Diabetes Mellitus and High Triglycerides Are Significant Predictors of Major Cardiovascular Events and Increased Health Care Costs and Resource Utilization—A Real-World Analysis of High-Risk Statin-Treated Patients

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 416-P
Author(s):  
PETER P. TOTH ◽  
CRAIG B. GRANOWITZ ◽  
MICHAEL HULL ◽  
SEPHY PHILIP
Author(s):  
Zhenxiang Zhao ◽  
Xiaomei Peng ◽  
Doug Faries ◽  
Carol Gaich ◽  
Patrick McCollam ◽  
...  

Objective: Diabetes is an independent prognostic factor for increased risk for ischemic heart disease. This study evaluates differences in resource utilization and health care costs for acute coronary syndrome (ACS) patients with and without diabetes mellitus (DM). Methods: A retrospective cohort study was conducted using a large US administrative claims database. Patients, ≥65, hospitalized with a primary diagnosis of ACS between 01/01/2007 and 12/31/2007 were identified and categorized into 2 groups: 1) with DM (ACS patients had ≥ 2 outpatient office visits or 1 hospitalization with the DM diagnosis during the 1 year before/within the index hospitalization) and 2) without DM. Patients with complete insurance coverage 1-year pre- and post- index hospitalization were included. Annual health care costs and resource utilization were compared usingChi-square tests for categorical variables and Wilcoxon rank-sum tests for continuous variables (all p<.05 unless otherwise stated). Results: Of 5,840 identified patients, 1,609 (28%) were diabetic and 4,231 (72%) were non-diabetic. A higher percentage of diabetic patients had at least one all-cause rehospitalization event (44.4% vs. 35.7%) or CV-related rehospitalization event (27.0% vs. 19.5%). Mean length of stay (LOS) was longer for DM patients during the index hospitalization (6.3 days vs. 5.5 days), as well as during the CV-related rehospitalization (5.7 days vs. 4.8 days). In addition, patients with DM had more physician's office visits (18.3 vs. 15.0), ER visits (0.6 vs. 0.5), and outpatient hospital visits (7.4 vs. 6.1) during the 12-month follow-up period. Both cohorts had similar index ACS hospitalization costs ($18,532 vs. $17,609) but DM patients incurred higher rehospitalization costs (all-cause: $21,064 vs. $13,821; CV-related: $11,086 vs. $7,260), outpatient costs (all-cause: $28,167 vs. $19,815; CV-related: $7,193 vs. $5,686), and pharmacy costs (all-cause: $5,537 vs. $3,815; CV-related: $3,522 vs. $3,143). One-year follow-up health care costs were significantly higher for patients with DM compared with those without DM ($54,768 vs. $37,451). Conclusion: The presence of DM is significantly associated with greater resource utilization and health care costs for ACS patients.


2016 ◽  
Vol 12 (4) ◽  
pp. 307-311 ◽  
Author(s):  
Bruna Camilo Turi ◽  
Henrique Luiz Monteiro ◽  
Rômulo Araújo Fernandes ◽  
Jamile Sanches Codogno

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