scholarly journals Human Insulinomas Show Distinct Patterns of Insulin Secretion In Vitro

Diabetes ◽  
2015 ◽  
Vol 64 (10) ◽  
pp. 3543-3553 ◽  
Author(s):  
Jean-Claude Henquin ◽  
Myriam Nenquin ◽  
Yves Guiot ◽  
Jacques Rahier ◽  
Christine Sempoux
Keyword(s):  
Insulin Secretion ◽  
Insulin Secretion In Vitro

EFFECT OF EXOGENOUS ZINC ON INSULIN SECRETION IN. VITRO

Endocrinology ◽  
1981 ◽  
Vol 108 (2) ◽  
pp. 730-732 ◽  
Author(s):  
DIANNE P. FIGLEWICZ ◽  
ANNELIESE HELDT ◽  
SARA E. FORHAN ◽  
GEROLD M. GRODSKY
Keyword(s):  
Insulin Secretion ◽  
Insulin Secretion In Vitro

Synthesis of amide compounds of ferulic acid, and their stimulatory effects on insulin secretion in vitro

2003 ◽  
Vol 11 (17) ◽  
pp. 3807-3813 ◽  
Author(s):  
Eisaku Nomura ◽  
Ayumi Kashiwada ◽  
Asao Hosoda ◽  
Kozo Nakamura ◽  
Hideko Morishita ◽  
...  
Keyword(s):  
Insulin Secretion ◽  
Ferulic Acid ◽  
Insulin Secretion In Vitro

scholarly journals A possible role of plasma glutathione in glucose-mediated insulin secretion: in vitro and in vivo studies in rats

Diabetologia ◽  
1989 ◽  
Vol 32 (11) ◽  
Author(s):  
H.P.T. Ammon ◽  
S. Klumpp ◽  
A. Fu� ◽  
E.J. Verspohl ◽  
H. Jaeschke ◽  
...  
Keyword(s):  
Insulin Secretion ◽  
In Vivo Studies ◽  
Plasma Glutathione ◽  
Insulin Secretion In Vitro

Hyperglycemic athymic nude mice: factors affecting in vitro insulin secretion

1992 ◽  
Vol 263 (6) ◽  
pp. E1131-E1133
Author(s):  
A. Zeidler ◽  
P. Edwards ◽  
J. Goldman ◽  
S. Kort ◽  
W. P. Meehan ◽  
...  
Keyword(s):  
Animal Model ◽  
Insulin Secretion ◽  
Insulin Dependent Diabetes Mellitus ◽  
Dependent Diabetes Mellitus ◽  
Factors Affecting ◽  
In Vitro Insulin Secretion ◽  
Insulin Secretion In Vitro ◽  
And Control

The strain of athymic nude male mice (ANM) developed at the University of Southern California (USC) exhibits spontaneous hyperglycemia and relative hypoinsulinemia in vivo. To investigate factors that influence insulin secretion in this animal model of non-insulin-dependent diabetes mellitus, we utilized the isolated perfused mouse pancreas of the ANM-USC and control BALB/c mice. We compared in vitro glucose-induced insulin secretion in ANM-USC and control mice, inhibition of secretion by somatostatin, and variability of insulin secretion over the two-year period it took to complete these experiments. Glucose-induced insulin secretion from the isolated pancreas was biphasic in both ANM-USC and controls. Insulin secretion was quantitatively equal to or greater than control mice, depending on the phase of secretion analyzed and the source of the control mice. In contrast to pancreases of control mice, insulin secretion from ANM-USC pancreases was relatively resistant to inhibition of insulin secretion by somatostatin. Variability in insulin secretion over the two years in which these experiments were performed was greater from pancreases of control than that observed from pancreases of the ANM-USC. The hyperglycemic ANM-USC mouse does not demonstrate diminished insulin secretion in vitro yet is relatively hypoinsulinemic in vivo. Thus circulating factors other than somatostatin might contribute to the insulinopenic stage in this animal model.

scholarly journals Suppression of Sulfonylurea- and Glucose-Induced Insulin Secretion In Vitro and In Vivo in Mice Lacking the Chloride Transport Protein ClC-3

2009 ◽  
Vol 10 (4) ◽  
pp. 309-315 ◽  
Author(s):  
Dai-Qing Li ◽  
Xingjun Jing ◽  
Albert Salehi ◽  
Stephan C. Collins ◽  
Michael B. Hoppa ◽  
...  
Keyword(s):  
Insulin Secretion ◽  
Chloride Transport ◽  
Transport Protein ◽  
Insulin Secretion In Vitro

Antidiabetic activity ofCroton klozchianusin rats and direct stimulation of insulin secretion in-vitro

2008 ◽  
Vol 60 (3) ◽  
pp. 371-376 ◽  
Author(s):  
R. Govindarajan ◽  
M. Vijayakumar ◽  
Ch. V. Rao ◽  
P. Pushpangadan ◽  
Henry Asare-Anane ◽  
...  
Keyword(s):  
Insulin Secretion ◽  
Antidiabetic Activity ◽  
Direct Stimulation ◽  
Insulin Secretion In Vitro ◽  
Stimulation Of

Cinchonain Ib isolated from Eriobotrya japonica induces insulin secretion in vitro and in vivo

2009 ◽  
Vol 124 (2) ◽  
pp. 224-227 ◽  
Author(s):  
Fadi Qa’dan ◽  
Eugen. J. Verspohl ◽  
Adolf Nahrstedt ◽  
Frank Petereit ◽  
Khalid Z. Matalka
Keyword(s):  
Insulin Secretion ◽  
Eriobotrya Japonica ◽  
Insulin Secretion In Vitro

ASSESSMENT OF INSULIN SECRETION IN VITRO FROM MICROENCAPSULATED FETAL PORCINE ISLET-LIKE CELL CLUSTERS AND RAT, MOUSE, AND HUMAN PANCREATIC ISLETS1

1997 ◽  
Vol 63 (12) ◽  
pp. 1712-1718 ◽  
Author(s):  
Stellan Sandler ◽  
Arne Andersson ◽  
D??cio L. Eizirik ◽  
Claes Hellerstr??m ◽  
Terje Espevik ◽  
...  
Keyword(s):  
Insulin Secretion ◽  
Cell Clusters ◽  
Porcine Islet ◽  
Insulin Secretion In Vitro
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