scholarly journals Amount and Type of Dietary Fat, Postprandial Glycemia, and Insulin Requirements in Type 1 Diabetes: A Randomized Within-Subject Trial

Diabetes Care ◽  
2019 ◽  
Vol 43 (1) ◽  
pp. 59-66 ◽  
Author(s):  
Kirstine J. Bell ◽  
Chantelle Z. Fio ◽  
Stephen Twigg ◽  
Sally-Anne Duke ◽  
Gregory Fulcher ◽  
...  
Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 290-OR
Author(s):  
KIRSTINE BELL ◽  
SALLY DUKE ◽  
KYLIE M. ALEXANDER ◽  
MARGARET MCGILL ◽  
JENCIA WONG ◽  
...  

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 795-P
Author(s):  
DALIA DALLE ◽  
SARINE G. SHAHMIRIAN ◽  
MARYANN O'RIORDAN ◽  
TERESA N. ZIMMERMAN ◽  
JAMIE R. WOOD

2021 ◽  
Author(s):  
Susan M. O'Connell ◽  
Norma M. A. O'Toole ◽  
Conor N. Cronin ◽  
Chen Saat‐Murphy ◽  
Patrick McElduff ◽  
...  

Diabetologia ◽  
2009 ◽  
Vol 53 (3) ◽  
pp. 446-451 ◽  
Author(s):  
A. García-Patterson ◽  
I. Gich ◽  
S. B. Amini ◽  
P. M. Catalano ◽  
A. de Leiva ◽  
...  

2014 ◽  
Vol 7 (2) ◽  
pp. 52-59 ◽  
Author(s):  
Naomi Achong ◽  
Harold David McIntyre ◽  
Leonie Callaway

Most women with type 1 diabetes mellitus (T1DM) have increased insulin requirements during pregnancy. However, a minority of women have a fall in insulin requirements. When this occurs in late gestation, it often provokes concern regarding possible compromise of the feto-placental unit. In some centres, this is considered as an indication for delivery, including premature delivery. There are, however, many other factors that affect insulin requirements in pregnancy in women with type 1 diabetes mellitus and the decline in insulin requirements may represent a variant of normal pregnancy. If there is no underlying pathological process, expedited delivery in these women is not warranted and confers increased risks to the newborn. We will explore the factors affecting insulin requirements in gestation in this review. We will also discuss some novel concepts regarding beta-cell function in pregnancy.


2016 ◽  
Vol 11 (4) ◽  
pp. 753-758 ◽  
Author(s):  
Asma Deeb ◽  
Ahlam Al Hajeri ◽  
Iman Alhmoudi ◽  
Nico Nagelkerke

Background: Carbohydrate (CHO) counting is a key nutritional intervention utilized in the management of diabetes to optimize postprandial glycemia. The aim of the study was to examine the impact of accuracy of CHO counting on the postprandial glucose in children and adolescents with type 1 diabetes on insulin pump therapy. Methods: Children/adolescents with type 1 diabetes who were on insulin pump therapy for a minimum of 6 months are enrolled in the study. Patients were instructed to record details of meals consumed, estimated CHO count per meal, and 2-hour postprandial glucose readings over 3-5 days. Meals’ CHO contents were recounted by an experienced clinical dietician, and those within 20% of the dietician’s counting were considered accurate. Results: A total of 30 patients (21 females) were enrolled. Age range (median) was 8-18 (SD 13) years. Data of 247 meals were analyzed. A total of 165 (67%) meals’ CHO contents were accurately counted. Of those, 90 meals (55%) had in-target postprandial glucose ( P < .000). There was an inverse relationship between inaccurate CHO estimates and postprandial glucose. Of the 63 underestimated meals, 55 had above-target glucose, while 12 of the 19 overestimated meals were followed by low glucose. There was no association between accuracy and meal size (Spearman’s rho = .019). Conclusion: Accuracy of CHO counting is an important determining factor of postprandial glycemia. However, other factors should be considered when advising on prandial insulin calculation. Underestimation and overestimation of CHO result in postprandial hyperglycemia and hypoglycemia, respectively. Accuracy does not correlate with meal size.


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