scholarly journals Role and Determinants of Adherence to Off-loading in Diabetic Foot Ulcer Healing: A Prospective Investigation

Diabetes Care ◽  
2016 ◽  
Vol 39 (8) ◽  
pp. 1371-1377 ◽  
Author(s):  
Ryan T. Crews ◽  
Biing-Jiun Shen ◽  
Laura Campbell ◽  
Peter J. Lamont ◽  
Andrew J.M. Boulton ◽  
...  
Keyword(s):  
Ulcer Healing ◽  
Diabetic Foot ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Prospective Investigation

scholarly journals Response to Comment on Crews et al. Role and Determinants of Adherence to Off-loading in Diabetic Foot Ulcer Healing: A Prospective Investigation. Diabetes Care 2016;39:1371–1377

Diabetes Care ◽  
2016 ◽  
Vol 39 (12) ◽  
pp. e222-e223 ◽  
Author(s):  
Ryan T. Crews ◽  
Biing-Jiun Shen ◽  
Laura Campbell ◽  
Peter J. Lamont ◽  
Matthew Hardman ◽  
...  
Keyword(s):  
Ulcer Healing ◽  
Diabetes Care ◽  
Diabetic Foot ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Prospective Investigation

Intermittent cycles of remote ischemic preconditioning augment diabetic foot ulcer healing

2015 ◽  
Vol 23 (2) ◽  
pp. 191-196 ◽  
Author(s):  
Gad Shaked ◽  
David Czeiger ◽  
Anwar Abu Arar ◽  
Tiberiu Katz ◽  
Ilana Harman-Boehm ◽  
...  
Keyword(s):  
Ischemic Preconditioning ◽  
Ulcer Healing ◽  
Diabetic Foot ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Remote Ischemic Preconditioning

scholarly journals Health literacy and diabetic foot ulcer healing

2015 ◽  
Vol 23 (3) ◽  
pp. 299-301 ◽  
Author(s):  
David J. Margolis ◽  
Michelle Hampton ◽  
Ole Hoffstad ◽  
D. Scot Malay ◽  
Stephen Thom
Keyword(s):  
Health Literacy ◽  
Ulcer Healing ◽  
Diabetic Foot ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer

scholarly journals A Pilot Randomized, Controlled Study of Nanocrystalline Silver, Manuka Honey, and Conventional Dressing in Healing Diabetic Foot Ulcer

2017 ◽  
Vol 2017 ◽  
pp. 1-15 ◽  
Author(s):  
Ka-Kit Tsang ◽  
Enid Wai-Yung Kwong ◽  
Tony Shing-Shun To ◽  
Joanne Wai-Yee Chung ◽  
Thomas Kwok-Shing Wong
Keyword(s):  
Ulcer Healing ◽  
Diabetic Foot ◽  
Reduction Rate ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Size Reduction ◽  
Controlled Study ◽  
Manuka Honey ◽  
Ulcer Size ◽  
Randomized Controlled

Nanocrystalline silver (nAg) and Manuka honey (MH) dressing have increasing popularity for treating diabetic foot ulcer (DFU). This study was an open-label randomized controlled trial with three parallel groups’ design in examining the preliminary effectiveness of nAg against MH and conventional dressing in healing DFU in terms of ulcer healing, ulcer infection, and inflammation. 31 participants (11 in the nAg group, 10 in the MH group, and 10 in the convention group) diagnosed with type 2 diabetes were enrolled. Wound cleaning, debridement, and topical dressing application were performed according to the group allocation in each visit at weeks 1, 2, 3, 4, 6, 8, 10, and 12. The results found that the proportions of complete ulcer healing were 81.8%, 50%, and 40% in the nAg, MH, and conventional groups, respectively. The ulcer size reduction rate was potentially higher in the nAg group (97.45%) than the MH group (86.21%) and the conventional group (75.17%). In bacteriology, nAg showed a greater rate of microorganism reduction although it was not significant. To conclude, nAg alginate was potentially superior to MH and conventional dressing in healing diabetic foot ulcer in terms of ulcer size reduction rate.

Continuous diffusion of oxygen improves diabetic foot ulcer healing when compared with a placebo control: a randomised, double-blind, multicentre study

2018 ◽  
Vol 27 (Sup9) ◽  
pp. S30-S45 ◽  
Author(s):  
Mark Q. Niederauer ◽  
Joel E. Michalek ◽  
Qianqian Liu ◽  
Klearchos K. Papas ◽  
Lawrence A. Lavery ◽  
...  
Keyword(s):  
Multicentre Study ◽  
Ulcer Healing ◽  
Diabetic Foot ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Placebo Control ◽  
Double Blind

scholarly journals Efficacy of Cellular Therapy for Diabetic Foot Ulcer

2017 ◽  
Vol 26 (12) ◽  
pp. 1931-1939 ◽  
Author(s):  
Ye Zhang ◽  
Hong Deng ◽  
Zhouping Tang
Keyword(s):  
Ulcer Healing ◽  
Diabetic Foot ◽  
Cellular Therapy ◽  
Meta Analysis ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Mean Difference ◽  
Cochrane Library ◽  
Transcutaneous Oxygen ◽  
Randomized Controlled

Diabetes mellitus is a widely spread chronic disease with growing incidence worldwide, and diabetic foot ulcer is one of the most serious complications of diabetes. Cellular therapy has shown promise in the management of diabetic foot ulcer in many preclinical experiments and clinical researches. Here, we performed a meta-analysis to evaluate the efficacy and safety of cellular therapy in the management of diabetic foot ulcer. We systematically searched PubMed, MEDLINE, EMBASE, and Cochrane Library databases from inception to May 2017 for randomized controlled trials assessing the efficacy of cellular therapy in diabetic foot ulcer, and a meta-analysis was conducted. A total of 6 randomized controlled clinical trials involving 241 individuals were included in this meta-analysis. The results suggested that cellular therapy could help accelerating the healing of diabetic foot ulcer, presented as higher ankle-brachial index (mean difference = 0.17, 95% confidence interval [CI] = 0.11 to 0.23), higher transcutaneous oxygen pressure (standardized mean difference [SMD] = 1.43; 95% CI, 1.09– to 1.78), higher ulcer healing rate (relative risk [RR] = 1.78; 95% CI, 1.41 to 2.25), higher amputation-free survival (RR = 1.25; 95% CI, 1.11 to 1.40), and lower scale of pain (SMD = −1.69; 95% CI, −2.05 to −1.33). Furthermore, cellular therapy seemed to be safe, with no serious complications and low risk of short-term slight complications. Cellular therapy could accelerate the rate of diabetic foot ulcer healing and may be more efficient than standard therapy for diabetic foot treatment.

scholarly journals Biofilm and diabetic foot ulcer healing: all hat and no cattle

2019 ◽  
Vol 7 (7) ◽  
pp. 159-159 ◽  
Author(s):  
Lawrence A. Lavery ◽  
Kavitha Bhavan ◽  
Dane K. Wukich
Keyword(s):  
Ulcer Healing ◽  
Diabetic Foot ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer
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