1013-P: Effect of Upper Gastrointestinal Disease on the Pharmacokinetics of Oral Semaglutide in Subjects with Type 2 Diabetes

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 1013-P ◽  
Author(s):  
JURIS J. MEIER ◽  
CHARLOTTE GRANHALL ◽  
ULRIKE HOEVELMANN ◽  
ANDREA NAVARRIA ◽  
LEONA PLUM-MOERSCHEL ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Gastrointestinal Disease ◽  
Upper Gastrointestinal

scholarly journals Effect of upper gastrointestinal disease on the pharmacokinetics of oral semaglutide in subjects with type 2 diabetes

2021 ◽  
Author(s):  
Juris J. Meier ◽  
Charlotte Granhall ◽  
Ulrike Hoevelmann ◽  
Andrea Navarria ◽  
Leona Plum‐Moerschel ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Gastrointestinal Disease ◽  
Upper Gastrointestinal

scholarly journals Efficacy of Prokinetic Itopride in Type 2 Diabetes Mellitus

2020 ◽  
pp. 35-39
Author(s):  
A. E. Shklyaev ◽  
D. D. Kazarin ◽  
Y. V. Gorbunov
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Gastrointestinal Tract ◽  
Chronic Gastritis ◽  
Motor Dysfunction ◽  
Upper Gastrointestinal Tract ◽  
Itopride Hydrochloride ◽  
Upper Gastrointestinal

The constant increase in the incidence of diabetes in the world and the high frequency of lesions of the upper gastrointestinal tract with impaired motor function in this category of patients, on the one hand, worsen the clinical picture, and on the other, reduce the effectiveness of sugar-lowering therapy. Currently, specialists have at their disposal a number of prokinetics that contribute to the restoration of the motor-evacuation function of the stomach, but many of them have many undesirable effects. The aim of our study was to evaluate the effectiveness of itopride hydrochloride in the treatment of patients with chronic gastritis associated with Helicobacter pylori and type 2 diabetes. During the study, both general clinical and more specific research methods were used, in particular, esophagogastroduodenoscopy. According to the results of the study, the use of prokinetics in the treatment of patients with type 2 diabetes mellitus reduces the manifestations of impaired motor-evacuation function of the upper gastrointestinal tract. The results obtained indicate to verify the manifestations of chronic gastritis in patients with type 2 diabetes mellitus and the identification of motor dysfunction and the need for prokinetic therapy.

Expression of taste molecules in the upper gastrointestinal tract in humans with and without type 2 diabetes

Gut ◽  
2008 ◽  
Vol 58 (3) ◽  
pp. 337-346 ◽  
Author(s):  
R L Young ◽  
K Sutherland ◽  
N Pezos ◽  
S M Brierley ◽  
M Horowitz ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Gastrointestinal Tract ◽  
Upper Gastrointestinal Tract ◽  
Upper Gastrointestinal
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