scholarly journals Lack of Effectiveness of Hyperbaric Oxygen Therapy for the Treatment of Diabetic Foot Ulcer and the Prevention of Amputation: A cohort study

Diabetes Care ◽  
2013 ◽  
Vol 36 (7) ◽  
pp. 1961-1966 ◽  
Author(s):  
D. J. Margolis ◽  
J. Gupta ◽  
O. Hoffstad ◽  
M. Papdopoulos ◽  
H. A. Glick ◽  
...  
Keyword(s):  
Cohort Study ◽  
Hyperbaric Oxygen ◽  
Diabetic Foot ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer

scholarly journals Effects of adding adjunctive hyperbaric oxygen therapy to standard wound care for diabetic foot ulcers: a protocol for a systematic review with meta-analysis and trial sequential analysis

BMJ Open ◽  
2020 ◽  
Vol 10 (6) ◽  
pp. e031708 ◽  
Author(s):  
Julie Vinkel ◽  
Niels Frederich Rose Holm ◽  
Janus C Jakobsen ◽  
Ole Hyldegaard
Keyword(s):  
Hyperbaric Oxygen ◽  
Diabetic Foot ◽  
Hyperbaric Oxygen Therapy ◽  
Sequential Analysis ◽  
Oxygen Therapy ◽  
Wound Care ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Risk Of Bias ◽  
Trial Sequential Analysis

IntroductionDiabetic foot ulcer represents a major health problem globally. Preliminary studies have indicated that systemic treatment of diabetic foot ulcer patients with hyperbaric oxygen therapy have beneficial effects on wound healing, risk of amputation, glycaemic control, atherosclerosis, inflammatory markers and other clinical and laboratory parameters. This protocol for a systematic review aims at identifying the beneficial and harmful effects of adding hyperbaric oxygen therapy to standard wound care for diabetic foot ulcers.Methods and analysisThis protocol was performed following the recommendations of the Cochrane Collaboration and the eight-step assessment procedure suggested by Jakobsen and colleagues. We plan to include all relevant randomised clinical trials assessing the effects of hyperbaric oxygen therapy in the treatment of diabetic foot ulcer versus any control group with any intervention defined as standard wound care or similar, together with sham interventions. Our primary outcome will be: all-cause mortality, serious adverse events and quality of life. Our secondary outcomes will be: healing of index wound, major amputation and wound infection. Any eligible trial will be assessed and classified as either high risk of bias or low risk of bias, and our conclusions will be based on trials with low risk of bias. The analyses of the extracted data will be performed using Review Manager 5 and Trial Sequential Analysis. For both our primary and secondary outcomes, we will create a ‘Summary of Findings’ table and use GRADE (Grading of Recommendations Assessment, Development and Evaluation) assessment to assess the quality of the evidence.Ethics and disseminationWe use publicly accessible documents as evidence, there is no participant involvement at an individual level and an institutional ethics approval is not required. The results of the review will be sought published in a peer-reviewed journals, also in the event of insignificant results or null results, and thereby it will be disseminated to clinicians and public available.PROSPERO registration numberCRD42019139256.

Adjunctive Systemic Hyperbaric Oxygen Therapy in Treatment of Severe Prevalently Ischemic Diabetic Foot Ulcer: A randomized study

Diabetes Care ◽  
1996 ◽  
Vol 19 (12) ◽  
pp. 1338-1343 ◽  
Author(s):  
E. Faglia ◽  
F. Favales ◽  
A. Aldeghi ◽  
P. Calia ◽  
A. Quarantiello ◽  
...  
Keyword(s):  
Hyperbaric Oxygen ◽  
Diabetic Foot ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Randomized Study ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer

scholarly journals Hyperbaric oxygen therapy in diabetic foot ulcer management – what’s new?

Rany ◽  
2020 ◽  
Vol 2020 (1) ◽  
pp. 7-16
Author(s):  
Jakub Włodarczyk ◽  
Paweł Karakuła ◽  
Joel Mathews ◽  
Marcin Włodarczyk
Keyword(s):  
Hyperbaric Oxygen ◽  
Diabetic Foot ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer
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