scholarly journals Cardiac Autonomic Function Is Associated With Myocardial Flow Reserve in Type 1 Diabetes

Diabetes ◽  
2019 ◽  
Vol 68 (6) ◽  
pp. 1277-1286 ◽  
Author(s):  
Emilie H. Zobel ◽  
Philip Hasbak ◽  
Signe A. Winther ◽  
Christian Stevns Hansen ◽  
Jesper Fleischer ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Autonomic Function ◽  
Myocardial Flow Reserve ◽  
Cardiac Autonomic Function ◽  
Flow Reserve ◽  
Myocardial Flow

A3993 Myocardial flow reserve assessed by Cardiac 82Rb PET/CT is associated with albumin excretion in patients with type 1 diabetes

2018 ◽  
Vol 36 ◽  
pp. e147
Author(s):  
Tine Hansen ◽  
Emilie H. Zobel ◽  
Signe A. Winther ◽  
Philip Hasbak ◽  
Bernt J. von Scholten J. von Scholten ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Myocardial Flow Reserve ◽  
Albumin Excretion ◽  
Flow Reserve ◽  
Pet Ct ◽  
Myocardial Flow

scholarly journals Eighteen Years of Fair Glycemic Control Preserves Cardiac Autonomic Function in Type 1 Diabetes

Diabetes Care ◽  
2004 ◽  
Vol 27 (4) ◽  
pp. 963-966 ◽  
Author(s):  
J. R. Larsen ◽  
H. Sjoholm ◽  
T. J. Berg ◽  
L. Sandvik ◽  
M. Brekke ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Glycemic Control ◽  
Autonomic Function ◽  
Cardiac Autonomic Function

scholarly journals Asymptomatic ST-depression during exercise testing in children and adolescents with type 1 diabetes mellitus and autonomic dysfunction

2015 ◽  
Vol 18 (2) ◽  
pp. 54-60
Author(s):  
Dmitry Nikitich Laptev ◽  
Tamara Leonidovna Kuraeva ◽  
Galina Vladimirovna Ryabykina ◽  
Sergey Dmitrievich Polyakov ◽  
Irina Timofeevna Korneeva ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Children And Adolescents ◽  
Autonomic Function ◽  
Cardiac Autonomic Function ◽  
Post Exercise ◽  
St Segment ◽  
Cardiovascular Morbidity And Mortality

Aim. The aim of this study was to investigate cardiac autonomic function as assessed by ST dynamics during and post-exercise in children and adolescents with type 1 diabetes mellitus (T1DM). Materials and methods. The study included 71 young patients with T1DM. The patients were aged 9?18 years and had no history of macrovascular disease or renal disease, including microalbuminuria. Cardiac autonomic function was assessed using cardiovascular tests and 24-h ECG monitoring with automatic calculation of QT interval and heart rate variability parameters. Each patient underwent the physical working capacity 170 test. Results. The prevalence of cardiovascular autonomic neuropathy (CAN) was 30.9%. The frequency of asymptomatic ST-segment depression increased during exercise in 10 (45.5%) patients with CAN (CAN+) compared with 9 (18.4%) patients without CAN (CAN-; p=0.042). During the recovery period, asymptomatic ST-segment depression was present in the first minute in 8 (36.4%) CAN+ patients compared with 1 (2%) CAN- patient (p=0.0003) and in the second minute in 5 (22.7%) CAN+ patients compared with 1 (2%) CAN- patient (p=0.0095). Conclusion. Children and adolescents with T1DM and impaired autonomic function have increased prevalence of asymptomatic ST-segment depression during and post-exercise. The presence of cardiovascular risk factors in children and adolescents with T1DM and CAN may contribute to the increased cardiovascular morbidity and mortality during adulthood in patients with T1DM.

scholarly journals Cardiac Autonomic Function Correlates with Arterial Stiffness in the Early Stage of Type 1 Diabetes

2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
S. Liatis ◽  
K. Alexiadou ◽  
A. Tsiakou ◽  
K. Makrilakis ◽  
N. Katsilambros ◽  
...  
Keyword(s):  
Heart Rate ◽  
Type 1 Diabetes ◽  
Arterial Stiffness ◽  
Autonomic Function ◽  
Multivariable Analysis ◽  
Cardiac Autonomic Neuropathy ◽  
Rate Variation ◽  
Large Artery ◽  
Cardiac Autonomic Function

Arterial stiffness is increased in type 1 diabetes (T1D), before any clinical complications of the disease are evident. The aim of the present paper was to investigate the association between cardiac autonomic function and arterial stiffness in a cohort of young T1D patients, without history of hypertension and any evidence of macrovascular and/or renal disease. Large artery stiffness was assessed by measurement of carotid-femoral pulse wave velocity (PWV). Cardiac autonomic function was assessed by the cardiovascular tests proposed by Ewing and Clarke. Patients with a high cardiac autonomic neuropathy score (4) had significantly higher PWV than those with a low score (0-1). A negative, heart rate-independent, correlation between PWV and heart rate variation during respiration was observed (). In multivariable analysis, index was the strongest correlate of PWV (β-coefficient = −0.326, ). Cardiac parasympathetic function is a strong predictor of large arterial stiffness, in young T1D patients free of macrovascular and renal complications.

scholarly journals Аrterial stiffness and cardiovascular autonomic neuropathy relationship in children and adolescents with type 1 diabetes mellitus

2015 ◽  
Vol 18 (1) ◽  
pp. 94-100 ◽  
Author(s):  
Dmitriy Nikitich Laptev
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Arterial Stiffness ◽  
Children And Adolescents ◽  
Qt Interval ◽  
Autonomic Function ◽  
Independent Predictor ◽  
Cardiac Autonomic Function ◽  
Cardiovascular Tests

Aim. To evolve the association between cardiac autonomic function and arterial stiffness in children and adolescents with type 1 diabetes mellitus (T1DM). Materials and methods. 72 T1DM patients aged 7?18 years without history of macrovascular complications or renal disease, including microalbuminuria, were involved in the study. Cardiac function was assessed by the cardiovascular tests and 24-hour ECG monitoring with automatic calculation of QT interval and heart rate variability (HRV) parameters. Artery stiffness was assessed by measurement of pulse wave velocity (PWV) and augmentation index (AI) obtained from arterial blood pressure monitoring for 24 hours. Results. Estimated prevalence of cardiovascular autonomic neuropathy (CAN) was 31,9%. CAN+ patients had significantly higher PWV and AI than those without CAN. A negative correlation between PWV and AI with some cardiovascular tests and HRV parameters was observed. In multivariable analysis, AI was independent predictor of autonomic dysfunction defined as number of positive cardiovascular tests, HRV parameters below normal values and prolongation of QT interval (?. =0,18; p=0,035). Conclusion. Cardiac autonomic function is an independent predictor of arterial stiffness, in children and adolescents with T1D without macrovascular and renal complications. The presence of cardiovascular risk factors and arterial stiffness in children and adolescents with T1DM may contribute to the increased cardiovascular morbidity and mortality in adulthood in patients with CAN.

Cardiac autonomic function in children with type 1 diabetes

2018 ◽  
Vol 177 (6) ◽  
pp. 805-813 ◽  
Author(s):  
Kotb Abbass Metwalley ◽  
Sherifa Ahmed Hamed ◽  
Hekma Saad Farghaly
Keyword(s):  
Type 1 Diabetes ◽  
Autonomic Function ◽  
Cardiac Autonomic Function
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