Sex Differences in Neuropathy and Neuropathic Pain in Long-Standing Diabetes—Results from the Canadian Study of Longevity in Type 1 Diabetes

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 560-P
Author(s):  
NANCY CARDINEZ ◽  
LEIF ERIK LOVBLOM ◽  
JOHNNY-WEI BAI ◽  
ALON ABRAHAM ◽  
EVAN J. LEWIS ◽  
...  
2018 ◽  
Vol 32 (7) ◽  
pp. 660-664 ◽  
Author(s):  
Nancy Cardinez ◽  
Leif E. Lovblom ◽  
Johnny-Wei Bai ◽  
Evan Lewis ◽  
Alon Abraham ◽  
...  

2019 ◽  
Vol 33 (12) ◽  
pp. 107397 ◽  
Author(s):  
Nancy Cardinez ◽  
Leif E. Lovblom ◽  
Andrej Orszag ◽  
Vera Bril ◽  
David Z. Cherney ◽  
...  

2017 ◽  
Vol 41 (5) ◽  
pp. S62
Author(s):  
Nancy Cardinez ◽  
Leif E. Lovblom ◽  
Alon Abraham ◽  
Johnny Wei Bai ◽  
Daniel Scarr ◽  
...  

BMJ ◽  
2018 ◽  
pp. k4247 ◽  
Author(s):  
Elizabeth R C Millett ◽  
Sanne A E Peters ◽  
Mark Woodward

AbstractObjectivesTo investigate sex differences in risk factors for incident myocardial infarction (MI) and whether they vary with age.DesignProspective population based study.SettingUK Biobank.Participants471 998 participants (56% women; mean age 56.2) with no history of cardiovascular disease.Main outcome measureIncident (fatal and non-fatal) MI.Results5081 participants (1463 (28.8%) of whom were women) had MI over seven years’ mean follow-up, resulting in an incidence per 10 000 person years of 7.76 (95% confidence interval 7.37 to 8.16) for women and 24.35 (23.57 to 25.16) for men. Higher blood pressure indices, smoking intensity, body mass index, and the presence of diabetes were associated with an increased risk of MI in men and women, but associations were attenuated with age. In women, systolic blood pressure and hypertension, smoking status and intensity, and diabetes were associated with higher hazard ratios for MI compared with men: ratio of hazard ratios 1.09 (95% confidence interval 1.02 to 1.16) for systolic blood pressure, 1.55 (1.32 to 1.83) for current smoking, 2.91 (1.56 to 5.45) for type 1 diabetes, and 1.47 (1.16 to 1.87) for type 2 diabetes. There was no evidence that any of these ratios of hazard ratios decreased with age (P>0.2). With the exception of type 1 diabetes, the incidence of MI was higher in men than in women for all risk factors.ConclusionsAlthough the incidence of MI was higher in men than in women, several risk factors were more strongly associated with MI in women compared with men. Sex specific associations between risk factors and MI declined with age, but, where it occurred, the higher relative risk in women remained. As the population ages and the prevalence of lifestyle associated risk factors increase, the incidence of MI in women will likely become more similar to that in men.


Diabetes ◽  
2021 ◽  
Vol 70 (Supplement 1) ◽  
pp. 1120-P
Author(s):  
MARY ELIZABETH L. LEIGH ◽  
PAOLA GILSANZ ◽  
CHRIS MORAN ◽  
ANDREW J. KARTER ◽  
RACHEL A. WHITMER

Diabetes Care ◽  
2018 ◽  
Vol 42 (2) ◽  
pp. 273-280 ◽  
Author(s):  
Julie A. Lovshin ◽  
Yuliya Lytvyn ◽  
Leif E. Lovblom ◽  
Alexandra Katz ◽  
Geneviève Boulet ◽  
...  

PLoS ONE ◽  
2018 ◽  
Vol 13 (4) ◽  
pp. e0196647 ◽  
Author(s):  
Daniel Scarr ◽  
Leif E. Lovblom ◽  
Nancy Cardinez ◽  
Andrej Orszag ◽  
Mohammed A. Farooqi ◽  
...  

Diabetes Care ◽  
2018 ◽  
Vol 41 (12) ◽  
pp. 2570-2578 ◽  
Author(s):  
Julie A. Lovshin ◽  
Petter Bjornstad ◽  
Leif E. Lovblom ◽  
Johnny-Wei Bai ◽  
Yuliya Lytvyn ◽  
...  

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