scholarly journals Impact of Common Type 2 Diabetes Risk Polymorphisms in the DESIR Prospective Study

Diabetes ◽  
2007 ◽  
Vol 57 (1) ◽  
pp. 244-254 ◽  
Author(s):  
M. Vaxillaire ◽  
J. Veslot ◽  
C. Dina ◽  
C. Proenca ◽  
S. Cauchi ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Prospective Study ◽  
Common Type ◽  
Diabetes Risk

scholarly journals Combining Information from Common Type 2 Diabetes Risk Polymorphisms Improves Disease Prediction

PLoS Medicine ◽  
2006 ◽  
Vol 3 (10) ◽  
pp. e374 ◽  
Author(s):  
Michael N Weedon ◽  
Mark I McCarthy ◽  
Graham Hitman ◽  
Mark Walker ◽  
Christopher J Groves ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Common Type ◽  
Diabetes Risk ◽  
Disease Prediction ◽  
Combining Information

scholarly journals Evaluation of Common Type 2 Diabetes Risk Variants in a South Asian Population of Sri Lankan Descent

PLoS ONE ◽  
2014 ◽  
Vol 9 (6) ◽  
pp. e98608 ◽  
Author(s):  
Neelam Hassanali ◽  
N. Maneka G. De Silva ◽  
Neil Robertson ◽  
N. William Rayner ◽  
Amy Barrett ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
South Asian ◽  
Asian Population ◽  
Common Type ◽  
Diabetes Risk ◽  
Sri Lankan ◽  
South Asian Population ◽  
Risk Variants

scholarly journals Impact of common type 2 diabetes risk gene variants on future type 2 diabetes in the non-diabetic population in Korea

2012 ◽  
Vol 57 (4) ◽  
pp. 265-268 ◽  
Author(s):  
Se Eun Park ◽  
Won Young Lee ◽  
Ki Won Oh ◽  
Ki Hyun Baek ◽  
Kun Ho Yoon ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Common Type ◽  
Diabetes Risk ◽  
Gene Variants ◽  
Risk Gene ◽  
Diabetic Population

scholarly journals A Common Type 2 Diabetes Risk Variant Potentiates Activity of an Evolutionarily Conserved Islet Stretch Enhancer and Increases C2CD4A and C2CD4B Expression

2018 ◽  
Vol 102 (4) ◽  
pp. 620-635 ◽  
Author(s):  
Ina Kycia ◽  
Brooke N. Wolford ◽  
Jeroen R. Huyghe ◽  
Christian Fuchsberger ◽  
Swarooparani Vadlamudi ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Common Type ◽  
Diabetes Risk ◽  
Risk Variant ◽  
Evolutionarily Conserved

scholarly journals A genetic risk score that includes common type 2 diabetes risk variants is associated with gestational diabetes

2017 ◽  
Vol 87 (2) ◽  
pp. 149-155 ◽  
Author(s):  
V. K. Kawai ◽  
R. T. Levinson ◽  
A. Adefurin ◽  
D. Kurnik ◽  
S. P. Collier ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Gestational Diabetes ◽  
Risk Score ◽  
Genetic Risk ◽  
Genetic Risk Score ◽  
Common Type ◽  
Diabetes Risk ◽  
Risk Variants

scholarly journals Cholesterol and egg intakes and the risk of type 2 diabetes: The Japan Public Health Center-based Prospective Study

2014 ◽  
Vol 112 (10) ◽  
pp. 1636-1643 ◽  
Author(s):  
Kayo Kurotani ◽  
Akiko Nanri ◽  
Atsushi Goto ◽  
Tetsuya Mizoue ◽  
Mitsuhiko Noda ◽  
...  
Keyword(s):  
Public Health ◽  
Type 2 Diabetes ◽  
Prospective Study ◽  
Health Center ◽  
Postmenopausal Women ◽  
Dietary Cholesterol ◽  
Diabetes Risk ◽  
Public Health Center ◽  
Cholesterol Intake

Limited and inconsistent associations between cholesterol and egg consumption and type 2 diabetes risk have been observed in Western countries. In the present study, the association of dietary cholesterol and egg intakes with type 2 diabetes risk was examined prospectively. The study subjects comprised 27 248 men and 36 218 women aged 45–75 years who participated in the second survey of the Japan Public Health Center-based Prospective Study and had no histories of type 2 diabetes or other serious diseases. Dietary cholesterol and egg intakes were estimated using a validated 147-item FFQ. The OR of self-reported, physician-diagnosed type 2 diabetes over 5 years were estimated using multiple logistic regression. A total of 1165 newly diagnosed cases of type 2 diabetes were self-reported. Although dietary cholesterol intake was not associated with type 2 diabetes risk in men, it was found to be associated with a 23 % lower odds of type 2 diabetes risk in women in the highest quartile of intake, albeit not statistically significant, compared with those in the lowest quartile (Ptrend= 0·08). Such risk reduction was somewhat greater among postmenopausal women; the multivariable-adjusted OR for the highest quartile of cholesterol intake compared with the lowest quartile was 0·68 (95 % CI 0·49, 0·94; Ptrend= 0·04). No association between egg intake and type 2 diabetes risk was found in either men or women. In conclusion, higher intake of cholesterol or eggs may not be associated with an increased risk of type 2 diabetes in Japanese populations. The observed association between decreased type 2 diabetes risk and higher dietary cholesterol intake in postmenopausal women warrants further investigation.

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