scholarly journals Visceral Fat Accumulation Is Associated With Circadian Blood Pressure in Japanese Patients With Impaired Glucose Tolerance

Diabetes Care ◽  
2011 ◽  
Vol 34 (3) ◽  
pp. e32-e32 ◽  
Author(s):  
T. Masaki ◽  
F. Anan ◽  
H. Yoshimatsu
Keyword(s):  
Blood Pressure ◽  
Glucose Tolerance ◽  
Impaired Glucose Tolerance ◽  
Visceral Fat ◽  
Japanese Patients ◽  
Fat Accumulation ◽  
Visceral Fat Accumulation ◽  
Circadian Blood Pressure

scholarly journals Experimental Weight Gain Increases Ambulatory Blood Pressure in Healthy Subjects: Implications of Visceral Fat Accumulation

2018 ◽  
Vol 93 (5) ◽  
pp. 618-626 ◽  
Author(s):  
Naima Covassin ◽  
Fatima H. Sert-Kuniyoshi ◽  
Prachi Singh ◽  
Abel Romero-Corral ◽  
Diane E. Davison ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Weight Gain ◽  
Ambulatory Blood Pressure ◽  
Visceral Fat ◽  
Healthy Subjects ◽  
Fat Accumulation ◽  
Visceral Fat Accumulation

scholarly journals Relationship among Systolic Blood Pressure, Serum Insulin and Leptin, and Visceral Fat Accumulation in Obese Children

2003 ◽  
Vol 26 (4) ◽  
pp. 281-288 ◽  
Author(s):  
Masahiro NISHINA ◽  
Toru KIKUCHI ◽  
Hisashi YAMAZAKI ◽  
Kazuhiro KAMEDA ◽  
Makoto HIURA ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Visceral Fat ◽  
Serum Insulin ◽  
Obese Children ◽  
Fat Accumulation ◽  
Visceral Fat Accumulation

Autonomic dysfunction and circadian blood pressure variations in people with impaired glucose tolerance

2013 ◽  
Vol 30 (3) ◽  
pp. 358-362 ◽  
Author(s):  
Z. Putz ◽  
N. Németh ◽  
I. Istenes ◽  
T. Martos ◽  
R. A. Gandhi ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Glucose Tolerance ◽  
Impaired Glucose Tolerance ◽  
Autonomic Dysfunction ◽  
Circadian Blood Pressure

scholarly journals The buckwheat iminosugar D-fagomine attenuates sucrose-induced steatosis and hypertension in rats

2020 ◽  
Vol 79 (OCE2) ◽  
Author(s):  
Sara Ramos-Romero ◽  
Mercè Hereu ◽  
Lidia Atienza ◽  
Susana Amézqueta ◽  
Josefina Casas ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Adipose Tissue ◽  
Uric Acid ◽  
Glucose Tolerance ◽  
Impaired Glucose Tolerance ◽  
Visceral Fat ◽  
Molecular Mechanisms ◽  
Fat Deposition ◽  
Oral Glucose ◽  
Standard Diet

AbstractD-Fagomine (1,2 dideoxynojirimycin) is an iminosugar, a carbohydrate analogue that includes an endocyclic nitrogen instead of oxygen, that is naturally present in buckwheat and buckwheat-based foodstuffs. This study examines the long-term functional effect of d-fagomine on sucrose-induced factors of metabolic syndrome and explores possible molecular mechanisms behind its action. We evaluated Wistar Kyoto rats fed a standard diet were given a 35% sucrose (glucose/fructose) solution with d-fagomine (or not, for comparison) or mineral water (controls) for 24 weeks. The variables measured were body weight and energy intake; glucose tolerance (oral glucose tolerance test); plasma leptin concentration; plasma lipid profile; the populations of Bacteroidetes, Firmicutes, bacteroidales, clostridiales, enterobacteriales, and Escherichia coli in feces; blood pressure; urine uric acid and F2t isoprostanes (F2-IsoPs); perigonadal fat deposition and hepatic histology and diacylglycerols (DAGs) in liver and adipose tissue. We found that d-Fagomine reduced sucrose induced hypertension, urine uric acid, F2-IsoPs as markers of oxidative stress (OS), steatosis and liver DAGs (32:1, 32:2, 34:1 and 36:2) without affecting perigonadal (visceral) fat deposition or DAG levels in visceral adipose tissue. It showed a slight tendency to reduce sugar induced impaired glucose tolerance. d-Fagomine also promoted excretion of enterobacteriales generated by the dietary intervention. We postulate that fructose increases visceral fat deposition independently of liver de novo liposynthesis and that d-fagomine attenuates steatosis and blood pressure mainly by reducing liver fructose levels. The reduction of blood pressure may be associated with an effect on uric acid synthesis while the reduced levels of selected active liver DAGs may explain the weak effect on sucrose-induced impaired glucose tolerance, which may be primarily induced by visceral fat deposition. In conclusion, the increased populations of excreted enterobacteriales may be connected to the levels of excreted uric acid. d-Fagomine counteracts sucrose-induced steatosis and hypertension presumably by reducing the postprandial levels of fructose in the liver as a consequence of intestinal sucrase inhibition.

Correlations of visceral fat accumulation and atherosclerosis in Japanese patients with type 2 diabetes mellitus

Metabolism ◽  
2008 ◽  
Vol 57 (2) ◽  
pp. 280-284 ◽  
Author(s):  
Futoshi Anan ◽  
Takayuki Masaki ◽  
Yoshikazu Umeno ◽  
Tetsu Iwao ◽  
Hidetoshi Yonemochi ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Visceral Fat ◽  
Japanese Patients ◽  
Fat Accumulation ◽  
Visceral Fat Accumulation
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