scholarly journals Clinico-pathological Studies of Periodontal Disease with Special Reference to Statistical Analysis between Histological Findings and Clinical Signs

1980 ◽  
Vol 22 (4) ◽  
pp. 555-574
Author(s):  
Michinobu SUGAWARA
Keyword(s):  
Statistical Analysis ◽  
Periodontal Disease ◽  
Special Reference ◽  
Clinical Signs ◽  
Histological Findings

scholarly journals Ischemic myelopathy caused by fibrocartilaginous embolism in a horse

2018 ◽  
Vol 48 (2) ◽  
Author(s):  
Welden Panziera ◽  
Ronaldo Michel Bianchi ◽  
Paula Reis Pereira ◽  
Mariana Martins Flores ◽  
Monique Togni ◽  
...  
Keyword(s):  
Cross Sections ◽  
Clinical Course ◽  
Clinical Signs ◽  
Histological Findings ◽  
Hind Limbs ◽  
Fibrocartilaginous Embolism ◽  
Mixed Breed ◽  
Liquefactive Necrosis ◽  
Gross Lesions ◽  
Multiple Blood

ABSTRACT: This report described clinical, epidemiological, and pathological aspects of ischemic myelopathy caused by fibrocartilaginous embolism (FCE) in a 10-year-old, mixed breed gelding. Clinically, the horse presented acute hind limbs paralysis, with a clinical course of approximately 24 hours. At necropsy, no gross lesions were observed. Cross-sections of the spinal cord revealed focally extensive areas of malacia from the T10 to L4 segments. Focally extensive areas of liquefactive necrosis involving the gray matter and adjacent white matter were observed on histologic sections. The lumen of multiple blood vessels in the periphery of the necrotic areas was occluded by fibrocartilaginous emboli that strongly stained with alcian blue. Clinical signs, gross necropsy, and histological findings observed in this case were identical to those described in the literature for ischemic myelopathy caused by FCE in the horse and other species.

Association of Periodontal Disease and Histologic Lesions in Multiple Organs from 45 Dogs

1996 ◽  
Vol 13 (2) ◽  
pp. 57-60 ◽  
Author(s):  
Linda J. DeBowes ◽  
Derek Mosier ◽  
Ellen Logan ◽  
Colin E. Harvey ◽  
Stephen Lowry ◽  
...  
Keyword(s):  
Lymph Node ◽  
Statistical Analysis ◽  
Periodontal Disease ◽  
Papillary Muscle ◽  
Mitral Valves ◽  
Tracheobronchial Lymph Node ◽  
Multiple Organs ◽  
Submandibular Lymph Node ◽  
Mixed Breed ◽  
Histopathologic Changes

Forty-five mixed breed dogs were evaluated for the presence and extent of periodontal disease. Histopathology was performed on samples of lung, myocardium, liver, kidney, tonsil, spleen, submandibular lymph node and tracheobronchial lymph node. Mitral valves were evaluated grossly. Statistical analysis was used to determine if there was a relationship between the extent of periodontal disease and histopathologic changes in the tissues examined. In the forty-five dogs studied, an association was found between periodontal disease and histopathologic changes in kidney, myocardium (papillary muscle), and liver.

scholarly journals Histopathological findings in horses with and without clinical signs of rhabdomyolysis with special reference to polysaccharide storage myopathy

2008 ◽  
Vol 53 (No. 12) ◽  
pp. 660-667 ◽  
Author(s):  
E. Ludvikova ◽  
I.D. Wijnberg ◽  
P. Fictum ◽  
Z. Lukas ◽  
J.H. van der Kolk ◽  
...  
Keyword(s):  
Special Reference ◽  
Clinical Signs ◽  
Size Variation ◽  
Clinical History ◽  
Histopathological Findings ◽  
Exertional Rhabdomyolysis ◽  
Fibre Size ◽  
Significant Difference ◽  
Polysaccharide Storage Myopathy ◽  
History Of

Objective of the study was to assess histopathological changes in horses with a clinical history of exertional rhabdomyolysis (ER) with special reference to polysaccharide storage myopathy and to compare histopathological findings in horses with and without a clinical history of ER. In total 39 muscle samples were collected, from horses with a history of repeated episodes of exertional rhabdomyolysis (test group, 10 horses) and from horses without clinical signs of muscular disorders in their history (control group, 29 horses). Frozen muscle samples were stained with haematoxylin and eosin and periodic acid-Schiff with and without amylase digestion. Histopathologic changes (amylase resistant polysaccharide, subsarcolemmal glycogen, intracytoplasmic masses, subsarcolemmal vacuoles, fibre size variation and internal nuclei) were evaluated. There was a statistically significant difference between groups in the presence of subsarcolemmal amylase sensitive glycogen deposits (P ≤ 0.0001), the risk ratio was 5.22. Statistically significant differences between groups were not found regarding the presence of intracytoplasmic masses, subsarcolemmal vacuoles, amylase resistant polysaccharide, fibre size variation and internal nuclei. Presence of amylase resistant polysaccharide within muscle fibres of apparently healthy horses could be a manifestation of different phenotype expression of PSSM but also the insufficient specificity of this diagnostic criterion.

scholarly journals Electrophoretic and Immunological Studies on Sera from Calves from Birth to Weaning II. Electrophoretic and Serological Studies with Special Reference to the Normal and Induced Agglutinins to Trichomonas Foetus

1955 ◽  
Vol 53 (3) ◽  
pp. 261-275 ◽  
Author(s):  
A. E. Pierce
Keyword(s):  
Statistical Analysis ◽  
Special Reference ◽  
Early Life ◽  
Normal Adult ◽  
Neonatal Calf ◽  
Serological Studies

Summary1. The lacto-globulin in bovine colostral whey, and the γ globulin in the serum contain the normal and induced agglutinins to the protozoon Trichomonas foetus.2. A decline in γ globulin in sera from cattle approaching calving may be associated with the concentration of the lacto-globulin in the udder.3. The elimination of the passive normal and induced agglutinins acquired by the neonatal calf was logarithmic. The autogenous production of γ globulin by the calf occurred soon after birth, resulting in an apparent decline in the rate of elimination of the lacto-globulins.4. The autogenous production of γ globulin was not necessarily accompanied by that of detectable normal agglutinin.5. Calves injected with T. foetus antigen within the first 3 weeks of life, and in which there was evidence of autogenous γ globulin, developed normal autogenous but not induced agglutinins.6. Calves which received colostrum containing maternal induced and normal agglutinins, calves partially deprived of colostrum, and calves immunized in early life, produced the normal autogenous agglutinin between the 30th and 60th days, reaching the normal adult titre of 1/48–1/96.7. The properties of the normal agglutinins were investigated. They possess some characteristics significantly different from those of the induced agglutinins. These suggested that the normal agglutinins were γ globulin molecules with an ‘accidental’ genetic configuration complementary to T. foetus.The author wishes to thank Dr M. Robertson, F.R.S., and Sir Alan Drury, F.R.S. for their interest and encouragement during the course of this work, and Dr R. C. Campbell for the statistical analysis.

scholarly journals Milyen hatása van a COVID–19-járványnak a gyermekkori akut appendicitisekre?

2021 ◽  
Vol 162 (16) ◽  
pp. 608-610
Author(s):  
Balázs Fadgyas ◽  
Gábor István Garai ◽  
Zoltán Ringwald
Keyword(s):  
Statistical Analysis ◽  
Acute Appendicitis ◽  
Antibiotic Treatment ◽  
Laparoscopic Appendectomy ◽  
Perforated Appendicitis ◽  
Complicated Appendicitis ◽  
Histological Findings ◽  
Exact Test ◽  
Fisher's Exact Test ◽  
Fisher’S Exact Test

Összefoglaló. Bevezetés: A COVID–19-pandémia miatt a gyermekkori appendicitisek kezelésében számos változás történt (laparoszkópia helyett nyílt műtét, antibiotikumkezelés). Világszerte emelkedett a szövődményes appendicitisek aránya. Célkitűzés: Munkánk során a COVID–19-járványnak a gyermekkori akut appendicitisekre kifejtett hatását szerettük volna vizsgálni: lett-e több perforált eset? Módszerek: A 2012 és 2020 között akut vakbélgyulladás miatt operált gyermekeket vizsgáltuk, külön, havi bontásban a 2020-as eseteket. A szövettani diagnózis alapján perforált és nem perforált appendicitis csoportokat alkottunk. A 2020-ban operált betegek COVID–19-statusát is rögzítettük. Statisztikai analízisre a khi2-próbát (’chi2 test for trend’) és a Fisher-féle egzakt tesztet alkalmaztuk. Eredmények: A vizsgált időszakban 1343 appendectomia történt, többségében nem perforált akut appendicitis miatt (1166/1343). 2015-től kezdődően a perforált esetek aránya szignifikáns emelkedést mutat (p = 0,0002). Az igazoltan COVID–19-pozitív betegek között magasabb volt a perforáltak aránya (5/8), mint az igazoltan negatív betegek között (15/92) (p = 0,0075). Megbeszélés: A nemzetközi trendeknek megfelelően 2020-ban osztályunkon is magasabb volt a perforált appendicitisek aránya, mint a korábbi években. Ez az emelkedés 2015-től tart, a pandémiával nem mutat szoros összefüggést. A perforált appendicitisek COVID–19-pozitív betegek között észlelt magas arányának okát nem ismerjük. Következtetés: További vizsgálat indokolt annak feltárására, hogy mi okozza a perforált appendicitisek COVID–19-pozitív betegek között észlelt magas, illetve 2015 óta emelkedő rátáját. Orv Hetil. 2021; 162(16): 608–610. Summary. Introduction: As a result of the COVID-19 pandemic, the management of paediatric appendicitis has changed (open instead of laparoscopic appendectomy, antibiotic treatment). The number of complicated appendicitis cases increased worldwide. Objective: Our aim was to study the effect of the COVID-19 pandemic on paediatric acute appendicitis: has there been more perforated cases? Methods: Children operated because of acute appendicitis between 2012 and 2020 were studied. Cases from the year 2020 were analysed monthly. Patients were divided into perforated and non-perforated appendicitis groups according to their histological findings. COVID-19 status of patients in 2020 was studied. Chi2 test for trend and Fisher’s exact test were used for statistical analysis. Results: In the study period, 1343 appendectomies were performed. The majority of our cases were non-perforated (1166/1343). The rate of perforated appendicitis cases has been increasing from 2015 (p = 0.0002). The number of perforated cases was higher in COVID-19 positive patients (5/8) then in negative ones (15/92) (p = 0.0075). Discussion: In line with the international trend, more perforated appendicitis cases were treated in our departement in 2020. However, this increase started in 2015, and there is no correlation with the COVID-19 pandemic. The cause of the increased number of perforated cases in COVID-19 positive appendicitis patients is unknown. Conclusion: The causes of the high proportion of perforated cases in COVID-19 positive patients and the rising rate of perforated appendicitis cases since 2015 need further studies. Orv Hetil. 2021; 162(16): 608–610.

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