<sub>Δenergy</sub>=1.69, 99% CI:1.02-2.80; HR<sub>Δprotein</sub>=1.96, 99% CI:1.14-3.39). The highest quintile of Δ from total-fat was related with CVD mortality (HR=1.67, 99% CI: 1.01-2.76). Isocalorically replacing 5% of total-energy at dinner with breakfast was associated with 4% and 5% lower risk of diabetes (HR=0.96, 95% CI: 0.94-0.98) and CVD (HR=0.95, 95% CI: 0.93-0.97) mortality.</p> <p><b>Conclusions</b> Higher intake of energy, total-fat and protein from dinner than breakfast was associated with greater diabetes, CVD and all-cause mortality in people with diabetes. <b></b></p><b></b></div>


2021 ◽  
pp. 1-24
Author(s):  
Bushra Hoque ◽  
Zumin Shi

Abstract Selenium (Se) is a trace mineral that has antioxidant and anti-inflammatory properties. This study aimed to investigate the association between Se intake, diabetes, all-cause and cause-specific mortality in a representative sample of US adults. Data from 18,932 adults who attended the 2003-2014 National Health and Nutrition Examination Survey (NHANES) were analysed. Information on mortality was obtained from the US mortality registry updated to 2015. Multivariable logistic regression and Cox regression were used. Cross-sectionally, Se intake was positively associated with diabetes. Comparing extreme quartiles of Se intake, the odds ratio (OR) for diabetes was 1.44 (95% CI: 1.09–1.89). During a mean of 6.6 years follow-up, there were 1627 death (312 CVD, 386 cancer). High intake of Se was associated with a lower risk of all-cause mortality. When comparing the highest with the lowest quartiles of Se intake, the hazard ratios (HRs) for all-cause, CVD mortality, cancer mortality and other mortality were: 0.77 (95% CI 0.59-1.01), 0.62 (95% CI, 0.35-1.13), 1.42 (95% CI, 0.78-2.58) and 0.60 (95% CI,0.40-0.80), respectively. The inverse association between Se intake and all-cause mortality was only found among white participants. In conclusion, Se intake was positively associated with diabetes but inversely associated with all-cause mortality. There was no interaction between Se intake and diabetes in relation to all-cause mortality.


Diabetes Care ◽  
2002 ◽  
Vol 25 (8) ◽  
pp. 1326-1330 ◽  
Author(s):  
J. B. Saaddine ◽  
A. Fagot-Campagna ◽  
D. Rolka ◽  
K.M. V. Narayan ◽  
L. Geiss ◽  
...  

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