scholarly journals Influence of Diabetes on Left Ventricular Systolic and Diastolic Function and on Long-Term Outcome After Cardiac Resynchronization Therapy

Diabetes Care ◽  
2012 ◽  
Vol 36 (4) ◽  
pp. 985-991 ◽  
Author(s):  
U. Hoke ◽  
J. Thijssen ◽  
R. J. van Bommel ◽  
L. van Erven ◽  
E. T. van der Velde ◽  
...  
Keyword(s):  
Cardiac Resynchronization Therapy ◽  
Diastolic Function ◽  
Left Ventricular ◽  
Cardiac Resynchronization ◽  
Resynchronization Therapy ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Systolic And Diastolic Function

scholarly journals Lateral left ventricular lead position is superior to posterior position in long-term outcome of patients underwent cardiac resynchronization therapy

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
A Behon ◽  
W.R Schwertner ◽  
E.D Merkel ◽  
A Kovacs ◽  
B.K Lakatos ◽  
...  
Keyword(s):  
Cardiac Resynchronization Therapy ◽  
Left Ventricular ◽  
Cardiac Resynchronization ◽  
Resynchronization Therapy ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Lead Position ◽  
Ventricular Lead ◽  
All Cause Mortality

Abstract Background Preferring side branch of coronary sinus during cardiac resynchronization therapy (CRT) implantation is empirical due to the limited data on the association of left ventricular (LV) lead position and long-term clinical outcome. Purpose We evaluated the long-term all-cause mortality by LV lead non-apical positions and further characterized them by interlead electrical delay (IED). Methods In our retrospective database 2087 patients were registered between 2000 and 2018. Those with non-apical LV lead locations were classified into anterior (n=108), posterior (n=643), and lateral (n=1336) groups. All-cause mortality was assessed by Kaplan-Meier and Cox analyses. Echocardiographic response was measured 6 months after CRT implantation. Results During the median follow-up time of 3.7 years, 1150 (55.1%) patients died, 710 (53.1%) with lateral, 78 (72.2%) with anterior and 362 (56.3%) with posterior positions. Patients with lateral position had significantly better outcome in all-cause mortality compared to others (HR 0.80; 95% CI: 0.71–0.90; p<0.0001), which was also confirmed by multivariate analysis after adjusting for relevant clinical covariates (HR 0.81; 95% CI: 0.72–0.91; p<0.0001). When echocardiographic response was evaluated in the lateral group, patients with an IED longer than 110 ms (ROC AUC 0.63; 95% CI: 0.53–0.73; p=0.012) showed 2.1 times higher odds of improvement in echocardiographic response 6 months after the implantation. Conclusions In this study we proved that after CRT implantation only the lateral LV lead location was associated with long-term mortality benefit. Moreover, patients with this position showed the greatest echocardiographic response over 110 ms IED. Survival of total patient cohort Funding Acknowledgement Type of funding source: None

Assessment of coronary flow reserve predicts long-term outcome of responders to cardiac resynchronization therapy

2018 ◽  
Vol 34 (5) ◽  
pp. 763-770
Author(s):  
Kunio Yufu ◽  
Hidekazu Kondo ◽  
Tetsuji Shinohara ◽  
Yumi Ishii ◽  
Seiichiro Yoshimura ◽  
...  
Keyword(s):  
Cardiac Resynchronization Therapy ◽  
Coronary Flow Reserve ◽  
Coronary Flow ◽  
Cardiac Resynchronization ◽  
Resynchronization Therapy ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Flow Reserve
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