Liraglutide-Based Therapy Shows More Prominent Effect than Conventional Insulin Therapy to Achieve HbA1c Target, Especially in Patients with Short Duration

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 2297-PUB
Author(s):  
KOJI KASHIMA ◽  
HIROYUKI SHIMIZU ◽  
MASANOBU YAMADA
Keyword(s):  
Insulin Therapy ◽  
Short Duration ◽  
Conventional Insulin Therapy ◽  
Hba1c Target

Observations on Control of Glycemia with Conventional Insulin Therapy or Continuous Subcutaneous Insulin Infusion

Diabetes ◽  
1985 ◽  
Vol 34 (Supplement_3) ◽  
pp. 22-26 ◽  
Author(s):  
W. V. Tamborlane ◽  
M. C. Champion ◽  
R. A. Rizza ◽  
F. J. Service ◽  
R. M. Bergenstal ◽  
...  
Keyword(s):  
Insulin Therapy ◽  
Continuous Subcutaneous Insulin Infusion ◽  
Insulin Infusion ◽  
Subcutaneous Insulin ◽  
Conventional Insulin Therapy

scholarly journals Model-Based Tool for Personalized Adjustment of Basal Insulin Supply in Patients With Intensified Conventional Insulin Therapy

2019 ◽  
Vol 13 (5) ◽  
pp. 928-934
Author(s):  
Lutz Vogt ◽  
Andreas Thomas ◽  
Gert Fritzsche ◽  
Peter Heinke ◽  
Klaus-Dieter Kohnert ◽  
...  
Keyword(s):  
Insulin Therapy ◽  
Basal Insulin ◽  
Insulin Pump ◽  
Insulin Pump Therapy ◽  
Insulin Dosage ◽  
Treatment Team ◽  
Pump Therapy ◽  
Modeling Tool ◽  
Conventional Insulin Therapy ◽  
Model Based

Background: The decisive factor in successful intensive insulin therapy is the ability to deliver need-based-adjusted nutrition-independent insulin dosages at the closest possible approximation to the physiological insulin level. Because this basal insulin requirement is strongly influenced by the patient’s lifestyle, its subtlety is of great importance. This challenge is very different between patients with type 1 diabetes and those with insulin-dependent type 2 diabetes. Furthermore, it is more difficult to finetune a basal insulin dosage with intensified conventional insulin therapy (ICT), due to delayed insulin delivery, compared to insulin pump therapy, which provides continuous delivery of small doses of exclusively short-acting insulin. In all cases, the goal is to achieve an optimal basal delivery rate. Method: We hypothesized that this goal could be achieved with a modeling tool that determined the optimal basal insulin supply based on the patient’s anamnestic data and monitored glucose values. This type of modeling tool has been used in health insurance programs in Germany to improve insulin control in patients that receive ICT. Results: Our retrospective data analysis showed that this modeling tool provided a significant improvement in metabolic control, significant reductions in HbA1c and Q scores, and improved time-in-range values, with reduced daily insulin levels. Conclusion: The model-based basal rate test could provide additional data of the actual effect of the basal insulin adjustment in intensified insulin treated diabetes to the physician or treatment team.

Intensive Conventional Insulin Therapy for Type II Diabetes: Metabolic effects during a 6-mo outpatient trial

Diabetes Care ◽  
1993 ◽  
Vol 16 (1) ◽  
pp. 21-31 ◽  
Author(s):  
R. R. Henry ◽  
B. Gumbiner ◽  
T. Ditzler ◽  
P. Wallace ◽  
R. Lyon ◽  
...  
Keyword(s):  
Insulin Therapy ◽  
Type Ii Diabetes ◽  
Metabolic Effects ◽  
Type Ii ◽  
Conventional Insulin Therapy

Long-term adherence to intensified conventional insulin therapy

2009 ◽  
Vol 103 (04) ◽  
pp. 256-259 ◽  
Author(s):  
K. Schmidt ◽  
B. O. Boehm ◽  
E. Schifferdecker ◽  
K. H. Usadel
Keyword(s):  
Insulin Therapy ◽  
Conventional Insulin Therapy
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