696-P: Vasodilatory Response of the Muscular Artery Was Improved to Sheer Stress, but Paradoxically Decreased to Endothelium-Dependent Vasodilator in Diet and Aerobic Exercise in Type 2 Diabetes

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 696-P
Author(s):  
KYUNG AH HAN ◽  
BOYEON YANG ◽  
KYUNGWAN MIN
Keyword(s):  
Type 2 Diabetes ◽  
Aerobic Exercise ◽  
Muscular Artery ◽  
Vasodilatory Response ◽  
Sheer Stress

Impact of fasting and postprandial state on plasma carnitine concentrations during aerobic exercise in type 2 diabetes

2007 ◽  
Vol 44 (3) ◽  
pp. 114-120 ◽  
Author(s):  
A. Ferland ◽  
T. L. Broderick ◽  
A. Nadeau ◽  
S. Simard ◽  
J. Martin ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Aerobic Exercise ◽  
Plasma Carnitine ◽  
Postprandial State

Abstract P137: Aerobic, Resistance or Combination Exercise Training does not Reduce C-Reactive Protein Levels in Individuals with Type 2 Diabetes

Circulation ◽  
2012 ◽  
Vol 125 (suppl_10) ◽  
Author(s):  
Damon L Swift ◽  
Neil M Johannsen ◽  
Conrad P Earnest ◽  
Steven N Blair ◽  
Timothy S Church
Keyword(s):  
Type 2 Diabetes ◽  
Exercise Training ◽  
Aerobic Exercise ◽  
Fat Mass ◽  
Fasting Glucose ◽  
Aerobic Exercise Training ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein

Introduction: Type 2 diabetes is associated with elevated C-reactive protein levels (CRP), which is an independent risk factor for cardiovascular disease. Aerobic exercise training especially with weight/adiposity reduction has been shown to improve CRP, however few studies have evaluated the effect of other exercise training modalities (aerobic, resistance or combination training) on CRP in individuals with type 2 diabetes. Hypothesis: We hypothesize that combination training will improve CRP to a greater extent than other modalities of exercise training, and change in CRP levels will be associated with changes in weight and adiposity. Methods: The present study is a secondary analysis of the Health Benefits of Aerobic and Resistance Training in Individuals with Type 2 Diabetes (HART-D) study. Participants (n=204) were randomized to aerobic exercise (aerobic), resistance exercise (resistance) or a combination of both (combination) for nine months. Results: Baseline CRP was correlated with fat mass, waist circumference, BMI, and inversely correlated with VO2 peak (p<0.05). CRP was not reduced in the aerobic (0.16 mg•L-1, 95% CI: -1.0, 1.3), resistance (-0.03 mg•L-1, 95% CI: -1.1, 1.0) or combination (-0.49 mg•L-1, 95% CI: -1.5 to 0.6) groups compared to control (0.35 mg•L-1, 95% CI: -1.0, 1.7). Change in CRP was associated with change in fasting glucose (r=0.20, p= 0.009), glycated hemoglobin (HbA1C) (r=0.21 p=0.005), and fat mass (r=0.19, p=0.016), but not change in fitness or weight (p > 0.05). Conclusions: In conclusion, aerobic, resistance or a combination of both did not reduce CRP levels in individuals with type 2 diabetes. However, exercise related improvements in HbA1C, fasting glucose, and fat mass were associated with reductions in CRP.

scholarly journals High-intensity exercise to promote accelerated improvements in cardiorespiratory fitness (HI-PACE): Study protocol for a randomized controlled trial

2019 ◽  
Author(s):  
Joshua E. McGee ◽  
Savanna G. Barefoot ◽  
Nicole R. Gniewek ◽  
Patricia M. Brophy ◽  
Angela Clark ◽  
...  
Keyword(s):  
Public Health ◽  
Type 2 Diabetes ◽  
African Americans ◽  
Aerobic Exercise ◽  
Cardiorespiratory Fitness ◽  
High Intensity ◽  
Controlled Trial ◽  
High Intensity Exercise ◽  
Moderate Intensity

Abstract Background African Americans have a disproportionate prevalence and incidence of type 2 diabetes compared to Caucasians. Recent evidence indicates low cardiorespiratory fitness (CRF) level, an independent risk factor for type 2 diabetes, is also more prevalent in African Americans than Caucasians. Numerous studies in Caucasian populations suggest vigorous exercise intensity may promote greater improvements in CRF and other type 2 diabetes risk factors (e.g. reduction of glucose/insulin levels, pulse wave velocity, body fat, etc.) than moderate intensity. However, current evidence comparing health benefits of different aerobic exercise intensities on type 2 diabetes risk factors in African Americans is negligible. This is clinically important as African Americans have a greater risk for type 2 diabetes and are less likely to meet public health recommendations for physical activity than Caucasians. The purpose of the High-Intensity exercise to Promote Accelerated improvements in CardiorEspiratory fitness (HI-PACE) study is to evaluate whether high-intensity aerobic exercise elicits greater improvements in CRF, insulin action, and arterial stiffness than moderate-intensity exercise in African Americans. Methods/Design­ A randomized controlled trial will be performed on overweight and obese (body mass index: 25-45 kg/m2) African Americans (35-65 years) (n=60). Participants will be randomized to moderate-intensity (MOD-INT) or high-intensity (HIGH-INT) aerobic exercise training, or a non-exercise control group (CON) for 24 weeks. Supervised exercise will be performed at a heart rate associated with 45-55% and 70-80% of VO2 max in the MOD-INT and the HIGH-INT groups, respectively, for an exercise dose of 600 MET-minutes/week (consistent with public health recommendations). The primary outcome is change in CRF. Secondary outcomes include change in insulin sensitivity (measured via an intravenous glucose tolerance test), skeletal muscle mitochondrial oxidative capacity (via near infrared spectroscopy), skeletal muscle measurements (i.e. citrate synthase, COX IV, GLUT-4, CPT-1, PGC1-α), arterial stiffness (via carotid-femoral pulse wave velocity), body fat, C-reactive protein, and psychological outcomes (quality of life/exercise enjoyment). Discussion The anticipated results of the HI-PACE study will provide vital information on the health effects of high-intensity exercise in African Americans. This study will advance health disparity research and has the potential to influence future public health guidelines for physical activity. Trial Registration ClinicalTrials.gov ID: NCT02892331. Registered on 8 September 2016, https://clinicaltrials.gov/ct2/show/NCT02892331

Effects of structured Aerobic Exercise on selected clinical profiles of patients with type 2 diabetes mellitus: A systematic review with meta-analysis

2021 ◽  
Vol 26 (1) ◽  
pp. 17
Author(s):  
EchezonaNelson Dominic Ekechukwu ◽  
NmachukwuIfeoma Ekechukwu ◽  
StellaUdumma Anwara ◽  
UkamakaGloria Mgbeojedo ◽  
OliveU Chijioke ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Systematic Review ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Aerobic Exercise ◽  
Meta Analysis ◽  
Clinical Profiles

scholarly journals Effects of activated vitamin D, alfacalcidol, and low-intensity aerobic exercise on osteopenia and muscle atrophy in type 2 diabetes mellitus model rats

PLoS ONE ◽  
2018 ◽  
Vol 13 (10) ◽  
pp. e0204857 ◽  
Author(s):  
Manabu Akagawa ◽  
Naohisa Miyakoshi ◽  
Yuji Kasukawa ◽  
Yuichi Ono ◽  
Yusuke Yuasa ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Vitamin D ◽  
Type 2 Diabetes Mellitus ◽  
Aerobic Exercise ◽  
Muscle Atrophy ◽  
Low Intensity

scholarly journals Effectiveness of resistance exercise compared to aerobic exercise without insulin therapy in patients with type 2 diabetes mellitus: a meta-analysis

2017 ◽  
Vol 21 (6) ◽  
pp. 400-415 ◽  
Author(s):  
Cybelle Nery ◽  
Silvia Regina Arruda De Moraes ◽  
Karyne Albino Novaes ◽  
Márcio Almeida Bezerra ◽  
Patrícia Verçoza De Castro Silveira ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Resistance Exercise ◽  
Insulin Therapy ◽  
Aerobic Exercise ◽  
Meta Analysis

Impact of treatment with glibenclamide or vildagliptin on glucose variability after aerobic exercise in type 2 diabetes: A randomized controlled trial

2018 ◽  
Vol 143 ◽  
pp. 184-193 ◽  
Author(s):  
Aline Fofonka ◽  
Patrícia Martins Bock ◽  
Karina Rabello Casali ◽  
Anderson Donelli da Silveira ◽  
Felipe Marques da Rosa ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Randomized Controlled Trial ◽  
Aerobic Exercise ◽  
Controlled Trial ◽  
Glucose Variability ◽  
Randomized Controlled
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