scholarly journals Long-Term Prognosis of Diabetic Patients With Critical Limb Ischemia: A population-based cohort study

Diabetes Care ◽  
2009 ◽  
Vol 32 (5) ◽  
pp. 822-827 ◽  
Author(s):  
E. Faglia ◽  
G. Clerici ◽  
J. Clerissi ◽  
L. Gabrielli ◽  
S. Losa ◽  
...  
Keyword(s):  
Cohort Study ◽  
Critical Limb Ischemia ◽  
Limb Ischemia ◽  
Population Based ◽  
Diabetic Patients ◽  
Long Term Prognosis

Long-term prognosis of diabetic patients with critical limb ischemia after endovascular therapy

2016 ◽  
Vol 62 (5) ◽  
pp. 28-29
Author(s):  
Ann M. Gorbacheva ◽  
Zera N. Abdulvapova ◽  
Gagik R. Galstyan ◽  
Olga N. Bondarenko ◽  
Natalya L. Ayubova ◽  
...  
Keyword(s):  
Critical Limb Ischemia ◽  
Limb Ischemia ◽  
Arterial Blood Flow ◽  
Diabetic Patients ◽  
Cumulative Survival ◽  
Group A ◽  
Long Term Prognosis ◽  
Group B

Introduction. Critical limb ischemia (CLI) occurs approximately 20 times more frequently among diabetic patients. Frequency of amputations is higher too. Main treatment goal in these situations is in reconstruction of arterial blood flow with bypass surgery or endovascular interventions. Nevertheless, long-term prognosis of survival, limb preservation and life quality among Russian patients that underwent this therapy remains unclear, as well as influencing risk factors.The aim of the study was to evaluate the long-term prognosis in diabetic patients with critical limb ischemia (CLI) after peripheral angioplasty with active and nonactive follow-up period.Methods. 81 diabetic patients with CLI underwent PTA in 88 limbs. Patients were divided into 2 groups: group A (n = 51) – with active follow up (FU) period (visits every 3-6 months during 5 years) and group B (n = 30) - without active FU period (the second visit in our center was performed in 5 years after PTA). Diagnosis and treatment of CLI were based on recommendation of TASC II. The primary outcome was cumulative survival, secondary outcome were cases of repeat PTA and major amputations (MA) after 5 years after surgery.Results. Only 44 (86%) patients from group A finished FU period. There were 37 (46%) men, with mean age 64,1[54-68] years, mean HbA1c 7,9±1,4%, mean duration of diabetes 16,5[0,8-43] years, diabetes type 1/2 - 8/73 (90% of type 2). 82% had arterial hypertension, 5% - strokes, 18,5% - myocardial infarction. Chronical kidney disease of stage 1-2 was detected in 55,5%, stage 3-5 – in 30,8%. Anemia was diagnosed in 67,5%, arrhythmias – in 7,4%. 49,3% of patients suffered from diabetic retinopathy. Patients from both groups were comparable in comorbidities, severity of lower limb artery obstruction’s and degree of tissue damage (p<0,05): peripheral arterial disease (PAD) 4-6 classes according Graziani classification in both groups was in 75(93%) cases; Rutherford classification in both groups: 4 category-12(15%), 5category in 43(53%), and 6 category in 29(31%) patients. Repeat PTA was performed in group A in 15 (35%), in group B in 5(16%) cases. There were major amputations in groups: A-4(9%) vs group B – 4(12%) (log-rank, p<0,05). Cumulative survival in groups: A-80%, in group B-67%. (log-rank, p<0,05).Conclusion. CLI in diabetic patients is accompanied by different complications and is characterized by severe morphological lesions of the lower limbs arteries and soft tissue lesions. Active FU period have advantages in diabetic patients with CLI after PTA: timely done reinterventions with decrease the risk of major amputations and cumulative survival. 

scholarly journals Determinants of Long‐Term Outcomes and Costs in the Management of Critical Limb Ischemia: A Population‐Based Cohort Study

2018 ◽  
Vol 7 (16) ◽  
Author(s):  
Jihad A. Mustapha ◽  
Barry T. Katzen ◽  
Richard F. Neville ◽  
Robert A. Lookstein ◽  
Thomas Zeller ◽  
...  
Keyword(s):  
Cohort Study ◽  
Critical Limb Ischemia ◽  
Limb Ischemia ◽  
Population Based ◽  
Long Term Outcomes

Long-Term Clinical Outcomes of Infrapopliteal Drug-Eluting Stent Placement for Critical Limb Ischemia in Diabetic Patients

2015 ◽  
Vol 26 (10) ◽  
pp. 1423-1430 ◽  
Author(s):  
Stavros Spiliopoulos ◽  
Vasiliki Theodosiadou ◽  
Konstantinos Katsanos ◽  
Panagiotis Kitrou ◽  
George C. Kagadis ◽  
...  
Keyword(s):  
Clinical Outcomes ◽  
Critical Limb Ischemia ◽  
Stent Placement ◽  
Limb Ischemia ◽  
Drug Eluting Stent ◽  
Diabetic Patients ◽  
Drug Eluting

scholarly journals Outcome After Leg Bypass Surgery for Critical Limb Ischemia Is Poor in Patients With Diabetes: A population-based cohort study

Diabetes Care ◽  
2008 ◽  
Vol 31 (5) ◽  
pp. 887-892 ◽  
Author(s):  
J. Malmstedt ◽  
K. Leander ◽  
E. Wahlberg ◽  
L. Karlstrom ◽  
L. Alfredsson ◽  
...  
Keyword(s):  
Cohort Study ◽  
Critical Limb Ischemia ◽  
Bypass Surgery ◽  
Limb Ischemia ◽  
Population Based ◽  
Patients With Diabetes

Long-Term Outcomes of Direct and Indirect Below-The-Knee Open Revascularization Based on the Angiosome Concept in Diabetic Patients with Critical Limb Ischemia

2014 ◽  
Vol 28 (4) ◽  
pp. 983-989 ◽  
Author(s):  
Anne Lejay ◽  
Yannick Georg ◽  
Elvira Tartaglia ◽  
Sébastien Gaertner ◽  
Bernard Geny ◽  
...  
Keyword(s):  
Critical Limb Ischemia ◽  
Limb Ischemia ◽  
Diabetic Patients ◽  
Long Term Outcomes ◽  
Below The Knee

scholarly journals Long-Term Outcomes of Diabetic Patients With Critical Limb Ischemia Followed in a Tertiary Referral Diabetic Foot Clinic

Diabetes Care ◽  
2010 ◽  
Vol 33 (5) ◽  
pp. 977-982 ◽  
Author(s):  
L. Uccioli ◽  
R. Gandini ◽  
L. Giurato ◽  
S. Fabiano ◽  
E. Pampana ◽  
...  
Keyword(s):  
Critical Limb Ischemia ◽  
Diabetic Foot ◽  
Limb Ischemia ◽  
Diabetic Patients ◽  
Long Term Outcomes ◽  
Tertiary Referral ◽  
Foot Clinic

scholarly journals Long-Term Prognosis of Asthma-Bronchiectasis Overlapped Patients: A Nationwide Population-Based Cohort Study

2021 ◽  
Vol 13 (6) ◽  
pp. 908
Author(s):  
Sang Chul Lee ◽  
Kang Ju Son ◽  
Hye-Jung Park ◽  
Ji Ye Jung ◽  
Seon Cheol Park ◽  
...  
Keyword(s):  
Cohort Study ◽  
Population Based ◽  
Long Term Prognosis
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