183-LB: Prediction of Osteoporosis in Patients with Newly Diagnosed Type 2 Diabetes Based on Their Impaired Bone Turnover: A Retrospective Study in Chinese Population

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 183-LB
Author(s):  
LIGE SONG ◽  
HUIJUAN LI ◽  
YUHUA WEN ◽  
XIAOYA ZHANG ◽  
PEIPEI LIU
Keyword(s):  
Type 2 Diabetes ◽  
Retrospective Study ◽  
Bone Turnover ◽  
Chinese Population ◽  
Newly Diagnosed

scholarly journals Patients characteristics associated with better glycemic response to teneligliptin and metformin therapy in type 2 diabetes: a retrospective study

2018 ◽  
Vol 5 (2) ◽  
pp. 424
Author(s):  
Pradeep V. Gadge ◽  
Roshani P. Gadge ◽  
Nikita D. Paralkar
Keyword(s):  
Type 2 Diabetes ◽  
Body Mass Index ◽  
Retrospective Study ◽  
Blood Sugar ◽  
Therapeutic Effectiveness ◽  
Glycemic Response ◽  
Newly Diagnosed ◽  
Long Duration

Background: Teneligliptin was recently approved for type 2 diabetes (T2D) management in India and is used as monotherapy or in combination with different antidiabetic drugs. The aim of this study was to identify patients’ characteristics associated with better glycemic response to teneligliptin and metformin.Methods: A retrospective analysis of data was performed in patients of T2D with HbA1c above 7% who were treated with teneligliptin 20 mg/d as add on to metformin (500-100 mg/d) and whose follow-up data at 12-weeks was available. Fasting blood sugar (FBS) and post-prandial blood sugar (PPBS) changes were analysed.  Results: Among 66 patients included in analysis, mean age was 61.0±9.8 years and 53% were females. Median duration of diabetes was 2 years. At 12-weeks, a significant reduction PPBS was observed (mean change: -14.3 mg/dL, p=0.009) but not in FBS (mean change: -2.4 mg/dL, p=0.353). Among different patients’ characteristics, age ≤60 years (p=0.006), duration of ≤1 year (p=0.023), body-mass index ≥25 kg/m2 (p=0.009), presence of dyslipidemia (p=0.05) and absence of complications (p=0.012) were associated with significant reduction in PPBS but not in FBS.Conclusions: A younger, newly-diagnosed, obese T2D patients with dyslipidemia without any complications of diabetes can derive better therapeutic effectiveness from teneligliptin added to metformin. These findings need to be confirmed in large, prospective, long duration study.  

scholarly journals Association of dietary fiber intake with newly-diagnosed type 2 diabetes mellitus in middle-aged Chinese population

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Fubi Jin ◽  
Jinghong Zhang ◽  
Long Shu ◽  
Wei Han
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Dietary Fiber ◽  
Chinese Population ◽  
Newly Diagnosed ◽  
Fiber Intake ◽  
Middle Aged ◽  
Dietary Fiber Intake

Abstract Background Epidemiological evidence concerning dietary fiber on newly-diagnosed type 2 diabetes mellitus (T2DM) is sparse. Therefore, the purpose of this study was to investigate the relationship between dietary fiber intake and newly-diagnosed T2DM in a middle-aged Chinese population. Methods Using data from the Hangzhou Nutrition and Health Survey collected between June 2015 and December 2016, we investigated the associations between dietary patterns and the risk of chronic non- communicable diseases. Anthropometric measurements and samples collection for biochemical assays are conducted by the well-trained staff and nurse, respectively. Multivariable logistic regression analysis was used to analyze the effect of dietary fiber intake on the risk of newly-diagnosed T2DM in crude and adjusted models. Results Among 3250 participants, 182 (5.6%) people were identified as newly-diagnosed T2DM. Pearson correlation coefficients revealed a significant inverse association of total dietary fiber with BMI, SBP, DBP, HbA1c and LDL-C in all participants, participants with and without T2DM (P < 0.05). Compared with the study participants in the first quartile (Q1, the lowest consumption)of dietary fiber intake, participants in the fourth quartile (Q4) had a lower prevalence of newly-diagnosed T2DM(OR = 0.70; 95%CI:0.49-1.00; P < 0.05), after adjustment for potential confounders. Conclusions In this middle-aged Chinese population, higher intake of dietary fiber was significantly associated with lower risk of newly-diagnosed T2DM. However, our findings need to be confirmed in future large-scale prospective studies.

scholarly journals Markers of Bone Turnover and 25-Hydroxy Vitamin D in Women with Type 2 Diabetes and Newly Diagnosed Osteoporosis

2016 ◽  
Vol 23 (1) ◽  
Author(s):  
Raluca Nan ◽  
Adrian Cursaru ◽  
Daniel Grigorie ◽  
Alina Şucaliuc ◽  
Ramona M. Drăguţ ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Vitamin D ◽  
Bone Turnover ◽  
Newly Diagnosed ◽  
Markers Of Bone Turnover ◽  
25 Hydroxy Vitamin D

scholarly journals Inverse Association of Plasma Vanadium Levels with Newly Diagnosed Type 2 Diabetes in a Chinese Population

2014 ◽  
Vol 180 (4) ◽  
pp. 378-384 ◽  
Author(s):  
X. Wang ◽  
T. Sun ◽  
J. Liu ◽  
Z. Shan ◽  
Y. Jin ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Chinese Population ◽  
Inverse Association ◽  
Newly Diagnosed

Metabolic flexibility, insulin sensitivity and genetic variations in newly diagnosed patients with type 2 diabetes

2015 ◽  
Vol 10 (S 01) ◽  
Author(s):  
M Apostolopoulou ◽  
K Strassburger ◽  
B Knebel ◽  
J Kotzka ◽  
J Szendroedi ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Insulin Sensitivity ◽  
Genetic Variations ◽  
Metabolic Flexibility ◽  
Newly Diagnosed
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