scholarly journals PKA Enhances the Acute Insulin Response Leading to the Restoration of Glucose Control

Diabetes ◽  
2014 ◽  
Vol 64 (5) ◽  
pp. 1688-1697 ◽  
Author(s):  
Kelly A. Kaihara ◽  
Lorna M. Dickson ◽  
Johanne H. Ellenbroek ◽  
Caitlin M.D. Orr ◽  
Brian T. Layden ◽  
...  
Keyword(s):  
Glucose Control ◽  
Insulin Response ◽  
Acute Insulin Response

360-OR: BETA-2 Score Is Highly Correlated with Acute Insulin Response to Intravenous Glucose: An Analysis of the Clinical Islet Transplantation Consortium Trials

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 360-OR
Author(s):  
PETER A. SENIOR ◽  
MICHAEL R. RICKELS ◽  
THOMAS EGGERMAN ◽  
LEVENT BAYMAN ◽  
JULIE QIDWAI ◽  
...  
Keyword(s):  
Islet Transplantation ◽  
Insulin Response ◽  
Acute Insulin Response ◽  
Intravenous Glucose ◽  
Clinical Islet Transplantation ◽  
Beta 2 ◽  
Highly Correlated

Evidence for linkage between a region on chromosome 1p and the acute insulin response in Pima Indians

Diabetes ◽  
1995 ◽  
Vol 44 (4) ◽  
pp. 478-481 ◽  
Author(s):  
D. B. Thompson ◽  
R. C. Janssen ◽  
V. M. Ossowski ◽  
M. Prochazka ◽  
W. C. Knowler ◽  
...  
Keyword(s):  
Insulin Response ◽  
Pima Indians ◽  
Acute Insulin Response ◽  
Chromosome 1P

A Physical Map at 1p31 Encompassing the Acute Insulin Response Locus and the Leptin Receptor

Genomics ◽  
1997 ◽  
Vol 39 (2) ◽  
pp. 227-230 ◽  
Author(s):  
D.Bruce Thompson ◽  
Jeff Sutherland ◽  
Warren Apel ◽  
Victoria Ossowski
Keyword(s):  
Leptin Receptor ◽  
Physical Map ◽  
Insulin Response ◽  
Acute Insulin Response

Theophylline prevents the inhibitory effect of prostaglandin E 2 on glucose-induced insulin secretion in man

1988 ◽  
Vol 118 (2) ◽  
pp. 187-192 ◽  
Author(s):  
D. Giugliano ◽  
D. Cozzolino ◽  
T. Salvatore ◽  
R. Giunta ◽  
R. Torella
Keyword(s):  
Insulin Secretion ◽  
Inhibitory Action ◽  
Insulin Response ◽  
Inhibitory Effect ◽  
Prostaglandin E ◽  
Intracellular Camp ◽  
Adenylate Cyclase System ◽  
Loading Dose ◽  
Phosphodiesterase Activity ◽  
Acute Insulin Response

Abstract. This study was undertaken to assess the mechanism by which prostaglandins of the E series inhibit glucose-induced insulin secretion in man. Acute insulin response (mean change 3–10 min) to iv glucose (0.33 g/kg) was decreased by 40% during the infusion of prostaglandin E2 (10 μg/min) and glucose disappearance rates were reduced (P < 0.05). Insulin response to arginine (5 g iv) and tolbutamide (1 g iv) were not affected by the same rate of prostaglandin E2 infusion. The inhibitory effect of prostaglandin E2 on glucoseinduced insulin secretion was prevented by theophylline (100 mg as a loading dose followed by a 5 mg/min infusion), a drug that increases the intracellular cAMP concentrations by inhibiting phosphodiesterase activity. Our data suggest the involvement of the adenylate cyclase system in the inhibitory action of prostaglandin E2 on glucose-induced insulin secretion in man.

scholarly journals Acute Insulin Response and  -Cell Compensation in Normal Subjects Treated With Olanzapine or Risperidone for 2 Weeks: Response to Jindal

Diabetes Care ◽  
2007 ◽  
Vol 30 (7) ◽  
pp. e70-e70
Author(s):  
T. A. Hardy ◽  
A. L. Meyers ◽  
J. Yu ◽  
S. S. Shankar ◽  
H. O. Steinberg ◽  
...  
Keyword(s):  
Insulin Response ◽  
Normal Subjects ◽  
Acute Insulin Response

Acute Insulin Response Following Exercise and Relationship to Lipid Changes in Sedentary African-American Women

2004 ◽  
Vol 36 (Supplement) ◽  
pp. S19
Author(s):  
Kyle D. Biggerstaff ◽  
Scott J. Clark ◽  
Joshua S. Wooten ◽  
Sofiya Alhassan ◽  
Eric P. Plaisance ◽  
...  
Keyword(s):  
African American ◽  
African American Women ◽  
Insulin Response ◽  
Acute Insulin Response ◽  
American Women

scholarly journals Association of TCF7L2 Gene Polymorphisms with Reduced Acute Insulin Response in Hispanic Americans

2008 ◽  
Vol 93 (1) ◽  
pp. 304-309 ◽  
Author(s):  
Nicholette D. Palmer ◽  
Allison B. Lehtinen ◽  
Carl D. Langefeld ◽  
Joel K. Campbell ◽  
Steven M. Haffner ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Hispanic Americans ◽  
Insulin Response ◽  
Acute Insulin Response ◽  
Tcf7l2 Gene
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