scholarly journals Incidence of Type 1 Diabetes Has Doubled in Rome and the Lazio Region in the 0- to 14-Year Age-Group: A 6-Year Prospective Study (2004-2009)

Diabetes Care ◽  
2010 ◽  
Vol 33 (11) ◽  
pp. e140-e140 ◽  
Author(s):  
C. Bizzarri ◽  
P. I. Patera ◽  
C. Arnaldi ◽  
S. Petrucci ◽  
M. L. M. Bitti ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Prospective Study ◽  
Age Group ◽  
Lazio Region ◽  
Group A

Decreased Incidence of Type 1 Diabetes in Young Finnish Children

2020 ◽  
Author(s):  
Anna Parviainen ◽  
Anna But ◽  
Heli Siljander ◽  
Mikael Knip ◽  
the Finnish Pediatric Diabetes Register
Keyword(s):  
Type 1 Diabetes ◽  
Young Children ◽  
Age Groups ◽  
Incidence Rates ◽  
Islet Autoimmunity ◽  
Disease Rate ◽  
Age Group ◽  
Group A ◽  
Design And Methods

OBJECTIVE <p>The incidence of type 1 diabetes has been rising for decades, particularly among young children. Between 2006 and 2011 the incidence rate reached a plateau in Finland. In this observational register-based cohort study, we assess recent trends in the disease rate in Finnish children.</p> <p>RESEARCH DESIGN AND METHODS</p> <p>Based on data from the Finnish Pediatric Diabetes Register, we studied the incidence of type 1 diabetes among children under the age of 15 years between 2003 and 2018. We assessed sex-specific incidence rates (IRs) per 100,000 person years (PY) by 4-year time periods in three age groups (0.50–4.99, 5.00–9.99, and 10.00–14.99 years).</p> <p>RESULTS</p> <p>Among the 7,871 children with newly diagnosed type 1 diabetes, the median age at diagnosis increased from 7.88 to 8.33 (<i>P </i>= 0.001), while the overall IR decreased from 57.9/100,000 PY in 2003–2006 to 52.2/100,000 PY in 2015–2018, yielding an IR ratio (IRR) of 0.90 (95% CI 0.85–0.96, <i>P </i>= 0.001). This decline was mainly due to the decrease in the youngest age group [IRR 0.77 (95% CI 0.68–0.87); <i>P </i>< 0.001], being significant both among males and females. In the middle age group, a significant decrease was observed only among females. No changes were observed in the oldest children.</p> <p>CONCLUSIONS</p> <p>The incidence of type 1 diabetes decreased among young Finnish children between 2003 and 2018. Current findings imply that environmental factors driving the immune system towards islet autoimmunity are changing in young children.</p>

A 10-year (1996-2005) prospective study of the incidence of Type 1 diabetes in Moscow in the age group 0-14 years

2008 ◽  
Vol 25 (8) ◽  
pp. 956-959 ◽  
Author(s):  
E. A. Pronina ◽  
E. E. Petraikina ◽  
M. B. Antsiferov ◽  
O.V. Duchareva ◽  
A. Petrone ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Prospective Study ◽  
Age Group

scholarly journals Decreased Incidence of Type 1 Diabetes in Young Finnish Children

2020 ◽  
Author(s):  
Anna Parviainen ◽  
Anna But ◽  
Heli Siljander ◽  
Mikael Knip ◽  
the Finnish Pediatric Diabetes Register
Keyword(s):  
Type 1 Diabetes ◽  
Young Children ◽  
Age Groups ◽  
Incidence Rates ◽  
Islet Autoimmunity ◽  
Disease Rate ◽  
Age Group ◽  
Group A ◽  
Design And Methods

OBJECTIVE <p>The incidence of type 1 diabetes has been rising for decades, particularly among young children. Between 2006 and 2011 the incidence rate reached a plateau in Finland. In this observational register-based cohort study, we assess recent trends in the disease rate in Finnish children.</p> <p>RESEARCH DESIGN AND METHODS</p> <p>Based on data from the Finnish Pediatric Diabetes Register, we studied the incidence of type 1 diabetes among children under the age of 15 years between 2003 and 2018. We assessed sex-specific incidence rates (IRs) per 100,000 person years (PY) by 4-year time periods in three age groups (0.50–4.99, 5.00–9.99, and 10.00–14.99 years).</p> <p>RESULTS</p> <p>Among the 7,871 children with newly diagnosed type 1 diabetes, the median age at diagnosis increased from 7.88 to 8.33 (<i>P </i>= 0.001), while the overall IR decreased from 57.9/100,000 PY in 2003–2006 to 52.2/100,000 PY in 2015–2018, yielding an IR ratio (IRR) of 0.90 (95% CI 0.85–0.96, <i>P </i>= 0.001). This decline was mainly due to the decrease in the youngest age group [IRR 0.77 (95% CI 0.68–0.87); <i>P </i>< 0.001], being significant both among males and females. In the middle age group, a significant decrease was observed only among females. No changes were observed in the oldest children.</p> <p>CONCLUSIONS</p> <p>The incidence of type 1 diabetes decreased among young Finnish children between 2003 and 2018. Current findings imply that environmental factors driving the immune system towards islet autoimmunity are changing in young children.</p>

scholarly journals Decreased Incidence of Type 1 Diabetes in Young Finnish Children

2020 ◽  
Author(s):  
Anna Parviainen ◽  
Anna But ◽  
Heli Siljander ◽  
Mikael Knip ◽  
the Finnish Pediatric Diabetes Register
Keyword(s):  
Type 1 Diabetes ◽  
Young Children ◽  
Age Groups ◽  
Incidence Rates ◽  
Islet Autoimmunity ◽  
Disease Rate ◽  
Age Group ◽  
Group A ◽  
Design And Methods

OBJECTIVE <p>The incidence of type 1 diabetes has been rising for decades, particularly among young children. Between 2006 and 2011 the incidence rate reached a plateau in Finland. In this observational register-based cohort study, we assess recent trends in the disease rate in Finnish children.</p> <p>RESEARCH DESIGN AND METHODS</p> <p>Based on data from the Finnish Pediatric Diabetes Register, we studied the incidence of type 1 diabetes among children under the age of 15 years between 2003 and 2018. We assessed sex-specific incidence rates (IRs) per 100,000 person years (PY) by 4-year time periods in three age groups (0.50–4.99, 5.00–9.99, and 10.00–14.99 years).</p> <p>RESULTS</p> <p>Among the 7,871 children with newly diagnosed type 1 diabetes, the median age at diagnosis increased from 7.88 to 8.33 (<i>P </i>= 0.001), while the overall IR decreased from 57.9/100,000 PY in 2003–2006 to 52.2/100,000 PY in 2015–2018, yielding an IR ratio (IRR) of 0.90 (95% CI 0.85–0.96, <i>P </i>= 0.001). This decline was mainly due to the decrease in the youngest age group [IRR 0.77 (95% CI 0.68–0.87); <i>P </i>< 0.001], being significant both among males and females. In the middle age group, a significant decrease was observed only among females. No changes were observed in the oldest children.</p> <p>CONCLUSIONS</p> <p>The incidence of type 1 diabetes decreased among young Finnish children between 2003 and 2018. Current findings imply that environmental factors driving the immune system towards islet autoimmunity are changing in young children.</p>

scholarly journals Plasma Lipoproteins and Preeclampsia in Women with Type 1 Diabetes: A Prospective Study

2012 ◽  
Vol 97 (5) ◽  
pp. 1752-1762 ◽  
Author(s):  
Arpita Basu ◽  
Petar Alaupovic ◽  
Mingyuan Wu ◽  
Alicia J. Jenkins ◽  
Yongxin Yu ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Prospective Study ◽  
Plasma Lipoproteins ◽  
A Prospective Study

scholarly journals Near-normoglycaemia and development of neuropathy: a 24-year prospective study from diagnosis of type 1 diabetes

BMJ Open ◽  
2015 ◽  
Vol 5 (6) ◽  
pp. e006559 ◽  
Author(s):  
Dan Ziegler ◽  
Margarete Behler ◽  
Maria Schroers-Teuber ◽  
Michael Roden
Keyword(s):  
Type 1 Diabetes ◽  
Prospective Study
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