scholarly journals In Vivo Imaging of Immuno-Spin Trapped Radicals With Molecular Magnetic Resonance Imaging in a Diabetic Mouse Model

Diabetes ◽  
2012 ◽  
Vol 61 (10) ◽  
pp. 2405-2413 ◽  
Author(s):  
R. A. Towner ◽  
N. Smith ◽  
D. Saunders ◽  
M. Henderson ◽  
K. Downum ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Mouse Model ◽  
In Vivo Imaging ◽  
Diabetic Mouse ◽  
Resonance Imaging

In Vivo Magnetic Resonance Imaging of Intravenously Injected Neural Stem Cells in a Mouse Model of Multiple Sclerosis

2006 ◽  
Vol 19 (5) ◽  
pp. 635-636
Author(s):  
L.S. Politi ◽  
S. Pluchino ◽  
M. Bacigaluppi ◽  
E. Brambilla ◽  
M. Cadioli ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Stem Cells ◽  
Magnetic Resonance ◽  
Mouse Model ◽  
Neural Stem Cells ◽  
Resonance Imaging

scholarly journals Cellular Magnetic Resonance Imaging: In Vivo Imaging of Melanoma Cells in Lymph Nodes of Mice

Neoplasia ◽  
2008 ◽  
Vol 10 (3) ◽  
pp. 207-216 ◽  
Author(s):  
Paula J Foster ◽  
Elizabeth A Dunn ◽  
Kristina E Karl ◽  
Jonatan A Snir ◽  
Colleen M Nycz ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Lymph Nodes ◽  
In Vivo Imaging ◽  
Melanoma Cells ◽  
Resonance Imaging

scholarly journals In Vivo Imaging of Tau Pathology Using Magnetic Resonance Imaging Textural Analysis

2017 ◽  
Vol 11 ◽  
Author(s):  
Niall Colgan ◽  
Balaji Ganeshan ◽  
Ian F. Harrison ◽  
Ozama Ismail ◽  
Holly E. Holmes ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
In Vivo Imaging ◽  
Textural Analysis ◽  
Resonance Imaging ◽  
Tau Pathology

Targeting Peritumoral Lesions Identified by Computed Tomography and Magnetic Resonance Imaging in Feline Injection-Site Sarcomas for Microscopic Examination

2021 ◽  
pp. 030098582110129
Author(s):  
Christiane V. Löhr ◽  
Susanne M. Stieger-Vanegas ◽  
Jesse L. Terry ◽  
Milan Milovancev ◽  
Jan Medlock
Keyword(s):  
Magnetic Resonance Imaging ◽  
Computed Tomography ◽  
Magnetic Resonance ◽  
Injection Site ◽  
Microscopic Examination ◽  
In Vivo Imaging ◽  
Surgical Margins ◽  
Surrounding Tissue ◽  
Resonance Imaging

Peritumoral lesions identified during in vivo imaging of feline injection-site sarcoma (FISS) are frequently interpreted as neoplastic. We recently showed that most peritumoral imaging-identified lesions (PTIILs) in FISS are non-neoplastic. In this article, we describe a protocol to target PTIIL for microscopic examination and report on the protocol’s performance. Ten client-owned cats with FISS were prospectively enrolled. A fiducial marker sutured onto the skin, centered on the palpable mass, served as reference point throughout the study. Each FISS and surrounding tissue was imaged in vivo by dual phase computed tomography angiography and multiple magnetic resonance imaging pulse sequences and each PTIIL documented. Subgross measurements obtained during trimming aided localization and identification of PTIIL during microscopy. Histologic findings were categorized by descending clinical relevance: neoplastic, equivocal, non-neoplastic, within normal limits (WNL). Based on in vivo imaging resolution limits, histologic findings were ≥3 mm in at least one dimension and ≥3 mm apart. Surgical margins served as control tissue for PTIILs. Eighty-one of 87 PTIIL were examined histologically; 13 were neoplastic, 16 equivocal, and 28 non-neoplastic; 24 had no identified histologic correlate. Two neoplastic and 10 equivocal findings were located outside of PTIILs but none of them were located in sections of surgical margins. Computation of a simple confusion matrix yielded fair sensitivity (70.4%) and low specificity (59.7%) for prediction of PTIIL by histologic findings. After combining instances of normal microanatomy with non-neoplastic histologic findings, specificity increased (85.1%) and sensitivity decreased (35.8%). The protocol is a blueprint for targeting PTIIL for microscopic examination but may benefit from further refinement.

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