scholarly journals Latent Autoimmune Diabetes in Adults Presenting as Diabetes "Recurrence" After Bariatric Surgery: A Case Report

Diabetes Care ◽  
2013 ◽  
Vol 36 (8) ◽  
pp. e120-e120 ◽  
Author(s):  
S. B. Manning ◽  
A. Pucci ◽  
R. L. Batterham ◽  
N. Finer
Author(s):  
Cristen P. Page ◽  
Brian Fitzgerald ◽  
Emily M. Hawes

2001 ◽  
Vol 119 (2) ◽  
pp. 84-85 ◽  
Author(s):  
João Paulo Botelho Vieira Filho ◽  
Regina Célia Santiago Moisés ◽  
João Roberto de Sá ◽  
Antonio Roberto Chacra ◽  
Sergio Atala Dib

CONTEXT: Latent autoimmune diabetes of the adult (LADA) as originally described represents perhaps as many as 10 -- 20% of adult-onset patients with diabetes. DESIGN: case report. CASE REPORT: A 38-year-old Brazilian Xavante-Jê Indian with Latent Autoimmune Diabetes of the Adult (LADA) is described, coming from the Sangradouro community in Poxoréu, Mato Grosso. The onset of diabetes after reaching 25 years of age, the evolution to insulin deficiency after a period of insulin-independence and the presence of auto-antibodies to glutamic acid decarboxylase (GAD) characteristic of LADA were present. This patient may represent the first case of LADA in a Brazilian with full Indian heritage. Further studies are necessary to verify the prevalence of this new type of diabetes in this population that does not have Caucasoid admixture and has a particular environmental background.


2010 ◽  
Vol 17 (3) ◽  
pp. 284-287 ◽  
Author(s):  
Valmore Bermúdez ◽  
Daniel Aparicio ◽  
Carlos Colmenares ◽  
Lianny Peñaranda ◽  
Yettana Luti ◽  
...  

Obesity Facts ◽  
2021 ◽  
pp. 1-6
Author(s):  
Marta Guimarães ◽  
Sofia S. Pereira ◽  
Mário Nora ◽  
Mariana P. Monteiro

Bariatric surgery is a very effective treatment for obesity-associated type 2 diabetes. However, the benefits of bariatric surgery in patients with obesity and autoimmune diabetes, such as type 1 diabetes and latent autoimmune diabetes in adults (LADA), are controversial. We report 3 female patients with obesity and LADA who underwent laparoscopic Roux-en-Y gastric bypass &#x3e;10 years ago. The patients were diagnosed with LADA both 1 and 9 years before (<i>n</i> = 2) or 11 years after the surgery (<i>n</i> = 1). Patients preoperative body mass index ranged from 36 to 47 kg/m<sup>2</sup> and improved to 23–37 kg/m<sup>2</sup> in the last follow-up visit, 10–15 years after surgery. Daily insulin dose also decreased from an average of 0.68 to 0.45 IU/kg in those patients treated with insulin before bariatric surgery. Only one patient developed diabetes-related target organ damage. This study shows that patients with LADA depict remarkable reduction of body weight and insulin requirements over long-term after bariatric surgery. So, LADA should not be considered a contraindication for bariatric surgery yet should only be recommended for patients with concomitant obesity with the primary aim of achieving sustained weight loss.


2019 ◽  
Vol 7 (20) ◽  
pp. 3501-3504
Author(s):  
Afdol Rahmadi ◽  
Eva Decroli ◽  
Alexander Kam

BACKGROUND: This case report intends to highlight the challenge in diagnosing type 1 diabetes on an adult patient. Latent Autoimmune Diabetes in Adult (LADA) types I diabetes Mellitus, which found in adulthood and characterised by progressive damage to pancreatic β cells that happened slowly. Incidence of LADA is around 2-12% of the total diabetes population. Sepsis in LADA patients will trigger diabetic ketoacidosis (DKA). CASE REPORT: We report a case of a 33-year-old woman patient presents with decreased consciousness accompanied by rapid and deep breathlessness for 1 day. Before, the patient complains of fever and cough. Physical examination found soporous, blood pressure 120/80 mmHg, pulse 110 x/minute, temperature 38.8°C, breathing 32 x/minute Kussmaul. Bronchovesicular breath crackles in both lower lung fields. leukocytes were 22,100/mm3, random blood glucose 638 mg/dL, urine ketone +++, HbA1C 17.2%, HOMA IR less than 2 units. C-peptide 0.3 ng/mL and GADAs 16.9 U/mL. Chest Xray indicated bronchopneumonia. Patients were diagnosed with diabetic ketoacidosis, LADA, and sepsis caused by bronchopneumonia. Patient treated with DKA management and sepsis. On the second day, the treatment of DKA was resolved and continued with the administration of short-acting insulin and regular long-acting. CONCLUSION: Sepsis in LADA with DKA requires fast and appropriate management. Further search is needed to diagnose LADA.


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