Insulin Restores Gestational Diabetes Mellitus-Reduced Adenosine Transport Involving Differential Expression of Insulin Receptor Isoforms in Human Umbilical Vein Endothelium

F. Westermeier; C. Salomon; M. Gonzalez; C. Puebla; E. Guzman-Gutierrez; F. Cifuentes; A. Leiva; P. Casanello; L. Sobrevia

doi:10.2337/db11-0155

Insulin Restores Gestational Diabetes Mellitus-Reduced Adenosine Transport Involving Differential Expression of Insulin Receptor Isoforms in Human Umbilical Vein Endothelium

Diabetes ◽

10.2337/db11-0155 ◽

2011 ◽

Vol 60 (6) ◽

pp. 1677-1687 ◽

Cited By ~ 72

Author(s):

F. Westermeier ◽

C. Salomon ◽

M. Gonzalez ◽

C. Puebla ◽

E. Guzman-Gutierrez ◽

...

Keyword(s):

Diabetes Mellitus ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

Insulin Receptor ◽

Differential Expression ◽

Umbilical Vein ◽

Human Umbilical Vein ◽

Receptor Isoforms ◽

Insulin Receptor Isoforms ◽

Adenosine Transport

Download Full-text

Insulin receptor isoforms: an integrated view focused on gestational diabetes mellitus

Diabetes/Metabolism Research and Reviews ◽

10.1002/dmrr.2729 ◽

2015 ◽

Vol 32 (4) ◽

pp. 350-365 ◽

Cited By ~ 23

Author(s):

F. Westermeier ◽

T. Sáez ◽

P. Arroyo ◽

F. Toledo ◽

J. Gutiérrez ◽

...

Keyword(s):

Diabetes Mellitus ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

Insulin Receptor ◽

Receptor Isoforms ◽

Insulin Receptor Isoforms

Download Full-text

Insulin requires normal expression and signaling of insulin receptor A to reverse gestational diabetes‐reduced adenosine transport in human umbilical vein endothelium

The FASEB Journal ◽

10.1096/fj.14-254219 ◽

2014 ◽

Vol 29 (1) ◽

pp. 37-49 ◽

Cited By ~ 34

Author(s):

Francisco Westermeier ◽

Carlos Salomón ◽

Marcelo Farías ◽

Pablo Arroyo ◽

Bárbara Fuenzalida ◽

...

Keyword(s):

Gestational Diabetes ◽

Insulin Receptor ◽

Umbilical Vein ◽

Human Umbilical Vein ◽

Normal Expression ◽

Adenosine Transport

Download Full-text

255: Alterations of calcium (Ca2+) signaling in human umbilical vein endothelial cells (HUVEC) suggesting a unique vascular adaptation in pre-existing diabetes mellitus (DM) versus gestational diabetes mellitus (GDM) pregnancies

American Journal of Obstetrics and Gynecology ◽

10.1016/j.ajog.2010.10.273 ◽

2011 ◽

Vol 204 (1) ◽

pp. S108-S109

Author(s):

Heather Bankowski ◽

Derek Boeldt ◽

Fu-Xian Yi ◽

Ian Bird ◽

Dinesh Shah

Keyword(s):

Diabetes Mellitus ◽

Endothelial Cells ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

Umbilical Vein ◽

Human Umbilical Vein ◽

Vascular Adaptation ◽

Umbilical Vein Endothelial Cells

Download Full-text

Human umbilical vein endothelium-derived exosomes play a role in foetoplacental endothelial dysfunction in gestational diabetes mellitus

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease ◽

10.1016/j.bbadis.2017.11.010 ◽

2018 ◽

Vol 1864 (2) ◽

pp. 499-508 ◽

Cited By ~ 24

Author(s):

Tamara Sáez ◽

Rocío Salsoso ◽

Andrea Leiva ◽

Fernando Toledo ◽

Paul de Vos ◽

...

Keyword(s):

Diabetes Mellitus ◽

Endothelial Dysfunction ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

Umbilical Vein ◽

Human Umbilical Vein

Download Full-text

High glucose induces dysfunction of human umbilical vein endothelial cells by upregulating miR-137 in gestational diabetes mellitus

Microvascular Research ◽

10.1016/j.mvr.2018.03.002 ◽

2018 ◽

Vol 118 ◽

pp. 90-100 ◽

Cited By ~ 8

Author(s):

Hai-Yan Peng ◽

Hua-Ping Li ◽

Ming-Qing Li

Keyword(s):

Diabetes Mellitus ◽

Endothelial Cells ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

High Glucose ◽

Umbilical Vein ◽

Human Umbilical Vein ◽

Umbilical Vein Endothelial Cells

Download Full-text

Hyperglycemia aggravates monocyte-endothelial adhesion in human umbilical vein endothelial cells from women with gestational diabetes mellitus by inducing Cx43 overexpression

Annals of Translational Medicine ◽

10.21037/atm-19-4738 ◽

2021 ◽

Vol 9 (3) ◽

pp. 234-234

Author(s):

Qian Zhang ◽

Shan Wu ◽

Guoliang Sun ◽

Rui Zhang ◽

Xianlong Li ◽

...

Keyword(s):

Diabetes Mellitus ◽

Endothelial Cells ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

Umbilical Vein ◽

Human Umbilical Vein ◽

Umbilical Vein Endothelial Cells

Download Full-text

Insulin therapy restores the equilibrative nucleoside transporter 1 expression in human umbilical vein endothelial cells from gestational diabetes mellitus

Placenta ◽

10.1016/j.placenta.2017.01.109 ◽

2017 ◽

Vol 51 ◽

pp. 130

Author(s):

L. Silva ◽

M. Subiabre ◽

R. Villalobos-Labra ◽

R. Salsoso ◽

A. López ◽

...

Keyword(s):

Diabetes Mellitus ◽

Endothelial Cells ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

Insulin Therapy ◽

Umbilical Vein ◽

Nucleoside Transporter ◽

Human Umbilical Vein ◽

Equilibrative Nucleoside Transporter ◽

Umbilical Vein Endothelial Cells

Download Full-text

Sodium/proton exchanger subtype 1 regulates intracellular pH in human umbilical vein endothelial cells from gestational diabetes mellitus

Placenta ◽

10.1016/j.placenta.2017.01.107 ◽

2017 ◽

Vol 51 ◽

pp. 129-130 ◽

Cited By ~ 1

Author(s):

J. Araos ◽

A. Saavedra ◽

C. Sanhueza ◽

A. Leiva ◽

M.A. Ramírez ◽

...

Keyword(s):

Diabetes Mellitus ◽

Endothelial Cells ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

Intracellular Ph ◽

Umbilical Vein ◽

Human Umbilical Vein ◽

Sodium Proton Exchanger ◽

Umbilical Vein Endothelial Cells

Download Full-text

Effect of gestational diabetes mellitus and pregnancy-induced hypertension on human umbilical vein smooth muscle KATP channels

Experimental and Molecular Pathology ◽

10.1016/j.yexmp.2019.104323 ◽

2019 ◽

Vol 111 ◽

pp. 104323 ◽

Cited By ~ 6

Author(s):

Vladimir Djokic ◽

Svetlana Jankovic-Raznatovic ◽

Radmila Novakovic ◽

Milan Kostic ◽

Jovana Rajkovic ◽

...

Keyword(s):

Diabetes Mellitus ◽

Smooth Muscle ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

Umbilical Vein ◽

Katp Channels ◽

Pregnancy Induced Hypertension ◽

Human Umbilical Vein ◽

Induced Hypertension

Download Full-text

Influence of gestational diabetes mellitus on human umbilical vein endothelial cell miRNA

Clinical Science ◽

10.1042/cs20160305 ◽

2016 ◽

Vol 130 (21) ◽

pp. 1955-1967 ◽

Cited By ~ 28

Author(s):

Jeanie B. Tryggestad ◽

Anu Vishwanath ◽

Shaoning Jiang ◽

Ashwini Mallappa ◽

April M. Teague ◽

...

Keyword(s):

Diabetes Mellitus ◽

Metabolic Disease ◽

Endothelial Cell ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

Mirna Expression ◽

Umbilical Vein ◽

In Utero ◽

In Utero Exposure ◽

Human Umbilical Vein

In utero exposure to diabetes results in changes in miRNA expression. These changes affect target proteins known to function in energy homoeostasis and may predispose the children to future metabolic disease.

Download Full-text