608-P: High er Level of Angiopoietin-Like Protein-2 Is Associated with Diabetic Macular Edema in Patients with Type 2 Diabetes Mellitus

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 608-P
Author(s):  
NING ZHANG ◽  
YAXIN AN ◽  
RUILI YIN ◽  
DONG ZHAO
2016 ◽  
Vol 32 (5) ◽  
pp. 651-654 ◽  
Author(s):  
Mehmet Tetikoğlu ◽  
Serdar Aktas ◽  
Hacı Murat Sagdık ◽  
Sıla Tasdemir Yigitoglu ◽  
Fatih Özcura

2018 ◽  
Vol 16 (2) ◽  
pp. 11-19
Author(s):  
Daniel Paniagua Herrera ◽  
Consuelo González Salinas

Objective:To determine the prevalence of diabetic retinopathy and diabetic macular edema by means of retinography in patients diagnosed with Type 2 diabetes mellitus according to time of evolution and degree of vision loss with and without refractive correction.Method: A descriptive cross-sectional study of 150 patients with Type 2 diabetes mellitus assessed in optometry in various health centers from the Sanitary Jurisdiction of Tlalpan, Health Services of Mexico City.Results: 150 patients (70% women, 30% men) aged 60 (+/– 7.77) were diagnosed with Type 2 diabetes mellitus, 52% of them with an evolution of 12.09 years (+/– 3.48). Of the total number of patients, 72.33% had retinopathy and/or diabetic macular edema lesions. The average visual acuity improved from 0.62 (+/– 0.48) to 0.37 (+/– 0.38) with refractive correction, absolute disability decreased by –18.76% and null or slight disability increased by 31.31%. Of the total population, 75.5% remained under monitoring in primary care, and 24.5% were referred to tertiary care in ophthalmology.Conclusion: The strategic opportunity to combat vision loss due to retinopathy and diabetic macular edema is found in its timely detection by health personnel trained in scrutiny and control at the primary care level, which would represent a decreased hospital load in tertiary care, thereby reducing costs for the health systems, as well as cost-efficiency for the years of sight gained and optimization of the patient’s global vision.


2019 ◽  
Vol 16 (2) ◽  
pp. 225-229
Author(s):  
M. V. Pshenichnov ◽  
O. V. Kolenko ◽  
E. L. Sorokin ◽  
Ya. E. Pashentcev

Purpose. Revealing of the ocular risk factors in the formation of diabetic macular edema (ME) in type 2 diabetes mellitus (DM2).Patients and methods. A 3.5-year research of 80 patients (160 eyes) with DM2 without signs of ME at the beginning of the research was performed. The main group consisted of 46 patients with ME symptoms on one or both eyes during the research period, the comparison group included 34 patients without ME symptoms to the end of the research. The initial ocular characteristics were retrospect compared in groups.Results. The mean value of the axial lengths (AL) in the eyes of the main group was 23.12 ± 0.75 mm compared to 23.82 ± 0.62 mm in the comparison group (significant difference, p < 0.01). AL was less than 23.5 mm in 66 % of the eyes in the main group and only in 22 % of the eyes in the comparison group (p < 0.01). The mean value of the initial macular retina volume in the main group was significantly higher than in the comparison group — 7.51 ± 0.22 mm3 and 7.21 ± 0.12 mm3, respectively (p < 0.01). Initial background diabetic retinopathy (DR) was noted in 73 % of the eyes in the main group, which significantly differed from the comparison group, where this index was noted only in 13 % of the eyes (p < 0.01).Conclusion. Significant ocular risk factors for the formation of ME in patients with DM2 are: the initial macular retina volume more than 7.3 mm3, the value of the AL less than 23.5 mm; the initial background DR. The use of the detected morphometric parameters of eye and retina in combination with an adequate assessment of the risk factors in human organism makes it possible to assume with high degree of probability a high risk of the primary formation of diabetic ME in patients with DM2. 


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