scholarly journals Type 1 Diabetes Is Associated With Enterovirus Infection in Gut Mucosa

Diabetes ◽  
2012 ◽  
Vol 61 (3) ◽  
pp. 687-691 ◽  
Author(s):  
M. Oikarinen ◽  
S. Tauriainen ◽  
S. Oikarinen ◽  
T. Honkanen ◽  
P. Collin ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Enterovirus Infection ◽  
Gut Mucosa

scholarly journals Enterovirus Infection and Type 1 Diabetes: Closing in on a Link?: Figure 1

Diabetes ◽  
2015 ◽  
Vol 64 (5) ◽  
pp. 1503-1505 ◽  
Author(s):  
Teresa Rodriguez-Calvo ◽  
Matthias G. von Herrath
Keyword(s):  
Type 1 Diabetes ◽  
Enterovirus Infection

Simultaneous onset of Type 1 diabetes mellitus in identical infant twins with enterovirus infection

1998 ◽  
Vol 15 (6) ◽  
pp. 515-517 ◽  
Author(s):  
C.P. Smith ◽  
G.B. Clements ◽  
M.H. Riding ◽  
P. Collins ◽  
G.F. Bottazzo ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Enterovirus Infection

Recent enterovirus infection in type 1 diabetes: Evidence with a novel IgM method

2007 ◽  
Vol 79 (12) ◽  
pp. 1861-1867 ◽  
Author(s):  
A. Elfaitouri ◽  
A.-K. Berg ◽  
G. Frisk ◽  
H. Yin ◽  
T. Tuvemo ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Enterovirus Infection

scholarly journals Association Between Enterovirus Infection and Type 1 Diabetes Risk: A Meta-Analysis of 38 Case-Control Studies

2021 ◽  
Vol 12 ◽  
Author(s):  
Kan Wang ◽  
Fei Ye ◽  
Yong Chen ◽  
Jianxin Xu ◽  
Yufang Zhao ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Latin American ◽  
Meta Analysis ◽  
Pooled Analysis ◽  
Sufficient Information ◽  
Enterovirus Infection ◽  
Case Control Studies ◽  
Tissue Samples ◽  
Cochrane Database

ObjectiveThe association between enterovirus infection and type 1 diabetes (T1D) is controversial, and this meta-analysis aimed to explore the correlation.MethodsPubMed, Embase, Web of Science, and Cochrane Database were searched from inception to April 2020. Studies were included if they could provide sufficient information to calculate odds ratios and 95% confidence intervals. All analyses were performed using STATA 15.1.ResultsThirty-eight studies, encompassing 5921 subjects (2841 T1D patients and 3080 controls), were included. The pooled analysis showed that enterovirus infection was associated with T1D (P < 0.001). Enterovirus infection was correlated with T1D in the European (P < 0.001), African (P = 0.002), Asian (P = 0.001), Australian (P = 0.011), and Latin American (P = 0.002) populations, but no conclusion could be reached for North America. The association between enterovirus infection and T1D was detected in blood and tissue samples (both P < 0.001); no association was found in stool samples.ConclusionOur findings suggest that enterovirus infection is associated with T1D.

Frontline Science: Abnormalities in the gut mucosa of non‐obese diabetic mice precede the onset of type 1 diabetes

2019 ◽  
Vol 106 (3) ◽  
pp. 513-529 ◽  
Author(s):  
Mariana Camila Gonçalves Miranda ◽  
Rafael Pires Oliveira ◽  
Lícia Torres ◽  
Sarah Leão Fiorini Aguiar ◽  
Natalia Pinheiro‐Rosa ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Diabetic Mice ◽  
Gut Mucosa

scholarly journals Enterovirus Infection, CXC Chemokine Ligand 10 (CXCL10), and CXCR3 Circuit: A Mechanism of Accelerated  -Cell Failure in Fulminant Type 1 Diabetes

Diabetes ◽  
2009 ◽  
Vol 58 (10) ◽  
pp. 2285-2291 ◽  
Author(s):  
S. Tanaka ◽  
Y. Nishida ◽  
K. Aida ◽  
T. Maruyama ◽  
A. Shimada ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Enterovirus Infection ◽  
Fulminant Type 1 Diabetes ◽  
Cxc Chemokine ◽  
Chemokine Ligand ◽  
Fulminant Type

Enterovirus infection, β-cell apoptosis and type 1 diabetes

2013 ◽  
Vol 34 (3) ◽  
pp. 153 ◽  
Author(s):  
Sandhya Nair ◽  
Ammira Akil ◽  
Maria E Craig
Keyword(s):  
Type 1 Diabetes ◽  
Cell Apoptosis ◽  
Enterovirus Infection ◽  
Β Cell

scholarly journals Maternal Enterovirus Infection during Pregnancy as a Risk Factor in Offspring Diagnosed with Type 1 Diabetes between 15 and 30 Years of Age

2008 ◽  
Vol 2008 ◽  
pp. 1-6 ◽  
Author(s):  
Maria Elfving ◽  
Johan Svensson ◽  
Sami Oikarinen ◽  
Björn Jonsson ◽  
Per Olofsson ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Young Adulthood ◽  
Immunoglobulin M ◽  
Control Group ◽  
Enterovirus Infection ◽  
Group 14 ◽  
Serum Samples ◽  
Specific Immunoglobulin ◽  
Adolescence And Young Adulthood

Maternal enterovirus infections during pregnancy may increase the risk of offspring developing type 1 diabetes during childhood. The aim of this study was to investigate whether gestational enterovirus infections increase the offspring's risk of type 1 diabetes later in life. Serum samples from 30 mothers without diabetes whose offspring developed type 1 diabetes between 15 and 25 years of age were analyzed for enterovirus-specific immunoglobulin M (IgM) antibodies and enterovirus genome (RNA), and compared to a control group. Among the index mothers, 9/30 (30%) were enterovirus IgM-positive, and none was positive for enterovirus RNA. In the control group, 14/90 (16%) were enterovirus IgM-positive, and 4/90 (4%) were positive for enterovirus RNA (n.s.). Boys of enterovirus IgM-positive mothers had approximately 5 times greater risk of developing diabetes (OR 4.63; 95% CI 1.22–17.6), as compared to boys of IgM-negative mothers (P<.025). These results suggest that gestational enterovirus infections may be related to the risk of offspring developing type 1 diabetes in adolescence and young adulthood.

scholarly journals Maternal First-Trimester Enterovirus Infection and Future Risk of Type 1 Diabetes in the Exposed Fetus

Diabetes ◽  
2002 ◽  
Vol 51 (8) ◽  
pp. 2568-2571 ◽  
Author(s):  
H. R. Viskari ◽  
M. Roivainen ◽  
A. Reunanen ◽  
J. Pitkaniemi ◽  
K. Sadeharju ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
First Trimester ◽  
Enterovirus Infection ◽  
Future Risk

scholarly journals Enterovirus infection is associated with an increased risk of childhood type 1 diabetes in Taiwan: a nationwide population-based cohort study

Diabetologia ◽  
2014 ◽  
Vol 58 (1) ◽  
pp. 79-86 ◽  
Author(s):  
Hsiao-Chuan Lin ◽  
Chung-Hsing Wang ◽  
Fuu-Jen Tsai ◽  
Kao-Pin Hwang ◽  
Walter Chen ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Cohort Study ◽  
Population Based ◽  
Enterovirus Infection ◽  
Increased Risk ◽  
Childhood Type 1 Diabetes ◽  
Childhood Type
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