Independent Association of a Metabolic Syndrome Severity Score with All-Cause Mortality in Type 1 Diabetes—A 10-Year Follow-Up

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 618-P
Author(s):  
GIUSEPPE PENNO ◽  
MONIA GAROFOLO ◽  
ROSA GIANNARELLI ◽  
FABRIZIO CAMPI ◽  
DANIELA LUCCHESI ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Type 1 Diabetes ◽  
Severity Score ◽  
All Cause Mortality ◽  
Independent Association

Estimated Glucose Disposal Rate as a Predictor of All-Cause Mortality in Type 1 Diabetes—A 10-Year Follow-Up Study

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 1694-P
Author(s):  
MONIA GAROFOLO ◽  
ALESSANDRA BERTOLOTTO ◽  
FABRIZIO CAMPI ◽  
DANIELA LUCCHESI ◽  
LAURA GIUSTI ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Glucose Disposal ◽  
Follow Up Study ◽  
All Cause Mortality ◽  
Estimated Glucose Disposal Rate ◽  
Glucose Disposal Rate

453-P: Metabolic Syndrome Severity Score, All-Cause Mortality, and Incident Vascular Events in Type 2 Diabetes: A 13-Year, Single-Centre, Follow-Up Study

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 453-P
Author(s):  
MONIA GAROFOLO ◽  
ELISA GUALDANI ◽  
DANIELA LUCCHESI ◽  
LAURA GIUSTI ◽  
VERONICA SANCHO-BORNEZ ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Metabolic Syndrome ◽  
Severity Score ◽  
Single Centre ◽  
Vascular Events ◽  
Follow Up Study ◽  
All Cause Mortality

scholarly journals Comment on Garofolo et al. Insulin Resistance and Risk of Major Vascular Events and All-Cause Mortality in Type 1 Diabetes: A 10-Year Follow-up Study. Diabetes Care 2020;43:e139–e141

Diabetes Care ◽  
2021 ◽  
Vol 44 (4) ◽  
pp. e79-e80
Author(s):  
José-Miguel González-Clemente ◽  
Gemma Llauradó ◽  
Lara Albert ◽  
Olga Giménez-Palop ◽  
Eugenia Berlanga ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Type 1 Diabetes ◽  
Diabetes Care ◽  
Vascular Events ◽  
Follow Up Study ◽  
All Cause Mortality

Microvascular Disease Burden and All-Cause Mortality in Type 1 Diabetes-A 10-Year Follow-Up Study

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 1572-P
Author(s):  
MONIA GAROFOLO ◽  
ROSA GIANNARELLI ◽  
MICHELE ARAGONA ◽  
DANIELA LUCCHESI ◽  
LAURA GIUSTI ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Disease Burden ◽  
Microvascular Disease ◽  
Follow Up Study ◽  
All Cause Mortality

Sex differences in the association between myocardial function and prognosis in type 1 diabetes without known heart disease: the Thousand & 1 Study

2020 ◽  
Author(s):  
Mats Christian Højbjerg Lassen ◽  
Tor Biering-Sørensen ◽  
Peter Godsk Jørgensen ◽  
Henrik Ullits Andersen ◽  
Peter Rossing ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Heart Disease ◽  
Myocardial Function ◽  
Statistical Significance ◽  
Global Longitudinal Strain ◽  
Major Adverse Cardiovascular Events ◽  
All Cause Mortality ◽  
Males And Females

Abstract Aims In type 1 diabetes mellitus (T1DM), recent findings suggest that women have a greater excess risk of cardiovascular diseases (CVDs) compared to men. Impaired diastolic function is a common feature in T1DM. We investigated the association between myocardial function by echocardiography and outcomes in T1DM males and females without known heart disease. Methods and results A prospective cohort of individuals with T1DM without known heart disease from the outpatient clinic of Steno Diabetes Center Copenhagen. Follow-up was performed through Danish national registers. Outcomes, major adverse cardiovascular events (MACE) and all-cause mortality, were investigated. A total of 1079 participants (mean age: 49.6 ± 14.5 years, 52.6% male, mean duration of diabetes 25.8 ± 14.6 years) were included in the study. During follow-up (median 6.3 years, interquartile range 5.7–6.9), 142 (13.2%) experienced MACE and 63 (5.8%) died. Gender modified the relationship between E/e′ and both MACE and all-cause mortality (P = 0.016 and 0.007, respectively). In females, after multivariable adjustment, both E/e′ and global longitudinal strain (GLS) were significantly associated with MACE [E/e′: hazard ratio (HR) 1.15 confidence interval (CI) 95%: 1.07–1.24, per 1unit increase; and GLS: HR 1.19 CI 95%: 1.04–1.35, per 1% decrease] and with all-cause mortality (E/e′: HR 1.26 CI 95%: 1.11–1.44; and GLS: HR 1.27 CI 95%: 1.03–1.56). In males, the association between E/e′ and GLS and outcomes did not reach statistical significance. Conclusion In female individuals with T1DM both E/e′ and GLS provided independent prognostic information, whereas the associations were not significant in males. These results suggest that T1DM affects myocardial function differently in males and females, which may be related to the observed sex difference in CVD risk in T1DM.

scholarly journals Increased All-Cause Mortality in Patients With Type 1 Diabetes and High-Expression Mannan-Binding Lectin Genotypes: A 12-Year Follow-up Study

Diabetes Care ◽  
2015 ◽  
Vol 38 (10) ◽  
pp. 1898-1903 ◽  
Author(s):  
Jakob A. Østergaard ◽  
Steffen Thiel ◽  
Maria Lajer ◽  
Rudi Steffensen ◽  
Hans-Henrik Parving ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
High Expression ◽  
Follow Up Study ◽  
All Cause Mortality ◽  
Mannan Binding Lectin ◽  
Binding Lectin
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