High Glucose Suppresses Epidermal Growth Factor Receptor/Phosphatidylinositol 3-Kinase/Akt Signaling Pathway and Attenuates Corneal Epithelial Wound Healing

K.-P. Xu; Y. Li; A. V. Ljubimov; F.-S. X. Yu

doi:10.2337/db08-0997

High Glucose Suppresses Epidermal Growth Factor Receptor/Phosphatidylinositol 3-Kinase/Akt Signaling Pathway and Attenuates Corneal Epithelial Wound Healing

Diabetes ◽

10.2337/db08-0997 ◽

2009 ◽

Vol 58 (5) ◽

pp. 1077-1085 ◽

Cited By ~ 80

Author(s):

K.-P. Xu ◽

Y. Li ◽

A. V. Ljubimov ◽

F.-S. X. Yu

Keyword(s):

Wound Healing ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Growth Factor Receptor ◽

Akt Signaling ◽

Akt Signaling Pathway ◽

Phosphatidylinositol 3 Kinase ◽

Corneal Epithelial ◽

Epithelial Wound Healing ◽

Epidermal Growth

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Survivin Expression Is Regulated by Coexpression of Human Epidermal Growth Factor Receptor 2 and Epidermal Growth Factor Receptor via Phosphatidylinositol 3-Kinase/AKT Signaling Pathway in Breast Cancer Cells

Cancer Research ◽

10.1158/0008-5472.can-05-0491 ◽

2005 ◽

Vol 65 (23) ◽

pp. 11018-11025 ◽

Cited By ~ 121

Author(s):

Hiroko Asanuma ◽

Toshihiko Torigoe ◽

Kenjiro Kamiguchi ◽

Yoshihiko Hirohashi ◽

Tousei Ohmura ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Breast Cancer Cells ◽

Growth Factor Receptor ◽

Survivin Expression ◽

Akt Signaling ◽

Akt Signaling Pathway ◽

Phosphatidylinositol 3 Kinase ◽

Epidermal Growth

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Lysophosphatidic Acid Promoting Corneal Epithelial Wound Healing by Transactivation of Epidermal Growth Factor Receptor

Investigative Opthalmology & Visual Science ◽

10.1167/iovs.06-0203 ◽

2007 ◽

Vol 48 (2) ◽

pp. 636 ◽

Cited By ~ 42

Author(s):

Ke-Ping Xu ◽

Jia Yin ◽

Fu-Shin X. Yu

Keyword(s):

Wound Healing ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Lysophosphatidic Acid ◽

Growth Factor Receptor ◽

Corneal Epithelial ◽

Epithelial Wound Healing ◽

Epidermal Growth

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Ionizing Radiation Enhances Matrix Metalloproteinase-2 Secretion and Invasion of Glioma Cells through Src/Epidermal Growth Factor Receptor-Mediated p38/Akt and Phosphatidylinositol 3-Kinase/Akt Signaling Pathways

Yearbook of Pathology and Laboratory Medicine ◽

10.1016/s1077-9108(08)70678-9 ◽

2008 ◽

Vol 2008 ◽

pp. 231-233

Author(s):

C. Horbinski

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Matrix Metalloproteinase ◽

Growth Factor Receptor ◽

Glioma Cells ◽

Akt Signaling ◽

Matrix Metalloproteinase 2 ◽

Phosphatidylinositol 3 Kinase ◽

Epidermal Growth

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Cross Talk between c-Met and Epidermal Growth Factor Receptor during Retinal Pigment Epithelial Wound Healing

Investigative Opthalmology & Visual Science ◽

10.1167/iovs.06-0560 ◽

2007 ◽

Vol 48 (5) ◽

pp. 2242 ◽

Cited By ~ 51

Author(s):

Ke-Ping Xu ◽

Fu-Shin X. Yu

Keyword(s):

Wound Healing ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Retinal Pigment Epithelial ◽

Retinal Pigment ◽

Growth Factor Receptor ◽

Pigment Epithelial ◽

Epithelial Wound Healing ◽

Epidermal Growth

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microRNA-133a regulates the cell cycle and proliferation of breast cancer cells by targeting epidermal growth factor receptor through the EGFR/Akt signaling pathway

FEBS Journal ◽

10.1111/febs.12398 ◽

2013 ◽

Vol 280 (16) ◽

pp. 3962-3974 ◽

Cited By ~ 58

Author(s):

Wenjing Cui ◽

Shuai Zhang ◽

Changliang Shan ◽

Li Zhou ◽

Zhemin Zhou

Keyword(s):

Breast Cancer ◽

Cell Cycle ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Breast Cancer Cells ◽

Growth Factor Receptor ◽

Akt Signaling ◽

Akt Signaling Pathway ◽

Epidermal Growth

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Protease-activated receptor-2 activation enhances epithelial wound healing via epidermal growth factor receptor

Tissue Barriers ◽

10.1080/21688370.2021.1968763 ◽

2021 ◽

Author(s):

Mahesha Bandara ◽

Wallace K. MacNaughton

Keyword(s):

Wound Healing ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Epithelial Wound Healing ◽

Epidermal Growth ◽

Protease Activated Receptor 2

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Blockage of Epidermal Growth Factor Receptor-Phosphatidylinositol 3-Kinase-AKT Signaling Increases Radiosensitivity of K-RAS Mutated Human Tumor Cells In vitro by Affecting DNA Repair

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-05-2454 ◽

2006 ◽

Vol 12 (13) ◽

pp. 4119-4126 ◽

Cited By ~ 153

Author(s):

Mahmoud Toulany ◽

Ulla Kasten-Pisula ◽

Ingo Brammer ◽

Shaomeng Wang ◽

Jianyong Chen ◽

...

Keyword(s):

Dna Repair ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Growth Factor Receptor ◽

Human Tumor ◽

Akt Signaling ◽

Phosphatidylinositol 3 Kinase ◽

Human Tumor Cells ◽

Epidermal Growth

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Kaempferol potentiates the sensitivity of pancreatic cancer cells to erlotinib via inhibition of the PI3K/AKT signaling pathway and epidermal growth factor receptor

Inflammopharmacology ◽

10.1007/s10787-021-00848-1 ◽

2021 ◽

Author(s):

Zhengguang Zhang ◽

Yuanyuan Guo ◽

Meijuan Chen ◽

Feiyan Chen ◽

Bing Liu ◽

...

Keyword(s):

Pancreatic Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Cancer Cells ◽

Growth Factor Receptor ◽

Akt Signaling ◽

Akt Signaling Pathway ◽

Pancreatic Cancer Cells ◽

Epidermal Growth

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Green Tea Attenuates Angiotensin II-Induced Cardiac Hypertrophy in Rats by Modulating Reactive Oxygen Species Production and the Src/Epidermal Growth Factor Receptor/Akt Signaling Pathway

Journal of Nutrition ◽

10.1093/jn/138.9.1596 ◽

2008 ◽

Vol 138 (9) ◽

pp. 1596-1601 ◽

Cited By ~ 28

Author(s):

Italia Papparella ◽

Giulio Ceolotto ◽

Domenico Montemurro ◽

Michele Antonello ◽

Spiridione Garbisa ◽

...

Keyword(s):

Reactive Oxygen Species ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Reactive Oxygen Species Production ◽

Growth Factor Receptor ◽

Akt Signaling ◽

Oxygen Species ◽

Akt Signaling Pathway ◽

Epidermal Growth ◽

Species Production

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Ionizing Radiation Enhances Matrix Metalloproteinase-2 Secretion and Invasion of Glioma Cells through Src/Epidermal Growth Factor Receptor–Mediated p38/Akt and Phosphatidylinositol 3-Kinase/Akt Signaling Pathways

Cancer Research ◽

10.1158/0008-5472.can-05-4340 ◽

2006 ◽

Vol 66 (17) ◽

pp. 8511-8519 ◽

Cited By ~ 188

Author(s):

Chang-Min Park ◽

Myung-Jin Park ◽

Hee-Jin Kwak ◽

Hyung-Chahn Lee ◽

Mi-Suk Kim ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Matrix Metalloproteinase ◽

Growth Factor Receptor ◽

Glioma Cells ◽

Akt Signaling ◽

Matrix Metalloproteinase 2 ◽

Phosphatidylinositol 3 Kinase ◽

Epidermal Growth

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