scholarly journals Severe Hypoglycemia and Cardiovascular Disease Incidence in Type 1 Diabetes: The EURODIAB Prospective Complications Study

Diabetes Care ◽  
2012 ◽  
Vol 35 (7) ◽  
pp. 1598-1604 ◽  
Author(s):  
G. Gruden ◽  
F. Barutta ◽  
N. Chaturvedi ◽  
C. Schalkwijk ◽  
C. D. Stehouwer ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Type 1 Diabetes ◽  
Disease Incidence ◽  
Severe Hypoglycemia ◽  
Cardiovascular Disease Incidence

scholarly journals Risk stratification for 25-year cardiovascular disease incidence in type 1 diabetes: Tree-structured survival analysis of the Pittsburgh Epidemiology of Diabetes Complications study

2016 ◽  
Vol 13 (4) ◽  
pp. 250-259 ◽  
Author(s):  
Rachel G Miller ◽  
Stewart J Anderson ◽  
Tina Costacou ◽  
Akira Sekikawa ◽  
Trevor J Orchard
Keyword(s):  
Cardiovascular Disease ◽  
Type 1 Diabetes ◽  
Survival Analysis ◽  
Diabetes Complications ◽  
Disease Risk ◽  
Clinical Pathways ◽  
Disease Incidence ◽  
Cardiovascular Disease Risk ◽  
Diabetes Duration

Background: The formal identification of subgroups with varying levels of risk is uncommon in observational studies of cardiovascular disease, although such insight might be useful for clinical management. Methods: Tree-structured survival analysis was utilized to determine whether there are meaningful subgroups at varying levels of cardiovascular disease risk in the Pittsburgh Epidemiology of Diabetes Complications study, a prospective cohort study of childhood-onset (<17 years old) type 1 diabetes. Results: Of the 561 participants free of cardiovascular disease (coronary artery disease, stroke or lower extremity arterial disease) at baseline, 263 (46.9%) had an incident cardiovascular disease event over the 25-year follow-up. Tree-structured survival analysis revealed a range of risk groups, from 24% to 85%, which demonstrate that those with short diabetes duration and elevated non–high-density lipoprotein cholesterol have similar cardiovascular disease risk to those with long diabetes duration and that renal disease is a better discriminator of risk in men than in women. Conclusion: Our findings suggest that subgroups with major cardiovascular disease risk differences exist in this type 1 diabetes cohort. Using tree-structured survival analysis may help to identify these groups and the interrelationships between their associated risk factors. This approach may improve our understanding of various clinical pathways to cardiovascular disease and help target intervention strategies.

Short and long-term glycemic variability associated with severe hypoglycemia and retinopathy in type 1 diabetes mellitus

2020 ◽  
Author(s):  
Martín Borja Sanz ◽  
Gimeno Sergio Roman ◽  
Peteiro Miranda Carlos Miguel ◽  
Ortez Toro Jose Jorge ◽  
Ana Agudo ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Severe Hypoglycemia ◽  
Glycemic Variability ◽  
Short And Long Term

Risk Factors for Cardiovascular Disease (CVD) in Adults with Type 1 Diabetes (T1D)

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 15-LB
Author(s):  
SANJEEV N. MEHTA ◽  
MENGDI WU ◽  
NICOLE C. FOSTER ◽  
RODICA POP-BUSUI ◽  
MICHELLE KATZ ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Type 1 Diabetes

664-P: What Do Youth with Type 1 Diabetes (T1DM) and Caregivers Know about Cardiovascular Disease (CVD) Risk and Reduction?

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 664-P
Author(s):  
JODI KRALL ◽  
KRISTINE RUPPERT ◽  
ANA M. DIAZ ◽  
JESSICA FINNEY ◽  
LINDA M. SIMINERIO ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Type 1 Diabetes ◽  
Cvd Risk

269-OR: Effect of Insulin Degludec on Frequency of Severe Hypoglycemia in Patients with Type 1 Diabetes Prone to Nocturnal Severe Hypoglycemia: The HypoDeg Trial

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 269-OR
Author(s):  
RIKKE M. AGESEN ◽  
AMRA CIRIC ALIBEGOVIC ◽  
HENRIK U. ANDERSEN ◽  
PETER GUSTENHOFF ◽  
TROELS K. HANSEN ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Severe Hypoglycemia ◽  
Insulin Degludec
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