586-P: Characteristics of 24-Hour Urinary Electrolyte Excretion and Its Correlation with Renal Function in Type 2 Diabetics

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 586-P
Author(s):  
YANRU WANG ◽  
NAN LI ◽  
LE BU ◽  
HANG SUN ◽  
BING ZHU ◽  
...  
2021 ◽  
pp. 27-34
Author(s):  
Paulinus Jimmy Unung ◽  
Iya Eze Bassey ◽  
Mahmoud B Alhassan ◽  
Euphoria C. Akwiwu ◽  
Faith A. Effa ◽  
...  

Context: the role of vascular endothelial growth factor (VEGF) and pigment epithelium-derived factor (PEDF) on renal function of diabetics is unclear. Objective: This study investigated the relationship between VEGF, PEDF and urea, creatinine and estimated glomerular filtration rate (eGFR) in type 2 diabetics. Materials and Methods: 100 type 2 diabetics and 50 controls were recruited into this case-control study. Analytes were determined by standard methods. Statistical significance was set at p<0.05 and 95% Confidence interval.   Results: VEGF, PEDF (p=0.0001), urea (p=0.024) and creatinine (p=0.026) were significantly higher in diabetics than controls but eGFR was comparable (p>0.05) in both groups. VEGF and PEDF were comparable (p>0.05) in the diabetics with eGFR<60 ml/min and >60 ml/min. Renal function parameters did not correlate with either VEGF or PEDF. Conclusion: plasma VEGF and PEDF are higher in diabetics but there seem to be no association between renal function determinants and either VEGF and PEDF.


2016 ◽  
Vol 16 (9) ◽  
pp. 1-11
Author(s):  
Akinbodewa Akinwumi ◽  
Okunola Oluyomi ◽  
Adelusola Kayode ◽  
Sanusi Abefe ◽  
Arogundade Abiola ◽  
...  

2014 ◽  
Vol 13 (4) ◽  
pp. 406-410
Author(s):  
Priti Singh ◽  
Salman Khan ◽  
Rabindra Kumar Mittal

Background: Diabetes mellitus (DM) is characterized by some specific complications including diabetic nephropathy. Urea & creatinine are useful parameters to diagnose the renal function, despite some limitations. Objective: This study aimed to analyze the effect of hyperglycemic condition on the renal function parameters like serum urea and serum creatinine. Methods: It was a cross sectional study. To determine the incidence of kidney dysfunction in type 2 diabetics in Nepalgunj Medical College and Hospital, Nepalgunj, Nepal. Random blood samples were taken from 100 diabetic subjects and 100 non-diabetic controls between the period 1st February, 2012 to 31st January, 2013 for investigation of fasting plasma glucose (FPG), blood urea and serum creatinine. These biochemical parameters were determined by using a fully automated clinical chemistry analyzer. The comparison was done by using Student ‘t’ test. Results: Our findings showed that the level of blood urea (P<0.0128 Diabetic male and P?0.0082 Diabetic female) and serum creatinine (P<0.0001 Diabetic male and P?0.0187 Diabetic female) were significantly higher in type 2 diabetics as compared to non-diabetics in both male and female. There was no significant difference between diabetic male and female. High serum creatinine level was seen in males than females. Conclusion: In our study there was an increase of blood urea level in type 2 DM. Good control of blood glucose level is absolute requirement to prevent progressive renal impairment. DOI: http://dx.doi.org/10.3329/bjms.v13i4.20586 Bangladesh Journal of Medical Science Vol.13(4) 2014 p.406-410


2020 ◽  
Author(s):  
Ramla Mizouri ◽  
Hajer Zahra ◽  
Fatma Boukhayatia ◽  
Faten Mahjoub ◽  
Olfa Berriche ◽  
...  

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