scholarly journals Markedly Blunted Metabolic Effects of Fructose in Healthy Young Female Subjects Compared With Male Subjects

Diabetes Care ◽  
2008 ◽  
Vol 31 (6) ◽  
pp. 1254-1256 ◽  
Author(s):  
C. Couchepin ◽  
K.-A. Le ◽  
M. Bortolotti ◽  
J. A. da Encarnacao ◽  
J.-B. Oboni ◽  
...  
Keyword(s):  
Young Female ◽  
Metabolic Effects ◽  
Male Subjects ◽  
Healthy Young Female ◽  
Female Subjects

Reduced Coenzyme Q10 Decreases Urinary 8-Oxo-7,8-Dihydro-2′-Deoxyguanosine Concentrations in Healthy Young Female Subjects

2015 ◽  
Vol 18 (8) ◽  
pp. 835-840 ◽  
Author(s):  
Kimiko Ito ◽  
Chigusa Watanabe ◽  
Akari Nakamura ◽  
Saeko Oikawa-Tada ◽  
Mariko Murata
Keyword(s):  
Coenzyme Q10 ◽  
Young Female ◽  
Healthy Young Female ◽  
Female Subjects

THE EFFECT OF ALTERATION OF THYROXINE BINDING CAPACITY ON THE DIALYZABLE AND ABSOLUTE FRACTIONS OF TRIIODOTHYRONINE IN CIRCULATION

1973 ◽  
Vol 72 (2) ◽  
pp. 265-271 ◽  
Author(s):  
J. H. Dussault ◽  
D. A. Fisher ◽  
J. T. Nicoloff ◽  
V. V. Row ◽  
R. Volpe
Keyword(s):  
Correlation Coefficient ◽  
Inverse Relationship ◽  
Binding Capacity ◽  
Hormone Concentration ◽  
Thyroxine Binding Globulin ◽  
Serum Thyroxine ◽  
A Value ◽  
The Mean ◽  
Male Subjects ◽  
Female Subjects

ABSTRACT In order to determine the effect of alterations in binding capacity of thyroxine binding globulin (TBG) on triiodothyronine (T3) metabolism, studies were conducted in 10 patients with idiopathically low (7 subjects) or elevated (3 subjects) TBG levels and 10 subjects given norethandrolone (7 male subjects) or oestrogen (3 female subjects). Measurements of serum thyroxine (T4) concentration, maximal T4 binding capacity, serum T3 concentration and per cent dialyzable T3 were conducted. Serum T3 was measured both by chemical and radioimmunoassay methods. In patients with idiopathically low TBG, the mean serum T4 concentration was low (2.4 μg/100 ml), the mean serum T3 level low (55 ng/100 ml), the mean per cent dialyzable T3 increased (0.52%), and the calculated free T3 concentration normal (186 pg/100 ml). In patients with idiopathically high TBG levels the mean T4 concentration was high (10.3 μg/100 ml), the mean T3 level slightly elevated (127 ng/100 ml), the% dialyzable T3 low (0.10%) and the calculated free T3 concentration low normal (123 pg/100 ml). The correlation coefficient between the per cent dialyzable T3 and maximal TBG binding capacity in the 20 subjects was 0.68, a value significant at the P < 0.01 level. Thus, alterations in binding capacity of TBG seem to influence T3 and T4 metabolism similarly; the inverse relationship between the % of dialyzable hormone and total hormone concentration tends to keep the absolue levels of free hormones stable.

scholarly journals Mood and Metabolic Health Status of Elderly Osteoporotic Patients in Korea: A Cross-Sectional Study of a Nationally Representative Sample

Healthcare ◽  
2021 ◽  
Vol 9 (1) ◽  
pp. 77
Author(s):  
Hyen Chul Jo ◽  
Gu-Hee Jung ◽  
Seong-Ho Ok ◽  
Ji Eun Park ◽  
Jong Chul Baek
Keyword(s):  
Abdominal Obesity ◽  
Bone Health ◽  
Elderly Women ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Standard Procedures ◽  
Nationally Representative ◽  
Male Subjects ◽  
Female Subjects

This study aimed to investigate the association between osteoporosis and comorbidity, which are very common in Korea, and develop a treatment strategy to improve bone health based on the findings of the Korean National Health and Nutritional Examination Surveys (KNHANES). This study was based on data obtained from 4060 subjects (1755 males, 2305 females) aged above 60 years in the KNHANES (2016–2017). Well-trained medical staff performed the standard procedures and measured several variables including height, weight, and waist circumference. Interviews and laboratory tests were based on the diagnosis of hyperuricemia, dyslipidemia, type 2 diabetes mellitus (T2DM), osteoporosis, and depression. Comorbidities were defined as a self-reported physician diagnosis. The association of osteoporosis with depression and metabolic disease was assessed statistically using the complex sample analysis method of SPSS. The presence of osteoporosis, dyslipidemia, T2DM, hyperuricemia, obesity, abdominal obesity, and depression was 6.1 ± 0.5%, 15.2 ± 0.7%, 6.5 ± 0.4%, 13.4 ± 0.7%, 30.8 ± 0.8%, 19.4 ± 0.9%, 4.0 ± 0.2%, respectively. After adjusted by age, osteoporotic subjects were significance in the presence of abdominal obesity (p = 0.024, OR 0.80), hyperuricemia (p = 0.013, OR 0.68), dyslipidemia (p < 0.001, OR 1.84), and depression (p < 0.001, OR 2.56), respectively. Subgroup analyses showed dyslipidemia (female subjects, p < 0.001, OR 1.04; male subjects, p = 0.94, OR 1.09) and depression (female subjects, p < 0.001, OR 1.76; male subjects, p = 0.51, OR 0.62) were associated with osteoporotic female subjects but not in male subjects. The comorbidity of dyslipidemia and depression in female subjects was associated with osteoporosis and an odds ratio was 13.33 (95% CI: 8.58–20.71) (p < 0.001). The comorbidity of abdominal obesity (female subjects, p = 0.75, OR 0.97; male subjects, p = 0.94, OR 1.02) and hyperuricemia (female subjects, p = 0.27, OR 0.81; male subjects p = 0.07, OR 0.35) was not associated with osteoporosis in both Subgroup. The result of this study shows a strong dependency of comorbidity with dyslipidemia and depression in elderly women with osteoporosis. Therefore, efforts to improve dyslipidemia and depression might prevent compromised bone health.

scholarly journals Eating behavior affects cardio-metabolic risk in high school teenagers in a developing country

2020 ◽  
Vol 29 (1) ◽  
pp. 71-81
Author(s):  
Rita Suhadi ◽  
Phebe Hendra ◽  
Dita Maria Virginia ◽  
Christianus Heru Setiawan
Keyword(s):  
Risk Factors ◽  
Heart Rate ◽  
Waist Circumference ◽  
Eating Behavior ◽  
Eating Behaviors ◽  
Metabolic Risk Factors ◽  
Metabolic Risk ◽  
Cross Sectional ◽  
Male Subjects ◽  
Female Subjects

BACKGROUND Modernization negatively changes lifestyle, characterized by excessive eating and reduced energy consumption, and concurrently increases the cardiometabolic risk. This study was aimed to evaluate the association between eating behavior and cardio-metabolic risk factors including body mass index (BMI) in percentile, blood pressure (BP) in percentile, waist circumference, and heart rate in total subjects and gender sub-groups. METHODS This analytical cross-sectional study was done from July to November 2018. High schools in four provinces of Indonesia and students were selected using purposive sampling. Subjects’ profiles were collected from interview and cardio-metabolic parameters were measured at the study sites. Data were analyzed with chi-square and independent t-test. RESULTS Subjects who were overweight/obese and had high BP accounted for 27.1% and 9.3–12.0% of the total subjects (n = 768), respectively. Subjects who having breakfast tended to have lower BMI (p = 0.006), and the lower consumption of western meals had lower heart rate (p = 0.02). Male subjects had more meal frequency and had less quantity of snacks than female subjects (p<0.001). Male subjects with routine intake of vegetables had low heart rate (p = 0.03). Female subjects with routine breakfast had better BMI (p<0.001), and lower diastolic BP (p = 0.004) and waist circumference (p = 0.02), whereas those who consumed Western meals had higher heart rate (p = 0.046) and waist circumference (p = 0.001). CONCLUSIONS Eating behaviors are likely to affect cardio-metabolic risk factors, and the effects vary within gender groups.

The five‐factor personality model in applied settings

1994 ◽  
Vol 8 (1) ◽  
pp. 1-11 ◽  
Author(s):  
Itzhak Montag ◽  
Joseph Levin
Keyword(s):  
Factor Analysis ◽  
Personality Inventory ◽  
The Other ◽  
Factor Solution ◽  
Male And Female ◽  
Neo Personality Inventory ◽  
Clear Cut ◽  
Five Factors ◽  
Male Subjects ◽  
Female Subjects

Two studies of the Revised NEO‐Personality Inventory (NEO‐PI‐R) conducted on two different applicant samples (one consisting of 539 female subjects and the other consisting of 396 male subjects) are reported. Factor analysis of the female sample yielded a five‐factor solution, highly congruent with the factors presented by Costa, McCrae and Dye (1991). Results of the male data were less clear‐cut, yielding four to five factors which were moderately congruent with the American data. The combined male and female sample showed again high congruence coefficients. Various minor deviations in the location of the facet variables are discussed.

scholarly journals Arch Widths in Class II-2 Adults Compared to Adults with Class II-1 and Normal Occlusion

2007 ◽  
Vol 77 (5) ◽  
pp. 837-844 ◽  
Author(s):  
Joel Huth ◽  
Robert Newton Staley ◽  
Richard Jacobs ◽  
Harold Bigelow ◽  
Jane Jakobsen
Keyword(s):  
Class Ii ◽  
White Americans ◽  
Gender Dimorphism ◽  
Arch Width ◽  
Normal Occlusion ◽  
Division 1 ◽  
History Of ◽  
Division 2 ◽  
Male Subjects ◽  
Female Subjects

Abstract Objective: To compare (1) arch widths in adults with Class II division 2 (II-2), Class II division 1 (II-1), and Class I normal occlusions, (2) genders, (3) gender dimorphism, (4) differences between maxillary and mandibular arch widths, and to (5) develop adult norms for arch widths. Materials and Methods: Subjects were white Americans with no history of orthodontic treatment. Arch width dimensions measured were: intercanine, intermolar, and molar alveolar in both arches. Analysis of variance (ANOVA) and Duncan's test were used to compare groups. Results: Comparison of pooled genders showed the II-2 group had maxillary arch widths significantly smaller than the normal occlusions and significantly larger than the II-1 group. All groups had similar mandibular intercanine and alveolar widths. The II-2 and II-1 groups had similar mandibular intermolar widths, both significantly smaller than normal occlusions. The II-2 group had a maxillary/mandibular intermolar difference significantly smaller than the normal occlusions, and significantly less negative than the II-1 group. Gender comparisons in two of six widths showed normal and II-2 male subjects were similar, and in six of six widths normal and II-2 female subjects were similar; in five of six widths II-2 and II-1 male and female subjects were similar. Gender dimorphism occurred in five of six widths in normal occlusions, four of six widths in II-2, and one of six widths in II-1. Conclusions: Arch width dimensions of II-2 subjects were intermediate between normal and II-1 occlusions. In both Class II malocclusions, the process that narrows arch widths was more pronounced in male than in female subjects.

Two-Year Repeated Study on Health Effect of Net-Step Exercise Program in Community-Dwelling Older Persons

2021 ◽  
Vol 7 (2) ◽  
Author(s):  
Mori M ◽  
◽  
Seko T ◽  
Ogawa S ◽  
Kitazawa K ◽  
...  
Keyword(s):  
Repeated Measures ◽  
Older Persons ◽  
Smoking Status ◽  
Health Effect ◽  
Exercise Program ◽  
Community Dwelling ◽  
Confounding Variables ◽  
One Year ◽  
Male Subjects ◽  
Female Subjects

Background: A light-burden and indoor physical exercise program called Net-Step Exercise (NSE) has been developed in Hokkaido, Japan. Conducting the two-year repeated survey with the Kihon Checklist (KCL) for the same older subjects living in a rural area of Hokkaido where a relatively large proportion of the older persons have participated in NSE activity, we assessed the effectiveness of NSE activity. Methods: The whole of 3,155 community-dwelling persons aged from 75 years to 79 years in 8 towns were the candidates of the study subjects, and 2,183 subjects (69.2%) responded to the first survey (2018 Survey), answering the questions about both frequency of participation in NSE and each item in KCL. The same survey (2019 Survey) was conducted one year later, and completed by 1,956 subjects (93.3%), excluding 25 dead persons or 60 persons who had moved away from the community during the year. In the 2018 Survey as well as the 2019 Survey, Adjusted Odds Ratio (AOR) and its 95% confidence interval (95%CI) of each sub-category of KCL for NSE Participants compared with NSE Non-participants was calculated with unconditional logistic regression by sex, adjusting for age, smoking status, and other potentially confounding variables. Repeated-measures Analysis of Variance (ANOVA) was also applied by sex. Results: Significantly reduced risk (AOR with 95% CI) was observed in NSE participants in difficulty in activities of daily living in the male subjects in the 2018 Survey (0.64, 0.42-0.98) and in the 2019 Survey (0.50, 0.32-0.79), as well as in the female subjects in the 2018 Survey (0.52, 0.38-0.70) and in the 2019 Survey (0.46, 0.33-0.65), houseboundness in the female subjects in the 2018 Survey (0.42, 0.29-0.60) and in the 2019 Survey (0.70, 0.51-0.96), impaired cognitive function in the male subjects in the 2018 Survey (0.58, 0.36-0.92), and depressive status in the female subjects in the 2018 Survey (0.66, 0.49-0.88). Significant findings were also shown in most of the above four sub-categories by analysis with repeated-measures ANOVA. Conclusion: Either performance of NSE itself or participation in the program, or both, may promote healthy status in the older persons.

The acute effects of differential dietary fatty acids on human skeletal muscle pyruvate dehydrogenase activity

2008 ◽  
Vol 104 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Nicolette S. Bradley ◽  
George J. F. Heigenhauser ◽  
Brian D. Roy ◽  
Elizabeth M. Staples ◽  
J. Greig Inglis ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Pyruvate Dehydrogenase ◽  
Dietary Fatty Acids ◽  
Metabolic Effects ◽  
Moderate Intensity ◽  
Acute Effects ◽  
Moderate Intensity Exercise ◽  
Important Regulator ◽  
Male Subjects ◽  
Muscle Biopsies

Pyruvate dehydrogenase (PDH) is an important regulator of carbohydrate oxidation during exercise, and its activity can be downregulated by an increase in dietary fat. The purpose of this study was to determine the acute metabolic effects of differential dietary fatty acids on the activation of the PDH complex (PDHa activity) at rest and at the onset of moderate-intensity exercise. University-aged male subjects ( n = 7) underwent two fat-loading trials spaced at least 2 wk apart. Subjects consumed ∼300 g saturated (SFA) or n-6 polyunsaturated fatty acid (PUFA) fat over the course of 5 h. Following this, participants cycled at 65% of their maximum oxygen uptake for 15 min. Muscle biopsies were taken before and following fat loading and at 1 min exercise. Plasma free fatty acids increased from 0.15 ± 0.07 to 0.54 ± 0.19 mM over 5 h with SFA and from 0.11 ± 0.04 to 0.35 ± 0.13 mM with n-6 PUFA and were significantly lower throughout the n-6 PUFA trial. PDHa activity was unchanged following fat loading but increased at the onset of exercise in the SFA trial, from 1.18 ± 0.27 to 2.16 ± 0.37 mmol·min−1·kg wet wt−1. This effect was negated in the n-6 PUFA trial (1.04 ± 0.20 to 1.28 ± 0.36 mmol·min−1·kg wet wt−1). PDH kinase was unchanged in both trials, suggesting that the attenuation of PDHa activity with n-6 PUFA was a result of changes in the concentrations of intramitochondrial effectors, potentially intramitochondrial NADH or Ca2+. Our findings suggest that attenuated PDHa activity contributes to the preferential oxidation of n-6 PUFA during moderate-intensity exercise.

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