scholarly journals High-Dose Folic Acid Supplement Use From Prepregnancy Through Midpregnancy Is Associated With Increased Risk of Gestational Diabetes Mellitus: A Prospective Cohort Study

Diabetes Care ◽  
2019 ◽  
Vol 42 (7) ◽  
pp. e113-e115 ◽  
Author(s):  
Qian Li ◽  
Yu Zhang ◽  
Li Huang ◽  
Chunrong Zhong ◽  
Renjuan Chen ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Cohort Study ◽  
Folic Acid ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Prospective Cohort ◽  
High Dose ◽  
Folic Acid Supplement ◽  
Supplement Use ◽  
Increased Risk

scholarly journals Maternal dietary patterns and gestational diabetes mellitus: a large prospective cohort study in China

2015 ◽  
Vol 113 (8) ◽  
pp. 1292-1300 ◽  
Author(s):  
Jian-Rong He ◽  
Ming-Yang Yuan ◽  
Nian-Nian Chen ◽  
Jin-Hua Lu ◽  
Cui-Yue Hu ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Cohort Study ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Prospective Cohort Study ◽  
Dietary Patterns ◽  
Prospective Cohort ◽  
Family History Of Diabetes ◽  
Increased Risk ◽  
Protein Rich

Few studies have explored the relationship between dietary patterns and the risk of gestational diabetes mellitus (GDM). Evidence from non-Western areas is particularly lacking. In the present study, we aimed to examine the associations between dietary patterns and the risk of GDM in a Chinese population. A total of 3063 pregnant Chinese women from an ongoing prospective cohort study were included. Data on dietary intake were collected using a FFQ at 24–27 weeks of gestation. GDM was diagnosed using a 75 g, 2 h oral glucose tolerance test. Dietary patterns were determined by principal components factor analysis. A log-binomial regression model was used to examine the associations between dietary pattern and the risk of GDM. The analysis identified four dietary patterns: vegetable pattern; protein-rich pattern; prudent pattern; sweets and seafood pattern. Multivariate analysis showed that the highest tertile of the vegetable pattern was associated with a decreased risk of GDM (relative risk (RR) 0·79, 95 % CI 0·64, 0·97), compared with the lowest tertile, whereas the highest tertile of the sweets and seafood pattern was associated with an increased risk of GDM (RR 1·23, 95 % CI 1·02, 1·49). No significant association was found for either the protein-rich or the prudent pattern. The protective effect of a high vegetable pattern score was more evident among women who had a family history of diabetes (P for interaction = 0·022). These findings suggest that the vegetable pattern was associated with a decreased risk of GDM, while the sweets and seafood pattern was associated with an increased risk of GDM. These findings may be useful in dietary counselling during pregnancy.

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